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Heart pump technology - comparative study

Chicago's first participant in the RELIANT (Randomized Evaluation of the Novacor(r) LVAS In A Non-Transplant Population) research study recently went home from Northwestern Memorial Hospital.

5 Dec 2005

Cerebrospinal fluid analysis combined with brain scan predicts Alzheimer's

A combination of brain scanning with a new imaging agent and cerebrospinal fluid (CSF) analysis has left neuroscientists encouraged that they may finally be moving toward techniques for diagnosing Alzheimer's disease before its clinical symptoms become apparent.

5 Dec 2005

Ack1 molecule stimulates the aggressive growth of prostate cancer

The molecule, Ack1, a member of the growth-promoting tyrosine kinase gene family, stimulates tumor formation in part by signaling prostate cells to rid themselves of a tumor-suppressor protein. Normally, this suppressor protein would inhibit rapid cell growth by signaling the cell to destroy itself.

5 Dec 2005

Alagebrium may prevent arterial aging in patients with systolic hypertension

A compound called alagebrium, which is very similar to another used in anti-wrinkle creams, may be useful in reducing the deleterious effects of arterial aging in the majority of elderly Americans with systolic hypertension, a new study from researchers at Johns Hopkins shows.

5 Dec 2005

Aldosterone shows promise as stroke treatment

A bi-polar hormone that can contribute to strokes and minimize their damage is emerging as a therapeutic target in the battle against these brain attacks, researchers say.

5 Dec 2005

The earlier cochlear implants considered, the better

New research at Johns Hopkins has clearly demonstrated the ability of cochlear implants in very young animals to forge normal nerve fibers that transmit sound and to restore hearing by reversing or preventing damage to the brain's auditory system.

5 Dec 2005

LEDGF protein controls the location of HIV integration in human cells

A human DNA-associated protein called LEDGF is the first such molecule found to control the location of HIV integration in human cells, according to researchers at the University of Pennsylvania School of Medicine.

5 Dec 2005

Telemammography works

Digital mammography images can be accurately transmitted over broadband Internet, according to a study presented at the annual meeting of the Radiological Society of North America (RSNA).

5 Dec 2005

Genetics play a part in the inability to stop caffeine use

A study led by Johns Hopkins investigators has shown that women with a serious caffeine habit and a family history of alcohol abuse are more likely to ignore advice to stop using caffeine during pregnancy.

5 Dec 2005

Ultrafiltration therapy safe and effective

A device that performs ultrafiltration of blood, without requiring specialized nursing care or invasive central intravenous access, can reduce fluid overload in patients with congestive heart failure, according to a new study in the Dec. 6, 2005, issue of the Journal of the American College of Cardiology.

5 Dec 2005

Phenoxodiol - docetaxel combination for women with recurrent ovarian cancer

A clinical study of ovarian cancer initiated by investigators at Yale School of Medicine will combine the anti-cancer drug phenoxodiol with docetaxel for women with recurrent ovarian cancer.

5 Dec 2005

Researchers link microRNA - miR 196 - to limb development

A tiny strand of molecules plays a role in how our arms and legs develop and grow - a finding that sheds light on perplexing bits of material once dismissed as genetic "junk," say scientists at the University of Florida and Harvard University.

5 Dec 2005

Researchers move in on novel therapeutics to inhibit melanoma

Northwestern University researchers have developed a novel, three-dimensional model that allows scientists to observe how interacting with the microenvironment of metastatic melanoma cells induces normal skin cells to become similar to aggressive cancer cells that migrate and spread throughout the body.

5 Dec 2005

Sleep-disorders related to breathing suggest increase risk of stroke

Individuals who experience moderate to severe sleep-disordered breathing are four times more likely to have a stroke during the next four years than those who do not suffer from the problem.

5 Dec 2005

CFH Y402H confers similar risk of soft drusen and both forms of advanced AMD

Gene is associated with increased risk of precursor of macular degeneration A variant in a gene called Complement Factor H (CFH) appears to contribute to the increased risk of advanced age-related macular degeneration (AMD) largely or entirely through its impact on the development of a precursor of advanced AMD called soft drusen (small yellowish, extracellular deposits of lipid, protein and cellular debris in the back of the eye), according to a multinational team of researchers.

2 Dec 2005

Discovery of genetic mechanism that causes new arteries to grow in response to blocked arteries

Researchers at the San Francisco VA Medical Center have uncovered part of the genetic mechanism that causes new arteries to grow in response to blocked arteries.

2 Dec 2005

Fast-tracked screening for Chlamydia in UK

Young women asking for the morning-after pill at pharmacies will be offered fast-tracked screening for Chlamydia, the UK's most common sexually transmitted infection, in a University of Manchester study.

From The University of Manchester 2 Dec 2005

Making angioplasty safer

When life-threatening problems occur during angioplasty procedures, doctors may perform emergency coronary artery bypass graft surgery, but data from the Mayo Clinic indicates that need to send patients to emergency surgery has dropped sharply, according to a new study in the Dec. 6, 2005, issue of the Journal of the American College of Cardiology.

2 Dec 2005

Significant relationships between household endotoxin and diagnosed asthma

Exposure to household endotoxin levels poses a significant risk for asthma, according to the first nationwide sampling of house dust.

2 Dec 2005

Depressed heart patients skip medications

Recent studies conducted at the San Francisco VA Medical Center suggest two possible mechanisms for the widely recognized link between depression and adverse outcomes in patients with coronary heart disease: lack of adherence to medication regimens and increased levels of norepinephrine, a stress hormone.

2 Dec 2005