Genetic News and Research

RSS

Frameshift deletion mutation in ORF7a may provide fitness advantage to Australia's SARS-CoV-2 delta variants

A team of scientists from Australia has recently identified a frameshift deletion mutation in ORF7a of the delta variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The mutation results in the production of a truncated peptide with altered functionality. The study is currently available on the medRxiv* preprint server while awaiting peer review.

24 Aug 2021

Study suggests a novel therapeutic target to reverse lung fibrosis

Researchers have reversed lung fibrosis in a mouse model of idiopathic pulmonary fibrosis, or IPF, as reported in a study published in the journal Cell Death and Differentiation.

24 Aug 2021

Study pinpoints an enzyme with a significant impact on SARS-CoV-2 replication

By applying a systems biology approach, a recent bioRxiv* preprint research paper by scientists from the Icahn School of Medicine at Mount Sinai in New York unveils interactions between the severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) and p38 mitogen-activated protein kinase (MAPK) pathway responsible for regulating the expression of crucial inflammatory mediators in human lung epithelial cells.

23 Aug 2021

Rice bioengineer receives Trailblazer Award to develop technology for reprogramming immune cells

Viruses come in many forms, and Rice University bioengineer Isaac Hilton has long been fascinated by the kind that take control of cells without rewriting their genetic code.

23 Aug 2021

Study suggests algorithm may help optimize future COVID-19 vaccine design

Scientists predict the COVID-19 pandemic is on its way to becoming endemic. The rising spread of COVID-19 variants such as Delta has helped infect unvaccinated and some vaccinated individuals. COVID-19 vaccines continue to be the best way to protect against severe illness and death, but there may be a need for vaccines to protect against a specific variant.

23 Aug 2021

Researchers identify a brief window of opportunity to prevent NF1-associated optic pathway glioma

Researchers at Children's National Hospital identified a vulnerability in a developmental signaling pathway that can be hijacked to drive pediatric low-grade glioma (pLGG) formation, according to a pre-clinical study published in Developmental Cell.

23 Aug 2021

Scientists develop a scalable method to harvest exosomes from unpasteurized cow's milk

Exosomes are nano-sized biological capsules that cells produce to protect and courier delicate molecules throughout the body.

23 Aug 2021

SARS-CoV-2 alpha variant exhibits enhanced household transmission

In a recent study, the transmission rate of wildtype and the Alpha variant of SARS-CoV-2 through households is tracked.

23 Aug 2021

VALIDATE Network’s TB vaccine work receives $1.5 million funding boost

The Oxford-run VALIDATE Network has received $1.5 million in funding for its tuberculosis vaccine work from the Bill & Melinda Gates Foundation.

23 Aug 2021

FDA-approved antiplatelet drug shows potential as new, low-cost heart failure therapy

Sarpogrelate, an antiplatelet medication, has potential as a new heart failure therapy and, according to researchers, could potentially decrease health care costs associated with cardiovascular disease, according to preliminary animal research presented at the American Heart Association's Basic Cardiovascular Sciences Scientific Sessions 2021.

23 Aug 2021

FDA approves COVID-19 mRNA vaccine that uses fundamental Penn technology

The U.S. Food and Drug Administration has given the first full approval to a COVID-19 mRNA vaccine, which uses modified mRNA technology invented and developed by scientists in the Perelman School of Medicine at the University of Pennsylvania, whose years of research in mRNA science laid a critical piece of the foundation for the largest global vaccination campaign in history.

23 Aug 2021

The emergence and spread of the SARS-CoV-2 Lambda (B.1.621) variant

A new study details the genomic characteristics and descent of a SARS-CoV-2 variant of interest.

23 Aug 2021

Study offers hope for an era of safer chemotherapy in breast cancer

Breast cancer is the deadliest and most common type of cancer in women. The treatment options often require administration of anti-cancer drugs in high doses, as the cells develop resistance towards chemotherapy, leading to painful side effects in patients.

23 Aug 2021

Analysis of seadragon genome offers new insights into its phenotype and sex-determination locus

A study by Prof. LIN Qiang from the South China Sea Institute of Oceanology (SCSIO) of the Chinese Academy of Sciences and his collaborators from Singapore and Germany lifts the veil on seadragons' mysterious looks, and sheds light on a sex-determination locus shared by seadragons and alligator pipefish, both members of the Syngnathidae family.

22 Aug 2021

Stress signal from fat cells could help protect the heart from obesity’s negative consequences

A stress signal received by the heart from fat could help protect against cardiac damage induced by obesity, a new study led by UT Southwestern researchers suggests.

20 Aug 2021

Rice University awarded $4 million CPRIT grant to establish Genetic Design and Engineering Center

Rice University faculty members led by bioengineer Gang Bao have been awarded a $4 million grant by the Cancer Prevention and Research Institute of Texas to establish the Genetic Design and Engineering Center.

20 Aug 2021

Review may help clarify the origins of SARS-CoV-2

Today’s COVID-19 pandemic likely began when an infected animal passed the SARS-CoV-2 virus to a human at a live animal market in Wuhan, China.

20 Aug 2021

Leducq Foundation awards $7 million for vascular malformation research

Luisa Iruela-Arispe, PhD, the Stephen Walter Ranson Professor of Cell Biology and chair of Cell and Developmental Biology, is the North American coordinator for an international collaboration that has received a five-year, $7 million Transatlantic Networks of Excellence Program award from the Leducq Foundation.

20 Aug 2021

New AHA statement provides guidance about cardiovascular genetic testing in children

Cardiovascular genetic testing in children presents unique challenges, requiring pre- and post-test counseling with an individualized approach for families.

20 Aug 2021

3D-printed tumors potentially next step in personalized medicine

Scientists at Tel Aviv University have successfully printed an entire active and viable brain tumor using a three-dimensional or 3D printer for the first time.

20 Aug 2021

Genetic News and Research

Frameshift deletion mutation in ORF7a may provide fitness advantage to Australia's SARS-CoV-2 delta variants

Study suggests a novel therapeutic target to reverse lung fibrosis

Study pinpoints an enzyme with a significant impact on SARS-CoV-2 replication

Rice bioengineer receives Trailblazer Award to develop technology for reprogramming immune cells

Study suggests algorithm may help optimize future COVID-19 vaccine design

Researchers identify a brief window of opportunity to prevent NF1-associated optic pathway glioma

Scientists develop a scalable method to harvest exosomes from unpasteurized cow's milk

SARS-CoV-2 alpha variant exhibits enhanced household transmission

VALIDATE Network’s TB vaccine work receives $1.5 million funding boost

FDA-approved antiplatelet drug shows potential as new, low-cost heart failure therapy

FDA approves COVID-19 mRNA vaccine that uses fundamental Penn technology

The emergence and spread of the SARS-CoV-2 Lambda (B.1.621) variant

Study offers hope for an era of safer chemotherapy in breast cancer

Analysis of seadragon genome offers new insights into its phenotype and sex-determination locus

Stress signal from fat cells could help protect the heart from obesity’s negative consequences

Rice University awarded $4 million CPRIT grant to establish Genetic Design and Engineering Center

Review may help clarify the origins of SARS-CoV-2

Leducq Foundation awards $7 million for vascular malformation research

New AHA statement provides guidance about cardiovascular genetic testing in children

3D-printed tumors potentially next step in personalized medicine

Genetics & Genomics - Second Edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News