Clinical Trial News and Research

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Vrije University Brussels installs MILabs PET-SPECT-CT-MRI platform for nanobody research

The comprehensive MILabs PET-SPECT-CT-MR preclinical platform combines the best PET-SPECT functional imaging capabilities (sub-half-mm SPECT resolution and sub-mm PET resolution) with high resolution anatomical imaging from an integrated X-ray CT subsystem and/or a compact cryogen free 1.5 T MRI unit

13 Mar 2015

New immunotoxin found to be safe, effective in patients with B-cell malignancies

Almost all patients with a group of blood cancers called B-cell malignancies have two prominent "fingerprints" on the surface of leukemia and lymphoma cancers, called CD22 and CD19, Vallera explained.

13 Mar 2015

'Turbocharged' protein holds promise in hemophilia gene therapy

Using gene therapy to produce a mutant human protein with unusually high blood-clotting power, scientists have successfully treated dogs with the bleeding disorder hemophilia, without triggering an unwanted immune response.

13 Mar 2015

Ember Therapeutics, Mariel Therapeutics sign definitive merger agreement

Ember Therapeutics, Inc., a Boston-based biotechnology company dedicated to the discovery and development of novel obesity and diabetic related therapies, and Mariel Therapeutics, a privately held, New York-based biotechnology company developing targeted therapies for osteoarthritis and kidney fibrosis using Bone Morphogenetic Protein (BMP)-7, jointly announce today that they have entered into a definitive agreement to merge the two companies.

12 Mar 2015

Neuralstem reports top line data from NSI-566 Phase II trial for treatment of ALS

Neuralstem, Inc. announced top line data from the Phase II trial of NSI-566 spinal cord-derived neural stem cells under development for the treatment of amyotrophic lateral sclerosis (ALS). The study met primary safety endpoints. The maximum tolerated dose of 16 million transplanted cells and the surgery was well tolerated.

12 Mar 2015

Washington University researchers develop way to apply light-based therapy to reach deep tumors

Light long has been used to treat cancer. But phototherapy is only effective where light easily can reach, limiting its use to cancers of the skin and in areas accessible with an endoscope, such as the gastrointestinal tract.

12 Mar 2015

Study finding suggests importance of individually-tailored treatment for depression

The most commonly used treatment for the over 14 million Americans who suffer from Major Depressive Disorder is anti-depressant medication. While such medications bring relief to many, current research suggests that one size may not fit all when it comes to treating depression.

12 Mar 2015

Promising new natural treatment for Alzheimer's disease nears clinical trial

A promising new natural treatment for Alzheimer's disease is moving toward clinical trials. This will be a major step forward as there is nothing on the market that slows the progression of Alzheimer's.

12 Mar 2015

Clinical trial examines uncertainty about when to give blood transfusions after cardiac surgery

New research has shown that patients having heart surgery do not benefit if doctors wait until a patient has become substantially anaemic before giving a transfusion.

12 Mar 2015

UTHealth remotely enrolls patients into acute stroke clinical trial with telemedicine method

For the first time in the world, researchers at The University of Texas Health Science Center at Houston were able to enroll patients at other hospitals into an acute stroke clinical trial.

12 Mar 2015

Existing epilepsy drug reverses aMCI in elderly patients at risk for Alzheimer's disease

A novel therapeutic approach for an existing drug reverses a condition in elderly patients who are at high risk for dementia due to Alzheimer's disease, researchers at Johns Hopkins University found.

12 Mar 2015

Early mobility therapy improves outcomes of patients with acute respiratory distress syndrome

Acute respiratory distress syndrome (ARDS) is a life-threatening lung condition that affects approximately 200,000 people a year in the United States and has a higher mortality rate than breast and prostate cancer combined. The condition most often occurs in people who are critically ill or who have significant injuries; those who do survive it often experience profound skeletal muscle weakness.

