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Gene therapy success for the treatment of congenital muscular dystrophy (CMD) in mice

Researchers from the University of Pittsburgh report the first study to achieve success with gene therapy for the treatment of congenital muscular dystrophy (CMD) in mice, demonstrating that the formidable scientific challenges that have cast doubt on gene therapy ever being feasible for children with muscular dystrophy can be overcome.

15 Aug 2005

Complications from angioplasty much lower among patients whose doctors perform a large number of those procedures each year

Before patients get their clogged heart arteries re-opened, they may want to ask their doctor just how many such procedures he or she has done, a new study finds. The answer may make a big difference in each patient's risk of suffering a major setback before leaving the hospital.

15 Aug 2005

Canary Database - animal diseases as early warning system for emerging human diseases

Yale School of Medicine has launched a state-of-the-art database funded in part by the National Library of Medicine, called the Canary Database, containing scientific evidence about how animal disease events can be an early warning system for emerging human diseases.

15 Aug 2005

Immune system more concerned with damage detected than foreign invaders, such as viruses

A well-respected researcher who is now a chief of an immunology laboratory of the National Institutes of Health (NIH) has rocked the boat in the past few years for the experts in the understanding of the autoimmune system.

15 Aug 2005

Psychiatric disorders represent an independent risk factor for delay in cancer diagnosis

Patients with psychiatric disorders are diagnosed with esophageal cancer much later and at a more advanced stage than patients with no psychiatric diagnosis, according to a study conducted by researchers in the Oregon Health & Science University Digestive Health Center.

15 Aug 2005

Lyme disease prevention study in 21 Connecticut communities

Researchers at the Emerging Infections Program (EIP) at Yale School of Medicine in partnership with the Connecticut Department of Public Health and the Centers for Disease Control and Prevention have launched a Lyme disease prevention study in 21 Connecticut communities.

15 Aug 2005

Effects of estrogen on heart disease prevention

Researchers at Yale School of Medicine and seven other national institutions are recruiting patients to participate in the Kronos Early Estrogen Prevention Study (KEEPS) to look at the effects of estrogen on heart disease prevention.

15 Aug 2005

Abbott receives European approval to market Humira

Abbott has announced that it has received approval from the European Commission to market Humira (adalimumab) as a treatment for psoriatic arthritis and early rheumatoid arthritis (RA) in Europe.

15 Aug 2005

Old-fashioned methods best at getting rid of head lice in children

Old-fashioned methods of getting rid of head lice in children are far more effective than current chemical treatments, researchers revealed recently.

15 Aug 2005

New study shows testosterone treatment linked to prostate cancer

Researchers in the United States say that prostate cancer developed in 20 men within months to a few years after they began testosterone supplementation, to correct a deficiency of the hormone.

15 Aug 2005

$Diabetics who require surgery for ankle fractures fare worse than non-diabetics after surgery$

Diabetics who require surgery for ankle fractures fare worse than non-diabetics after surgery

In the largest analysis of its kind, Duke University Medical Center researchers have found that patients with diabetes who require surgery for ankle fractures have significantly higher rates of complications and higher hospital costs compared to non-diabetic patients.

15 Aug 2005

Electron-beam computed tomography best for evaluating adults with congenital defects in the heart arteries

Electron-beam computed tomography (EBCT) is more accurate than conventional catheter angiography for identifying which adult patients face the greatest risk of sudden death from congenital abnormalities in the arteries supplying blood to the heart, according to a study in the September 2005 issue of Catheterization and Cardiovascular Interventions: Journal of the Society for Cardiovascular Angiography and Interventions.

13 Aug 2005

DNA chip technology helps with discovery of new type 2 diabetes gene

In a new study appearing in the August 12 issue of the journal Cell, the investigators first identified genes that were altered in their level of expression in islets isolated from people with type 2 diabetes.

13 Aug 2005

Early menstruation is not by itself a risk factor for later obesity

Although overweight girls are more likely to start their periods earlier than their peers who are at or below normal weight, early menstruation is not by itself a risk factor for later obesity, according to a long-term study released this week.

13 Aug 2005

New gene technique useful for identifying genes and drug targets for diseases such as cancers and diabetes

A collaborative project between American and Chinese researchers developed a way to study the function of genes in mice and man by using a moveable genetic element from moths, according to a report in the journal Cell.

13 Aug 2005

How negatively charged lipids stick to negatively charged DNA and self-organize into structures

Scientists studying the structure and interaction of negatively charged lipids and DNA molecules have created a "cookbook" for a class of nontoxic DNA delivery systems that will assist doctors and clinicians in the safe and effective delivery of genetic medicine.

13 Aug 2005

Researchers have found a signal that could lead to earlier detection and treatment of ovarian cancer

The Penn State team of scientists led by principal investigator Kathleen M. Mulder, Ph.D., professor of pharmacology, and working in conjunction with a researcher from the Center for Cancer Research, National Cancer Institute in Bethesda, Md., studied "km23," a protein that helps to direct protein traffic in the cell.

13 Aug 2005

Avian influenza prevention activities should include better management practices in farms

Wildlife health experts from the Bronx Zoo-based Wildlife Conservation Society (WCS) warn that efforts to control the spread of avian flu across Asia and beyond must focus on better management practices on farms and in markets.

13 Aug 2005

Oxytocin and ingestive behavior

More than 15 years ago Edward Stricker and Joseph Verbalis reported that oxytocin (OT) is involved in the neural control of food and salt intake in adult rats. Linda Rinaman at the University of Pittsburgh is investigating the anatomical organization of this system, and also is taking a developmental approach to determine how OT modulates eating and digestion.

11 Aug 2005

Pre-mRNA that codes for inflammatory protein identified

In a discovery that upends a longstanding tenet of human biology, University of Utah School of Medicine researchers have shown that a key process in gene regulation can occur in human platelets, unique cells that are unusual because they don't have a nucleus (anucleate).

11 Aug 2005

Medicine News and Research

Gene therapy success for the treatment of congenital muscular dystrophy (CMD) in mice

Complications from angioplasty much lower among patients whose doctors perform a large number of those procedures each year

Canary Database - animal diseases as early warning system for emerging human diseases

Immune system more concerned with damage detected than foreign invaders, such as viruses

Psychiatric disorders represent an independent risk factor for delay in cancer diagnosis

Lyme disease prevention study in 21 Connecticut communities

Effects of estrogen on heart disease prevention

Abbott receives European approval to market Humira

Old-fashioned methods best at getting rid of head lice in children

New study shows testosterone treatment linked to prostate cancer

Diabetics who require surgery for ankle fractures fare worse than non-diabetics after surgery

Electron-beam computed tomography best for evaluating adults with congenital defects in the heart arteries

DNA chip technology helps with discovery of new type 2 diabetes gene

Early menstruation is not by itself a risk factor for later obesity

New gene technique useful for identifying genes and drug targets for diseases such as cancers and diabetes

How negatively charged lipids stick to negatively charged DNA and self-organize into structures

Researchers have found a signal that could lead to earlier detection and treatment of ovarian cancer

Avian influenza prevention activities should include better management practices in farms

Oxytocin and ingestive behavior

Pre-mRNA that codes for inflammatory protein identified

Everything there is to know about biosimilars eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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