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Midazolam autoinjector may effectively treat status epilepticus

Drug delivery into muscle using an autoinjector, akin to the EpiPen used to treat serious allergic reactions, is faster and may be a more effective way to stop status epilepticus, a prolonged seizure lasting longer than five minutes, according to a study sponsored by the National Institutes of Health. Status epilepticus is a potentially life-threatening emergency that causes 55,000 deaths each year.

16 Feb 2012

UCSF stem cell study suggests novel strategy for heart attack

A UCSF stem cell study conducted in mice suggests a novel strategy for treating damaged cardiac tissue in patients following a heart attack. The approach potentially could improve cardiac function, minimize scar size, lead to the development of new blood vessels - and avoid the risk of tissue rejection.

16 Feb 2012

Deep brain stimulation can also affect respiratory function

Deep brain stimulation (DBS) has become a common treatment for patients with chronic pain or movement disorders. Now a unique set of experiments shows that electrical stimulation in some of the same brain areas can also affect respiratory function, according to a study in the February issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.

16 Feb 2012

U.S. FDA accepts Pfizer's tafamidis NDA for treatment of TTR-FAP

Pfizer Inc. today announced that the U.S. Food and Drug Administration (FDA) has accepted for review the New Drug Application (NDA) for tafamidis meglumine, the company's investigational, novel, oral therapy for the treatment of Transthyretin Familial Amyloid Polyneuropathy.

16 Feb 2012

Researchers identify potent regulator of sensitivity to insulin

Researchers at Washington University School of Medicine in St. Louis have identified a potent regulator of sensitivity to insulin, the hormone that controls blood sugar levels. The new findings may help scientists find better treatments for type 2 diabetes, obesity and other health problems caused by the body's inability to properly regulate blood sugar.

16 Feb 2012

St. Jude Medical to examine cost-effectiveness of FFR-guided therapy in Australia, Asia

St. Jude Medical, Inc., a global medical device company, announced today it will evaluate the incremental cost-effectiveness of Fractional Flow Reserve (FFR)-guided treatment for patients with multivessel coronary artery disease in Japan, China, India, Korea, and Australia.

15 Feb 2012

Heart attack scars mended using stem cells

Researchers from United States have successfully healed the scars caused by a heart attack using stem cells gathered from the patient's own heart. The amount of scar tissue was halved in the small safety trial reported in the Lancet medical journal. The authors said there was also an “unprecedented” increase in new heart muscle.

15 Feb 2012

CMR highly effective in diagnosing life-threatening arrhythmias

New research from Western University, Canada, has demonstrated the benefits of performing Cardiovascular Magnetic Resonance (CMR) in cases where patients have been resuscitated after Sudden Cardiac Death or enter hospital suffering from ventricular arrhythmias.

15 Feb 2012

Kowa announces data of LIVALO vs. Crestor on pharmacodynamics of warfarin

Kowa Pharmaceuticals America, Inc. today announced data assessing the effect of LIVALO (pitavastatin) compared with Crestor (rosuvastatin) on steady-state pharmacodynamics (PD) of warfarin by measuring international normalized ratio (INR) in healthy adult subjects.

14 Feb 2012

New light on treatment targets for potentially life-threatening cardiac arrhythmia conditions

That flutter in your heart may have more to do with the movement of sodium ions than the glance of a certain someone across a crowded room.

14 Feb 2012

Prevention and treatment options are improving long-term outcomes for heart failure

"Despite the increasing number of people affected, the prognosis for patients with heart failure has steadily improved," said Gregg C. Fonarow, M.D, chairman of American Heart Association Hospital Accreditation Science Committee and professor of cardiovascular medicine of the University of California, Los Angeles.

14 Feb 2012

Surgery causes musculoskeletal alterations in breast cancer patients

A research study conducted at the University of Granada -and published in the prestigious American Journal of Physical Medicine and Rehabilitation-has revealed that the surgery performed on breast cancer patients causes musculoskeletal alterations.

14 Feb 2012

Scientists develop mutant zebrafish to study Maple Syrup Urine Disease

In medical research, finding a reliable and cost-effective animal model can greatly enhance success in identifying disease mechanisms and genetic pathways, potentially cutting years off drug testing regimes and development of new treatment strategies.

14 Feb 2012

NTRR completes research and development of new erectile dysfunction treatment

With Neutra Corp.'s Pure Plus weight-loss supplement already in the midst of clinical trials, the company announced today that it has completed research and development of its next product in the Pure Plus line: an all-natural erectile dysfunction (ED) treatment.

13 Feb 2012

RUMC sponsors Nutritional Medicine workshop

Rush University Medical Center is sponsoring a Nutritional Medicine workshop March 15 to 16, 2012, that features internationally-renowned faculty who are leaders in research in nutritional medicine.

13 Feb 2012

Researchers discover a startling feature of early brain development

Researchers at the Salk Institute have discovered a startling feature of early brain development that helps to explain how complex neuron wiring patterns are programmed using just a handful of critical genes. The findings, published February 3 in Cell, may help scientists develop new therapies for neurological disorders, such as amyotrophic lateral sclerosis (ALS), and provide insight into certain cancers.

13 Feb 2012

KSU, St. Michael's receive U.S. patent to use BRCA1 gene for cardiovascular disease

St. Michael's Hospital and King Saud University have received their first joint U.S. patent to use the BRCA1 gene as a therapy for cardiovascular disease.

13 Feb 2012

Research team studies effect of anabolic steroids on body fat

A research team at Luleå University of Technology and Umea University has, in a unique study involving ten Swedish elite lifters who are actively using anabolic steroids, studied the effect of Anabolic steroids on body fat. Swedish elite lifters who use anabolic steroids have more dangerous fat distribution in the body.

12 Feb 2012

Tai chi could benefit Parkinson’s disease patients

A new study found that a six-month program of Tai Chi exercises helped people with various stages of Parkinson's disease improve stability, their ability to walk and reduced the frequency of falls.

12 Feb 2012

New device offers fresh hope for patients with Motor Neurone Disease

Patients suffering from a devastating disease are being given fresh hope through an innovative trial being led by the Sheffield Institute for Translational Neuroscience (SITraN) and Sheffield Teaching Hospitals.

10 Feb 2012