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Furin cleavage site crucial in SARS-CoV-2 for viral transmission in ferrets, finds study

Researchers based at Imperial College London, UK, have recently highlighted the effects of these deleterious CS mutations through a ferret animal model, demonstrating that furin cleavage sites are a necessary component in the virus’ ability to replicate.

30 Apr 2021

Vaccine hesitancy is not a barrier to vaccination efforts, says study

A team of researchers from the USA, Germany and Norway recently found that the main barrier to vaccination is not vaccine hesitancy but a supply shortage and unequal distribution of the vaccines themselves.

30 Apr 2021

Hepatitis C antivirals synergize with remdesivir to inhibit SARS-CoV-2 in vitro

A new study sheds light on the potential of drug combinations to stem viral transmission and treat patients with COVID-19. It also shows that four drugs used to treat hepatitis C synergize with remdesivir to make it up to ten times more effective at inhibiting SARS-CoV-2 in cell cultures.

30 Apr 2021

Could portable air filters promote clearance of SARS-CoV-2-contaminated aerosols indoors?

A new study shows that inexpensive portable air cleaners may boost the removal of aerosols containing the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from indoor spaces by as much as three times, compared to conventional Heating, Ventilation, and Air Conditioning (HVAC) systems.

30 Apr 2021

Monitoring O2 and CO2 Using Benchtop Bioreactors

Discover how to monitor O2 and CO2 Using Benchtop Bioreactors.

From Thermo Fisher Scientific – Pharmaceutical and Biopharmaceutical Solutions 30 Apr 2021

Delayed antibiotic prescribing unlikely to lead to poorer symptom control

Delayed antibiotic prescribing is a safe and effective strategy for most patients with respiratory tract infections, finds an analysis of patient data published by The BMJ today.

30 Apr 2021

New study reveals mechanisms that result in lethal COVID-19

A new study is drawing the most detailed picture yet of SARS-CoV-2 infection in the lung, revealing mechanisms that result in lethal COVID-19, and may explain long-term complications and show how COVID-19 differs from other infectious diseases.

30 Apr 2021

People living with a child attending in-person schooling have high risk of COVID-19

People living with a child who attends school in-person have an increased risk of reporting evidence of COVID-19, but teacher masking, symptom screening, and other mitigation measures in schools may be able to minimize that excess risk, suggests a study led by researchers at the Johns Hopkins Bloomberg School of Public Health.

30 Apr 2021

Study highlights significant gap in evidence related to effectiveness of portable air filters in reducing COVID-19

Considerable gap in evidence around whether portable air filters reduce the incidence of COVID-19 and other respiratory infections.

30 Apr 2021

Human to animal transmission of SARS-CoV-2 in households is common

Coronaviruses are seen in multiple mammalian species. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the COVID-19 pandemic, is said to have passed to humans from a mammalian source and to have originated from an animal reservoir as a zoonotic pathogen.

29 Apr 2021

Monoclonal antibody CT-P59 shows preclinical efficacy against South African SARS-CoV-2 variant

Researchers in the Republic of Korea (South Korea), The Netherlands, and South Africa have demonstrated the potential of the monoclonal antibody CT-P59 as an effective therapeutic for coronavirus disease 2019 (COVID-19) caused by the South African B.1.351 variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

29 Apr 2021

"COVID-19 diarrhea" depends on inflammatory response that is part of the disease

Researchers in the United States have provided important insights into the pathophysiology of diarrhea that occurs in some cases of coronavirus disease 2019 (COVID-19).

29 Apr 2021

Study finds low risk of infection in babies born to mothers tested positive for SARS-CoV-2

Researchers at Karolinska Institutet and the Public Health Agency of Sweden have studied newborn babies whose mothers tested positive for SARS-CoV-2 during pregnancy or childbirth.

29 Apr 2021

Touching contaminated surfaces can transfer SARS-CoV-2 to skin, finds study

Using artificial skin, researchers found that touching surfaces contaminated with SARS-CoV-2 can lead to transfer of virus to the skin.

29 Apr 2021

Researchers characterize a large set of therapeutic antibodies against SARS-CoV-2 variants

A team of scientists from A-Alpha Bio., USA, has recently conducted a large-scale screening of 33 therapeutic antibodies to examine their binding affinity to a number of SARS-CoV-2 variants. The team analyzed the impact of potential mutations in the spike RBD on antibody efficacy.

29 Apr 2021

Is Hong Kong’s fourth wave of COVID-19 due to the Q57H SARS-CoV-2 variant?

A recent article in the Centers for Disease Control and Prevention (CDC)’s Emerging Infectious Diseases reveals that the last of these was probably due to the introduction of a new variant from Nepal. This novel variant had been circulating in the community for about a month before the last outbreak was reported.

29 Apr 2021

Risk factors for long COVID-19 in children

A new study describes the risk factors and outcomes of “long COVID-19” in a cohort of children who were hospitalized with COVID-19.

29 Apr 2021

Study of 180 breastfeeding mothers after mRNA COVID-19 vaccination

Vaccines against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19, were developed at an unprecedented pace. To date, more than 1 billion vaccine doses have been administered worldwide, many of which messenger RNA (mRNA) based.

29 Apr 2021

New European research network addresses the effects of plastic particles on human health

Researching the effects of plastic particles on the human body and developing a health policy strategy for assessing the resulting risks is the goal of the new European research network PlasticsFatE. The University of Bayreuth, together with 26 other universities, institutes, and organizations from ten EU member states, is participating in the project.

29 Apr 2021

Long COVID also affects children, study finds

Older children and children with allergies or asthma were found to have greater odds of having persistent symptoms even months after recovery.

28 Apr 2021

Respiratory News and Research

Furin cleavage site crucial in SARS-CoV-2 for viral transmission in ferrets, finds study

Vaccine hesitancy is not a barrier to vaccination efforts, says study

Hepatitis C antivirals synergize with remdesivir to inhibit SARS-CoV-2 in vitro

Could portable air filters promote clearance of SARS-CoV-2-contaminated aerosols indoors?

Monitoring O2 and CO2 Using Benchtop Bioreactors

Delayed antibiotic prescribing unlikely to lead to poorer symptom control

New study reveals mechanisms that result in lethal COVID-19

People living with a child attending in-person schooling have high risk of COVID-19

Study highlights significant gap in evidence related to effectiveness of portable air filters in reducing COVID-19

Human to animal transmission of SARS-CoV-2 in households is common

Monoclonal antibody CT-P59 shows preclinical efficacy against South African SARS-CoV-2 variant

"COVID-19 diarrhea" depends on inflammatory response that is part of the disease

Study finds low risk of infection in babies born to mothers tested positive for SARS-CoV-2

Touching contaminated surfaces can transfer SARS-CoV-2 to skin, finds study

Researchers characterize a large set of therapeutic antibodies against SARS-CoV-2 variants

Is Hong Kong’s fourth wave of COVID-19 due to the Q57H SARS-CoV-2 variant?

Risk factors for long COVID-19 in children

Study of 180 breastfeeding mothers after mRNA COVID-19 vaccination

New European research network addresses the effects of plastic particles on human health

Long COVID also affects children, study finds

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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