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Obesity may negatively affect kidney function in women with type 2 diabetes

Obesity may negatively affect kidneys function in people with type 2 diabetes, particularly in women, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

22 Feb 2022

New approach for extensive screening of monoclonal antibody clones against multiple myeloma cells

Multiple myeloma (MM) is a largely incurable cancer of plasma cells with an extremely poor prognosis. However, investigators from Japan have recently found that a common component of amino acid transporters, CD98 heavy chain, represents an effective monoclonal antibody target in treating MM.

22 Feb 2022

Discovery could lead to new treatment approach for people with alcohol-associated liver disease

Investigators at Cedars-Sinai have uncovered a new pathway that helps explain how consuming too much alcohol causes damage to the liver, specifically mitochondrial dysfunction in alcohol-associated liver disease.

22 Feb 2022

A blood test proves to be highly accurate in detecting early signs of Alzheimer's disease

A blood test developed at Washington University School of Medicine in St. Louis has proven highly accurate in detecting early signs of Alzheimer's disease in a study involving nearly 500 patients from across three continents, providing further evidence that the test should be considered for routine screening and diagnosis.

22 Feb 2022

Cellular automata imaging-based classification of SARS-CoV-2 variants

A new preprint classified and grouped SARS-CoV-2 variants based on their cellular automata imaging images and Hamming distances, to determine viral evolutions.

22 Feb 2022

SARS-CoV-2 Omicron variant rapidly takes over Delta viral strain in Norwegian households

Researchers compared the secondary attack rates SARS-CoV-2 Omicron and Delta variants of concern in Norwegian households.

22 Feb 2022

Study provides a potent biparatopic antibody against all SARS-CoV-2 variants of concern

Researchers demonstrated the potent neutralization of SARS-CoV-2 VOCs, including Omicron by the biparatopic human heavy chain variable domain.

22 Feb 2022

Widely utilized SARS-CoV-2 rapid antigen detection tests continue to perform as expected despite Omicron mutations

A recent study evaluated the performance of three at-home COVID-19 rapid antigen tests commonly used in the US against the SARS-CoV-2 Omicron variant.

22 Feb 2022

Lung microbiome alterations and secondary-infections in lethal COVID-19

Researchers examined how an interplay of host and microbial factors weakened immunity leading to secondary infections in COVID-19-infected individuals.

22 Feb 2022

Study suggests anti-SARS-CoV-2 antibodies may persist lifelong post-infection

Researchers attempted to delineate the duration and stability of anti-SARS-CoV-2 antibodies in patients who had recovered from the COVID-19 infection.

22 Feb 2022

Spectrum of autoantibodies linked to autoimmune diseases in patients with different COVID-19 clinical outcomes

A broad evaluation of autoimmune disease-associated autoantibodies that have been observed in COVID-19 patients was performed.

22 Feb 2022

Time-based sensitivity of COVID-19 serological testing

In a recent study under consideration at Scientific Reports and posted to the Research Square* preprint server, researchers evaluated the impact of time on the sensitivity of four severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) serological assays using samples from the coronavirus disease 2019 (COVID-19) staff testing of antibody responses study(Co-Stars) in the United Kingdom (UK).

22 Feb 2022

An abundance of SARS-CoV-2-like viruses in hunted wild animals traded in China

New research published in the journal Cell assesses the viromes of 18 different species of game animals across China to predict potential pathogens similar to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that could infect human populations.

22 Feb 2022

Research explains how SARS-CoV-2 variants evade some antibodies

A recent study published in the iScience Journal assessed the influence of new variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on coronavirus disease 2019 (COVID-19) infectivity and viral neutralization.

22 Feb 2022

Research shows the impact of accessory genes deletion in SARS-CoV-2 evolution

In a recent study published in the journal PLoS ONE, researchers investigated the effect of genetic variability based on accessory gene deletions on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission and the clinical severity of coronavirus disease 2019 (COVID-19).

22 Feb 2022

Protein C News and Research

Obesity may negatively affect kidney function in women with type 2 diabetes

New approach for extensive screening of monoclonal antibody clones against multiple myeloma cells

Discovery could lead to new treatment approach for people with alcohol-associated liver disease

A blood test proves to be highly accurate in detecting early signs of Alzheimer's disease

Cellular automata imaging-based classification of SARS-CoV-2 variants

SARS-CoV-2 Omicron variant rapidly takes over Delta viral strain in Norwegian households

Study provides a potent biparatopic antibody against all SARS-CoV-2 variants of concern

Widely utilized SARS-CoV-2 rapid antigen detection tests continue to perform as expected despite Omicron mutations

Lung microbiome alterations and secondary-infections in lethal COVID-19

Study suggests anti-SARS-CoV-2 antibodies may persist lifelong post-infection

Spectrum of autoantibodies linked to autoimmune diseases in patients with different COVID-19 clinical outcomes

Time-based sensitivity of COVID-19 serological testing

An abundance of SARS-CoV-2-like viruses in hunted wild animals traded in China

Research explains how SARS-CoV-2 variants evade some antibodies

Research shows the impact of accessory genes deletion in SARS-CoV-2 evolution

Using IgG antibody assay to Identify natural SARS-CoV-2 infection in vaccinees

Broad-spectrum antiviral activity of picolinic acid against SARS-CoV-2 and Influenza A virus

Novel ACE2-blocking antibody protects against all SARS-CoV-2 VOCs

Study reports potently neutralizing mucosal IgA in saliva of BNT162b2 vaccine recipients

Researchers unravel essential final steps in the production of mRNA

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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