Immune System News and Research

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AI analysis of biopsy slides predicts rectal cancer treatment response

Artificial intelligence (AI) can predict how well patients with rectal cancer will respond to treatment by analyzing standard tissue samples taken during diagnosis, finds a new study from researchers at UCL and UCLH.

19 Nov 2025

Breakthrough in FcγRI inhibition opens path to safer autoimmune therapies

An international research group directed by UMC Utrecht have developed and characterized two first-in-class antibodies that specifically block the high-affinity IgG receptor FcγRI.

19 Nov 2025

Blood group A linked to a higher risk of primary biliary cholangitis

Findings indicate blood group A elevates the risk of primary biliary cholangitis, suggesting ABO group analysis could aid in autoimmune liver disease diagnosis.

19 Nov 2025

New AI investment aims to accelerate the search for an effective HIV vaccine

As of 2024, over 40 million people in the world are diagnosed with human immunodeficiency virus (HIV)-a chronic, life-threatening infection that remains one of the leading global causes of death.

18 Nov 2025

New transplant approach resets the immune system to stop Type 1 diabetes

A combination blood stem cell and pancreatic islet cell transplant from an immunologically mismatched donor completely prevented or cured Type 1 diabetes in mice in a study by Stanford Medicine researchers.

18 Nov 2025

Early immunotherapy shows higher response in advanced basal cell carcinoma

A new study led by researchers at the Johns Hopkins Kimmel Cancer Center found that patients with advanced basal cell carcinoma (BCC) may benefit from receiving immunotherapy earlier in the course of treatment.

18 Nov 2025

New light-based technology arranges cellular messengers with unprecedented precision

In stunning new time-lapse videos, biological nanoparticles scoot and flit across a starry field of glowing dots. Guided by the invisible chemistry of attraction, these microscopic travelers eventually group together to form perfectly round, glowing circles on a black surface.

18 Nov 2025

Study identifies iron dysregulation in the spleen as a driver of immune aging

Researchers at the Technion – Israel Institute of Technology Faculty of Biology have identified a unique mechanism involved in the aging of the immune system – along with a framework for enhancing its function in older individuals.

18 Nov 2025

Researchers identify key differences between two subtypes of chronic lymphocytic leukemia

Researchers at the University of Eastern Finland and their international collaborators have identified key developmental and molecular differences between the two main subtypes of chronic lymphocytic leukemia, CLL.

18 Nov 2025

T cells drive vaccine effectiveness against porcine reproductive and respiratory syndrome virus

A new study shows that the effectiveness of current vaccines against porcine reproductive and respiratory syndrome virus (PRRSV) is due to the response of T cells against the disease, rather than the production of antibodies.

17 Nov 2025

Researchers develop novel tool to identify pregnant women at high risk for having a preterm birth

Researchers at NYU and partners within the International Healthy Outcomes of Pregnancy for Everyone (HOPE) Consortium have developed a novel tool, the Preterm Birth Actionable Risk Index (PTB-ARIx), designed to identify pregnant individuals at high risk for having a preterm birth (PTB, or delivery before 37 weeks).

17 Nov 2025

UCI Health launches clinical trial to test investigational cell therapy for lupus

UCI Health has opened a clinical trial to test an investigational cell therapy for lupus with the potential to give patients long-term remission of symptoms.

17 Nov 2025

Red meat raises inflammation marker CRP in clinical trials

The review analyzes red meat's effects on inflammatory biomarkers, revealing significant associations with CRP in specific adult subgroups and dietary contexts.

17 Nov 2025

Study uncovers how tumors exploit a molecular signal to exhaust T cells

A new study has discovered a molecular signal that tumors exploit to exhaust the T cells meant to destroy them-and how silencing that signal could revive the body's immunity.

17 Nov 2025

Gut microbes may fuel allergic rhinitis symptoms

The study identifies gut microbiome alterations in allergic rhinitis, suggesting a gut-nose axis that could inform new treatment approaches for this condition.

17 Nov 2025

New insights into periodontitis reveal gender-specific inflammatory mechanisms

A study out of the University of North Carolina at Chapel Hill has unveiled new insights into the inflammatory processes behind periodontitis, a common and debilitating gum disease. Research conducted by UNC Adams School of Dentistry's Julie Marchesan, DDS, PhD, and UNC School of Medicine's Jenny Y. Ting, PhD, found that a part of the immune system called the inflammasome plays a key role in disease development, and that blocking this system prevents bone resorption only in males.

14 Nov 2025

Enhancing the cancer-immunity cycle through innovative vaccines

Therapeutic cancer vaccines have experienced a remarkable resurgence over the past decade, representing a paradigm shift in oncology toward harnessing the immune system's intrinsic ability to combat malignancies.

14 Nov 2025

Cesarean births do not raise infant allergy risk in major Japanese cohort study

In a large Japanese birth cohort, cesarean delivery was not linked to higher risks of eczema, wheezing, atopic dermatitis, or asthma in infants at one year of age. Emergency cesarean delivery was even associated with a modest reduction in eczema, suggesting that mode of birth alone may not drive early-life allergic disease.

13 Nov 2025

Scientists map the genetic control system behind FOXP3 in immune cells

The immune system faces a delicate balancing act: it must be aggressive enough to fight infections and cancer, yet restrained enough to avoid attacking the body's own tissues.

13 Nov 2025

Lymphoma resistance mechanisms and future therapies

A new review was published in Volume 12 of Oncoscience on October 13, 2025, titled "Targeted therapies and resistance mechanisms in lymphoma: Current landscape and emerging solutions."

13 Nov 2025