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Targeted therapy treats mixed histiocytosis following multiple skull relapses

Mixed histiocytosis (Langerhans cell histiocytosis [LCH] / Erdheim-Chester disease [ECD]) developing after treatment for initial skull LCH is not well recognized.

13 Apr 2026

Competition between brain circuits is key to intelligent behavior

The brain does not only cooperate; it also competes. So determines an international study by the University of Oxford, the University of Cambridge, Pompeu Fabra University and the Montreal Neurological Institute in Canada, published in Nature Neuroscience.

13 Apr 2026

Minimally-invasive stenting effectively treats painful post-thrombotic syndrome

A major multi-site clinical trial co-led by researchers at Washington University School of Medicine in St. Louis has shown that post-thrombotic syndrome - a common and often painful complication suffered by many people who have experienced blockages of major veins due to blood clots - can be effectively treated with a minimally invasive procedure.

13 Apr 2026

Clinical trial tests laser therapy for vaginal dryness in breast cancer survivors

The Alliance for Clinical Trials in Oncology is now enrolling patients into a clinical trial aimed at helping women recover from the vaginal side effects of breast cancer treatment.

13 Apr 2026

Targeting senescent fat cells provides new hope for ovarian cancer

Ovarian cancer is the most lethal malignancy of the female reproductive system. Due to its insidious early symptoms and the absence of specific screening modalities, approximately 70% of patients are diagnosed at an advanced stage.

13 Apr 2026

Metformin protects neurons after brain injury by restoring mitochondrial health

TBI remains a major cause of death and long-term neurological disability worldwide, yet effective treatments for secondary injury are still lacking.

13 Apr 2026

NTU Singapore and partners develop new inhaled treatment for severe lung infections

Nanyang Technological University, Singapore (NTU Singapore) is working with China's Southern University of Science and Technology (SUSTech) and Swedish biotechnology company Lipigon Pharmaceuticals AB to develop a new inhaled treatment aimed at helping patients recover faster from severe lung infections.

13 Apr 2026

Bayer receives MHRA approval for Kerendia® (finerenone) in adults with heart failure with LVEF ≥ 40 %

The Medicines and Healthcare products Regulatory Agency (MHRA) has granted approval for Kerendia® (finerenone), a non-steroidal, selective mineralocorticoid receptor antagonist (nsMRA), for the treatment of symptomatic chronic heart failure (HF) with left ventricular ejection fraction (LVEF) ≥ 40 %, in adults in the UK.

From Bayer PLC 13 Apr 2026

Young cancer survivors face double the risk of later cancers

Survivors of cancer in their teen and young adult years are at double the risk of most types of later cancers, according to research from Alberta published in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.251381.

13 Apr 2026

Natural peptide PEPITEM shows promise in reducing arthritic joint swelling

Scientists investigating the naturally occurring immunopeptide PEPITEM have shown reductions in arthritic joint swelling to a degree comparable to the current standard of care, and reduce the inflammatory changes that cause joint damage.

13 Apr 2026

Stanford researchers create noninvasive way to deliver light deep inside the body

Light has an increasing number of applications in biology and medicine – it can be used to stimulate cell growth, manipulate neural signals, and treat some cancers – but it doesn't easily pass through tissue.

13 Apr 2026

Dietitians report widely different strategies for FODMAP food reintroduction in IBS

A national survey of 145 registered dietitians found wide variation in how the low FODMAP diet’s reintroduction phase is delivered, especially in dosing, timing, sequencing, and follow-up. The findings suggest that clearer, evidence-based protocols could improve consistency while still allowing individualized care.

12 Apr 2026

Letrozole monotherapy falls short in ovarian cancer clinical trial

Late breaking results from the phase III NRG GY019 trial indicate that letrozole monotherapy (L) did not demonstrate non inferiority to paclitaxel/carboplatin followed by letrozole (PC/L) for progression free survival (PFS) in patients with newly diagnosed stage II-IV low grade serous carcinoma of the ovary or peritoneum.

11 Apr 2026

Mezagitamab shows promise in treating immune thrombocytopenia patients

Results from a phase 2 clinical trial designed and overseen by researchers at Mass General Brigham Cancer Institute show that the investigational medication mezagitamab can effectively boost platelet counts in patients with immune thrombocytopenia (ITP), an autoimmune disease characterized by elevated platelet destruction and reduced platelet production that increases bleeding risk and compromises quality of life.

11 Apr 2026

Study reveals why immunotherapy fails in pancreatic cancer

Researchers at Oregon Health & Science University have uncovered a key reason why immunotherapy has largely failed in pancreatic cancer - and identified a promising strategy to overcome that resistance.

11 Apr 2026

Damon Runyon supports young scientists driving cancer research innovation

The Damon Runyon Cancer Research Foundation has named 13 new Damon Runyon Fellows, exceptional postdoctoral scientists conducting basic and translational cancer research in the laboratories of leading senior investigators.

11 Apr 2026

Pseudogene lncRNAs regulate cancer stem cell behavior and signaling

Cancer stem cells (CSCs), a critical subpopulation within tumors, drive cancer initiation, progression, metastasis, relapse, and resistance to therapy due to their innate capacity for self-renewal and differentiation.

11 Apr 2026

PRRDetect algorithm could one day revolutionize the treatment of cancer

Researchers have created a "metal detector" algorithm called PRRDetect to hunt down vulnerable tumors, in a development that could one day revolutionize the treatment of cancer.

11 Apr 2026

EV-RNAs show promise for IBD diagnosis and treatment

A research team led by Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine, has published a comprehensive review in ExRNA that sorts out the diverse roles of extracellular vesicle-associated RNAs (EV-RNAs) in the development and progression of inflammatory bowel disease (IBD).

10 Apr 2026

Non-clinical safety assessment crucial for CRISPR-based gene therapies

The rapid evolution of CRISPR/Cas genome editing has redefined the possibilities of cellular and gene therapy, enabling precise correction, disruption, and regulation of disease-associated genes.

10 Apr 2026