Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

APOE ε4 carrier status increases the long-term cognitive decline risk associated with herpes zoster

The long-term subjective cognitive decline risk associated with Herpes zoster infections.

19 Aug 2024

Study links dementia diagnosis rates to geographic location

With new medications on the market or in the works for Alzheimer's disease and other kinds of dementia, a new study suggests that getting the diagnosis needed to access these new treatments may depend on where you live.

16 Aug 2024

Researchers reveal why a diet rich in magnesium is so important for your health

Researchers examined whether magnesium deficiency in the healthy middle-aged Australian population was independently or in combination with increased homocysteine levels associated with in vivo DNA damage.

15 Aug 2024

Untreated high blood pressure linked to higher Alzheimer's risk in older adults

People 60 and older with untreated high blood pressure may have an increased risk of Alzheimer's disease compared to both people who have been or are being treated for high blood pressure as well as people without the chronic condition.

14 Aug 2024

Midlife and early senior years marked by dramatic molecular shifts

If it's ever felt like everything in your body is breaking down at once, that might not be your imagination. A new Stanford Medicine study shows that many of our molecules and microorganisms dramatically rise or fall in number during our 40s and 60s.

14 Aug 2024

Study highlights predictors of cognitive decline in early Alzheimer's disease

Older age, female sex, irregular heart rhythms, and daily activity levels can help to predict how much Alzheimer's Disease patients' cognitive function will decline, and how much they will depend on their caregivers over the next two years.

14 Aug 2024

Australia leads life expectancy among English-speaking nations

Australians outlive their peers in five other high-income English-speaking countries by 1 to 4 years, with most of this advantage seen between ages 45 and 84. Lower death rates from drug and alcohol misuse, treatable cancers, and cardiovascular diseases are key factors.

13 Aug 2024

New research identifies key protein complex in cellular quality control

Anyone who's tried to neatly gather a fitted sheet can tell you: folding is hard. Get it wrong with your laundry and the result can be a crumpled, wrinkled mess of fabric, but when folding fails among the approximately 7,000 proteins with an origami-like complexity that regulate essential cellular functions, the result can lead to one of a multitude of serious diseases ranging from emphysema and cystic fibrosis to Alzheimer's disease.

12 Aug 2024

Beyond neurons: Glial cells identified as key players in Alzheimer's disease

Memory loss, confusion, speech problems – Alzheimer's disease is the most common cause of dementia, affecting about 35 million people worldwide, and the number is growing.

12 Aug 2024

Emory researchers offer a new perspective on the mechanism behind Alzheimer's disease

New findings out of Emory University are challenging existing theories about the origins of Alzheimer's, the leading cause of dementia in the elderly worldwide.

12 Aug 2024

New histone tag discovery offers hope for myelin repair in neurodegenerative diseases

In a groundbreaking study, researchers with the Advanced Science Research Center at the CUNY Graduate Center (CUNY ASRC) have identified a distinct histone tag in adult oligodendrocyte progenitor cells (OPCs) that may pave the way for innovative therapies targeting myelin repair, a critical target for several neurodegenerative and psychiatric disorders, including multiple sclerosis, Alzheimer's disease, and schizophrenia.

12 Aug 2024

New drug GSM-15606 may guard against Alzheimer's risk from air pollution

A new study led by the USC Leonard Davis School of Gerontology shows how feeding mice a drug called GSM-15606 provided protection against air pollution-related increases in proteins linked to Alzheimer's disease.

12 Aug 2024

Type 2 diabetes hinders beta-amyloid clearance and may elevate Alzheimer's risk

People with type 2 diabetes are at increased risk of Alzheimer's disease and other adverse cognitive health issues.

12 Aug 2024

New study links brain cell structures to memory loss in aging and dementia

Researchers assessed whether dendritic spine head diameter in the temporal cortex is a better predictor of episodic memory performance in older adults than synapse quantity, accounting for β amyloid plaques, neurofibrillary tangles, and sex.

12 Aug 2024

New proteomic clock predicts biological age and major health risks across diverse populations

Study developed a proteomic age clock using plasma proteins to accurately predict biological age and associated health risks, offering a robust tool for forecasting age-related diseases and mortality.

11 Aug 2024

Enzyme blockade improves memory updating in older mice

Everyone has moments of forgetfulness from time to time, especially as we get older. But older adults don't just have difficulty remembering new information.

9 Aug 2024

NIH awards $3.5M grant to study link between traumatic brain injury and Alzheimer's

A traumatic brain injury, or TBI, is caused by a contusion to the head that may result in injury to the brain.

8 Aug 2024

Breakthrough molecule reverses Alzheimer's symptoms

In a new study, a molecule identified and synthesized by UCLA Health researchers was shown to restore cognitive functions in mice with symptoms of Alzheimer's disease by effectively jumpstarting the brain's memory circuitry.

8 Aug 2024

Amyloid immunotherapy for early Alzheimer's: Promising but fraught with challenges

Researchers highlighted the complexities of using amyloid immunotherapy for early Alzheimer's disease, discussing its clinical benefits, challenges, and broader health implications. Despite some positive results, concerns over adverse effects, trial biases, and cost hinder widespread adoption.

7 Aug 2024

Researchers identify distinct molecular profiles in Down syndrome

A new study published in Nature Communications by researchers from the Linda Crnic Institute for Down Syndrome (Crnic Institute) at the University of Colorado Anschutz Medical Campus reports a significant breakthrough.

7 Aug 2024