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Two common Staph bacteria living on human skin exacerbate Netherton syndrome

Netherton syndrome, a rare skin disease caused by a single genetic mutation, is exacerbated by the presence of two common Staphylococcal bacteria living on human skin, one of which was previously thought to only offer protective properties, report University of California San Diego School of Medicine researchers.

3 Mar 2020

A protein critical for wound healing and neural repair following spinal cord injury identified

Plexin-B2, an axon guidance protein in the central nervous system (CNS), plays an important role in wound healing and neural repair following spinal cord injury (SCI), according to research conducted at the Icahn School of Medicine at Mount Sinai and published today in Nature Neuroscience. T

2 Mar 2020

New genetic tool developed to label specific genes in human organoids

Researchers from the group of Hans Clevers at the Hubrecht Institute have developed a new genetic tool to label specific genes in human organoids, or mini organs.

2 Mar 2020

UC Santa Cruz leads collaborative project to develop novel technology for improving wound healing

UC Santa Cruz will lead a collaborative project to develop innovative technology for improving the healing of serious wounds, funded by a contract worth up to $16 million from the Defense Advanced Research Projects Agency.

27 Feb 2020

Harmful levels of metal linked to DNA damage found in the urine of e-cigarette users

Researchers at the University of California, Riverside, have completed a cross-sectional human study that compares biomarkers and metal concentrations in the urine of e-cigarette users, nonsmokers, and cigarette smokers.

20 Feb 2020

Targeting regulatory T cells could boost the effects of cancer immunotherapy

A Ludwig Cancer Research study has identified a mechanism by which regulatory T cells, which suppress immune responses, adapt their metabolism to thrive in the harsh microenvironment of the tumor.

17 Feb 2020

Scientists develop "smart" remote-control bandage for chronic wounds

People with diabetes suffer from chronic and non-healing wounds, often leading to severe infection and, eventually, amputation of the limb. The essential treatment for these wounds is the continuous application of medicines and the regular changing of bandages to prevent infection.

16 Feb 2020

Treating soft tissue sarcoma with shorter radiation treatment found to be safe, effective

A new study led by researchers at the UCLA Jonsson Comprehensive Cancer Center found that treating soft tissue sarcoma with radiation over a significantly shorter period of time is safe, and likely just as effective, as a much longer conventional course of treatment.

13 Feb 2020

'Smart' bandages could facilitate healing of hard-to-treat wounds

Chronic and non-healing wounds--one of the most devastating complications of diabetes and the leading cause of limb amputation--affects millions of Americans each year. Due to the complex nature of these wounds, proper clinical treatment has been limited.

13 Feb 2020

Acid reflux drug may be a promising therapy to reduce preterm birth

Lansoprazole, an over-the-counter acid reflux drug that is often taken by pregnant women, may be a promising therapy to reduce preterm birth, according to a computational drug repurposing study that also tested several of the drugs in mice.

13 Feb 2020

Study highlights trends in hospitalization, outcomes among veterans with critical limb ischemia

Between 2005 and 2014, the number of veterans who were hospitalized, required amputation or died due to critical blockages in leg arteries declined, according to new research published today in Circulation: Cardiovascular Interventions, a journal of the American Heart Association.

13 Feb 2020

Conservative Indiana adopted needle exchanges but still faces local resistance

Back when Cody Gabbard was shooting heroin, his only significant human contact was with others in the throes of addiction, who only cared to see him when he had drugs.

12 Feb 2020

Developmental shape-shifting is key to cancer's ability to spread and evade immune defenses

Just as people tend to become stuck in their ways as they grow older so too do cells. Neurons in the brain don't one day decide to become heart cells; skin cells repair wounds with skin cells rather than kidney cells.

11 Feb 2020

Addressing the complexity of nasal tip contouring

The dramatic shift in how nasal tip surgery is being performed given changes in the intended goals and evolving techniques is highlighted in a Special Communication by and interview with Dean Toriumi, MD, published in the Official Journal of the American Academy of Facial Plastic and Reconstructive Surgery, Facial Plastic Surgery & Aesthetic Medicine, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

11 Feb 2020

New study sheds light on human in vitro organ model research trends

Two distinct approaches are predominantly used to recapitulate physiologically relevant in vitro human organ models.

9 Feb 2020

New wearable patch for remote monitoring of chronic wounds

Graphene Flagship associated member, Grapheal has developed a pioneering wearable patch for the remote monitoring of chronic wounds.

5 Feb 2020

New handheld 3D skin printer accelerates healing of large burn wounds

A new handheld 3D printer can deposit sheets of skin to cover large burn wounds - and its "bio-ink" can accelerate the healing process.

4 Feb 2020

3D-printed scaffolds engraved with grooves hold promise for healing injuries

Who ever said bioengineers can't get their groove on? The Rice University team led by Antonios Mikos says otherwise with its development of a groovy method to seed sophisticated, 3D-printed tissue-engineering scaffolds with living cells to help heal injuries.

4 Feb 2020

Study reveals new strategies to prevent skin scarring

A new study in Burns & Trauma, published by Oxford University Press, reveals promising new strategies to prevent skin scarring after injuries.

4 Feb 2020

Turning stink into therapy for atherosclerosis

In an amusing but amazing turnaround, it seems the most foul-smelling compound on earth, called putrescine, could help relieve chronic inflammation, most importantly in the arterial thickening called atherosclerosis. This discovery is reported in the journal Cell Metabolism in January 2020.

30 Jan 2020