Amino Acid News and Research

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Amino Acid is one of several molecules that join together to form proteins. There are 20 common amino acids found in proteins.

Where did Omicron's unique spike gene insertion originate?

In a recent study posted to the medRxiv* pre-print server, scientists at nference Labs investigated the origin of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) new variant of concern (VOC) Omicron's unique spike (S) gene insertion ins214EPE.

8 Jun 2022

A new coronavirus found in Swedish bank voles

Researchers report the discovery of the Gimso virus, a novel betacoronavirus in a bank vole from Grimso, Sweden

7 Jun 2022

How do viruses evolve to infect new hosts?

Researchers discuss how protein thermostability prevents the misfolding of viral proteins from being heated.

7 Jun 2022

De novo-designed mini-protein against SARS-CoV-2

Researchers characterized truncated forms of LCB1, a de novo-designed mini-protein, against SARS-CoV-2.

7 Jun 2022

New method to combat malaria turns the disease against itself

A new method to combat malaria which sees the disease turn against itself could offer an effective treatment for the hundreds of millions of people infected globally each year, as the efficacy of current antimalarial drugs weakens.

3 Jun 2022

A system for detecting emerging SARS-CoV-2 variants

An article published in the journal Nature Medicine examines the unpredictable evolution of the ongoing COVID-19 pandemic.

2 Jun 2022

UH expert in lupus reports two new discoveries

Two separate findings by a University of Houston nationally recognized expert in systemic lupus erythematosus (SLE or lupus), a chronic autoimmune disease that affects multiple organs including the kidneys, skin, joints and heart, are being reported in scientific and medical journals.

2 Jun 2022

Phylogenomic characterization of the first genome sequences of the monkeypox virus outbreak variant

Researchers characterized infections caused by the monkeypox virus (MPXV).

2 Jun 2022

Structural and biochemical traits of main protease-mediated SARS-CoV-2 polyprotein processing

A recent article illustrated the structural and biochemical characteristics of the processing of SARS-CoV-2 polyproteins by Mpro.

1 Jun 2022

Study shows the SARS-CoV-2 accessory protein ORF7a inhibits HLA-I surface expression levels in human cells

Researchers identified a single viral gene product, the accessory factor ORF7a, facilitating SARS-CoV-2 immune evasion by downregulating the surface expression of MHC class I molecules.

1 Jun 2022

Sarbecovirus open reading frame 7a suppresses major histocompatibility complex-I antigen presentation

Researchers demonstrated the sarbecovirus open reading frame 7a (ORF7a)-induced hindrance of the antigen presentation by the major histocompatibility complex class I (MHC-I) in hosts.

30 May 2022

Researchers report the case of a non-vaccinated patient coinfected with SARS-CoV-2 Omicron BA.1 and BA.2

A recent study published in The Lancet Microbe described the case of a non-vaccinated female coinfected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.1 and BA.2 subvariants.

30 May 2022

Immunogenicity predictions reveal SARS-CoV-2 CD8+ T-cell epitopes

In a recent study posted to the bioRxiv* pre-print server, researchers identified several new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epitopes displayed on human leukocyte antigens class I (HLA-I) molecules.

26 May 2022

A 6.4 million genome analysis predicts dominant SARS-CoV-2 variants

In this new study in the journal Science, researchers have developed a hierarchical Bayesian regression model, named, PyR0, which can analyze the complete set of publicly available SARS-CoV-2 genomes.

26 May 2022

Cryogenic electron microscopy used to determine the structure of fungal ribosome

Most people carry the fungus Candida albicans on their bodies, without this causing many problems. However, a systemic infection with this fungus is dangerous and difficult to treat.

25 May 2022

The impact of SARS-CoV-2 nucleocapsid protein mutations on the performance of rapid antigen tests

The study findings showed that the rapid antigen tests with the DMS approach could accurately identify antibody escape mutations in the SARS-CoV-2 N protein.

24 May 2022

The design of immunogens for the SARS-CoV-2 spike protein using structure-guided epitope grafting and scaffolding methods

Researchers designed an efficient vaccine design against SARS-CoV-2 infections.

23 May 2022

Study demonstrates that ATV006 is orally bioavailable and has potent efficacy against SARS-CoV-2

A new study has revealed that ATV006, which is a 5′-hydroxyl-isobutyryl prodrug, possesses extraordinary oral pharmaco-kinetic (PK) profiles in rats and cynomolgus monkeys and exhibited significant antiviral activity against ancestral SARS-COV-2 strain as well as VOCs.

20 May 2022

Exploring cross-neutralizing anti-SARS-CoV-2 antibody responses among the general population

Researchers performed a molecular analysis of cross-reactive antibodies targeted against the receptor-binding domain of SARS-CoV-2 strains among the general population.

20 May 2022

Kyunurenic acid in cardiovascular therapy

In a recent study posted to the bioRxiv* preprint server, researchers assessed the impact of kynurenic acid on ischemic damage to the heart.

19 May 2022

Amino Acid News and Research

Further Reading

Where did Omicron's unique spike gene insertion originate?

A new coronavirus found in Swedish bank voles

How do viruses evolve to infect new hosts?

De novo-designed mini-protein against SARS-CoV-2

New method to combat malaria turns the disease against itself

A system for detecting emerging SARS-CoV-2 variants

UH expert in lupus reports two new discoveries

Phylogenomic characterization of the first genome sequences of the monkeypox virus outbreak variant

Structural and biochemical traits of main protease-mediated SARS-CoV-2 polyprotein processing

Study shows the SARS-CoV-2 accessory protein ORF7a inhibits HLA-I surface expression levels in human cells

Sarbecovirus open reading frame 7a suppresses major histocompatibility complex-I antigen presentation

Researchers report the case of a non-vaccinated patient coinfected with SARS-CoV-2 Omicron BA.1 and BA.2

Immunogenicity predictions reveal SARS-CoV-2 CD8+ T-cell epitopes

A 6.4 million genome analysis predicts dominant SARS-CoV-2 variants

Cryogenic electron microscopy used to determine the structure of fungal ribosome

The impact of SARS-CoV-2 nucleocapsid protein mutations on the performance of rapid antigen tests

The design of immunogens for the SARS-CoV-2 spike protein using structure-guided epitope grafting and scaffolding methods

Study demonstrates that ATV006 is orally bioavailable and has potent efficacy against SARS-CoV-2

Exploring cross-neutralizing anti-SARS-CoV-2 antibody responses among the general population

Kyunurenic acid in cardiovascular therapy

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