12 Mar 2015

Fourth patient dosed in Benitec Biopharma's Phase I/IIa hepatitis C trial

Benitec Biopharma, a biopharmaceutical company focused on providing potentially curative therapies with its proprietary gene-silencing technology called ddRNAi or "expressed RNAi," today announced that the fourth patient in the company's Phase I/IIa dose escalation clinical trial of its lead program TT-034 for treating hepatitis C was dosed at the Duke Clinical Research Unit.

11 Mar 2015

New stem cell treatment reverses disability in certain MS patients

A PIONEERING new stem cell treatment ‘rebooting’ the immune system in some multiple sclerosis sufferers is being hailed as an encouraging step forward in the treatment of the disease in sufferers who fail to respond to standard therapies.

11 Mar 2015

Naproxen and omeprazole combination effective in preventing bladder cancer

The anti-inflammatory class of drugs NSAIDs have shown great promise in preventing cancers including colon, esophagus and skin. However, they can increase the risks of heart attacks, ulcers and rare but potentially life-threatening bleeds.

11 Mar 2015

LSDF announces new Matching grants to promote treatments for devastating medical conditions

The Life Sciences Discovery Fund today announced nearly $1 million in Matching grants to two Washington-based companies to promote translation of promising treatments for devastating medical conditions from the laboratory to the commercial marketplace.

11 Mar 2015

New method could lead to improved treatment for NPC patients

Researchers at the University of Birmingham believe that a new method of genetically engineering immune cells could lead to improved treatment of Nasopharyngeal carcinoma (NPC) patients.

11 Mar 2015

Brain tumor experts launch revolutionary fast-track approach to cancer research

Brain tumor experts at Barrow Neurological Institute at Dignity Health St. Joseph's Hospital and Medical Center have launched a revolutionary fast-track approach to cancer research, giving new hope to brain cancer patients.

10 Mar 2015

Chemotherapy, radiation therapy combination improves outcomes for people with low-grade brain cancer

New clinical-trial findings provide further evidence that combining chemotherapy with radiation therapy is the best treatment for people with a low-grade form of brain cancer. The findings come from a phase II study co-led by a researcher at Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute and researchers at the University of Maryland and at London Regional Cancer Program in Ontario, Canada.

10 Mar 2015

InMed, University of Debrecen partner to develop novel therapies to treat ocular allergies

InMed Pharmaceuticals Inc. announces it has formed an exclusive strategic collaboration with the University of Debrecen, Hungary, to develop novel phytocannabinoid-based therapies to treat ocular allergic symptoms.

10 Mar 2015

Clinical Trial News and Research

Vrije University Brussels installs MILabs PET-SPECT-CT-MRI platform for nanobody research

New immunotoxin found to be safe, effective in patients with B-cell malignancies

'Turbocharged' protein holds promise in hemophilia gene therapy

Ember Therapeutics, Mariel Therapeutics sign definitive merger agreement

Neuralstem reports top line data from NSI-566 Phase II trial for treatment of ALS

Washington University researchers develop way to apply light-based therapy to reach deep tumors

Study finding suggests importance of individually-tailored treatment for depression

Promising new natural treatment for Alzheimer's disease nears clinical trial

Clinical trial examines uncertainty about when to give blood transfusions after cardiac surgery

UTHealth remotely enrolls patients into acute stroke clinical trial with telemedicine method

Existing epilepsy drug reverses aMCI in elderly patients at risk for Alzheimer's disease

Early mobility therapy improves outcomes of patients with acute respiratory distress syndrome

Fourth patient dosed in Benitec Biopharma's Phase I/IIa hepatitis C trial

New stem cell treatment reverses disability in certain MS patients

Naproxen and omeprazole combination effective in preventing bladder cancer

LSDF announces new Matching grants to promote treatments for devastating medical conditions

New method could lead to improved treatment for NPC patients

Brain tumor experts launch revolutionary fast-track approach to cancer research

Chemotherapy, radiation therapy combination improves outcomes for people with low-grade brain cancer

InMed, University of Debrecen partner to develop novel therapies to treat ocular allergies

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