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Penn researchers develop optimized framework for COVID-19 vaccination distribution

Engineering and medical researchers at Penn have developed a groundbreaking framework that can determine the best and most computationally optimized distribution strategy for COVID-19 vaccinations in any given community.

22 Jan 2025

Study uncovers blood signatures linked to Sudden Infant Death Syndrome

New University of Virginia School of Medicine research revealing the fingerprints of Sudden Infant Death Syndrome within blood samples could open the door to simple tests to identify babies at risk.

22 Jan 2025

Study identifies genetic variations linked to allergic sensitization

Humans are continuously exposed to various environmental allergens (antigens), such as pollen, food, and dust mites.

21 Jan 2025

Short-course antibiotics can be a game-changer in tackling ventilator-associated pneumonia

Antibiotic overuse is a key driver in the rise of antimicrobial resistance (AMR), a major global health crisis.

21 Jan 2025

New imaging protocol enhances visualization of rare bone marrow cells

Bone marrow plays a crucial role in maintaining hematopoietic stem cells and bone homeostasis. However, research has been hindered by a lack of effective markers and monoclonal antibodies to accurately identify rare LepR+ stromal cells.

21 Jan 2025

Early pregnancy weight gain contributes to excess fat distribution in fetuses

Fetuses of pregnant people who gained excess weight in the first trimester of pregnancy show signs of excess fat distribution in the upper arm and in the abdomen, according to a study by researchers at the National Institutes of Health.

17 Jan 2025

Cigarette smoke alters immune cell function in the lungs

Cigarette smoking is widespread and deadly, yet our understanding of how cigarette smoke actually causes serious respiratory illnesses is incomplete, which has severely hampered the development of effective treatments.

17 Jan 2025

U.S. launches national plan to tackle Parkinson's disease and related disorders

With support from the U.S. Department of Health and Human Services (HHS) Office of the Assistant Secretary for Health (OASH), the National Institutes of Health (NIH) is leading the implementation of the Dr. Emmanuel Bilirakis and Honorable Jennifer Wexton National Plan to End Parkinson's Act (P.L. 118-66), which was signed into law on July 2, 2024.

17 Jan 2025

Protein CD74 could predict immunotherapy response in bowel cancer

Researchers at the Francis Crick Institute and Barts Cancer Institute, Queen Mary University of London, have shown that the amount of a protein called CD74 can indicate which people with bowel cancer may respond best to immunotherapy.

16 Jan 2025

Immune system changes may predict antipsychotic resistance in schizophrenia Scientis...

Researchers from the National Healthcare Group (NHG)'s Institute of Mental Health (IMH) and Agency for Science, Technology and Research (A*STAR) have made strides in understanding the connection between the immune system and resistance to antipsychotic medications in schizophrenia, using changes in immune cell populations to predict potential treatment resistance and initiate the most appropriate treatment sooner.

16 Jan 2025

Scientists discover how viral infection triggers autoimmune disease

Scientists at the Garvan Institute of Medical Research have discovered how a viral infection causes autoimmune disease, disproving a long-standing theory and opening a promising new approach to developing treatments for autoimmune conditions.

16 Jan 2025

Study unveils role of TLE6 in male sperm development

Infertility is a major global challenge associated with physiological and psychological impact. Genetic mutations that affect early embryonic development, oocyte (egg cell) maturation, and fertilization have recently been studied as causes of infertility.

16 Jan 2025

Revolutionizing missing data management in EHRs with machine learning

Researchers from the National Institute of Health Data Science at Peking University and the Department of Clinical Epidemiology and Biostatistics at Peking University People's Hospital have conducted a comprehensive systematic review evaluating strategies for addressing missing data in electronic health records (EHRs).

16 Jan 2025

Nicotine pouch use among soldiers significantly higher than civilians

American soldiers are 10 times more likely to use nicotine pouches that can cause serious health issues than average American adults, according to a survey of military personnel at Fort Liberty, the largest American military base.

15 Jan 2025

New target identified for potential colorectal cancer treatment

Colorectal cancer (CRC) is a type of cancer that begins in the colon (large intestine) or rectum, which are parts of the digestive system.

15 Jan 2025

Groundbreaking trial finds levofloxacin effective against multidrug-resistant TB

A clinical trial published in the New England Journal of Medicine showed that the oral antibiotic levofloxacin taken once-daily for six months substantially reduced the risk of developing drug-resistant tuberculosis (TB), and almost halved adults' and children's risk of developing multidrug-resistant TB.

15 Jan 2025

Study explores cancer risks of hormonal contraceptives

Many women worry hormonal contraceptives have dangerous side-effects including increased cancer risk. But this perception is often out of proportion with the actual risks.

15 Jan 2025

Uncovering the neurobiological mechanisms of delta opioid receptor agonists

The global burden of anxiety- and depression-related disorders is on the rise. While multiple drugs have been developed to treat these conditions, current medications have several limitations, including slow action and adverse effects with long-term use. This underscores the urgent need for novel, rapidly-acting therapeutic agents with minimal side effects.

15 Jan 2025

Researchers develop computer models to improve antibiotic targeting and minimize resistance

With antibiotic resistance a growing problem, University of Virginia School of Medicine researchers have developed cutting-edge computer models that could give the disease-fighting drugs a laser-like precision to target only specific bacteria in specific parts of the body.

15 Jan 2025

COVID-19 infection linked to increased cases of ME/CFS

New findings from the National Institutes of Health's (NIH) Researching COVID to Enhance Recovery (RECOVER) Initiative suggest that infection with SARS-CoV-2, the virus that causes COVID-19, may be associated with an increase in the number of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) cases.

13 Jan 2025