Immune System News and Research

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Stem cell-based method selectively targets cancerous tissue while preventing toxic side effects

A stem cell-based method created by University of California, Irvine scientists can selectively target and kill cancerous tissue while preventing some of the toxic side effects of chemotherapy by treating the disease in a more localized way.

27 Jul 2017

HIV transmission among gay partners may be prevented using medication, finds new study

One of the largest studies undertaken has explored the risk of transmitting HIV infection by an HIV infected partner to his non-infected gay partner. Results reveal that HIV positive men who are on medication for HIV that makes their virus load undetectable in blood are not likely to transmit the infection to their non-infected partners.

26 Jul 2017

Study provides fresh insights into how the body detects early signs of cancer

Fresh insights into how cells detect damage to their DNA - a hallmark of cancer - could help explain how the body keeps disease in check.

26 Jul 2017

Research offers explanation for ineffectiveness of checkpoint immunotherapy against bladder cancer

New research offers a possible explanation for why a new type of cancer treatment hasn't been working as expected against bladder cancer.

25 Jul 2017

Researchers discover mechanism that plays key role in development of resistance to immunotherapy

In tumor immunotherapy, the body's own defense system is activated against the tumor cells. However, for the majority of patients, the tumor cells become resistant to the treatments used.

25 Jul 2017

Preclinical study demonstrates efficacy of gene therapy in treatment of Duchenne muscular dystrophy

Researchers from Genethon, the AFM-Telethon laboratory, Inserm (UMR 1089, Nantes) and the University of London (Royal Holloway) demonstrated the efficacy of an innovative gene therapy in the treatment of Duchenne muscular dystrophy.

25 Jul 2017

Cocktail of drugs for HIV patients with advanced immunosuppression reduced deaths by 27%, study shows

A study published in the New England Journal of Medicine on 20th July 2017 suggests that a cocktail of drugs, if provided at the beginning of the HIV therapy, can save over 10,000 lives per year. HIV, which is often diagnosed late, leaves people vulnerable to other diseases by ravaging the immune system.

25 Jul 2017

UC scientists take different approach to investigating how influenza spreads through the lungs

Influenza is a recurring global health threat that, according to the World Health Organization, is responsible for as many as 500,000 deaths every year, most due to influenza pneumonia, or viral pneumonia.

25 Jul 2017

Cellectis wins European patent for CRISPR use in T-cells

Cellectis, a clinical-stage biopharmaceutical company focused on developing immunotherapies based on gene-edited CAR T-cells (UCART), today announced the grant by the European Patent Office of patent No. EP3004337 for the invention of using RNA-guided endonucleases, such as Cas9 or Cpf1 for the genetic engineering of T-cells.

24 Jul 2017

UNC receives $5.6 million from NIH to test therapeutic HIV vaccine

A multidisciplinary research team at the University of North Carolina at Chapel Hill has been awarded more than $5.6 million from the National Institutes of Health to test a therapeutic vaccine in people living with HIV.

24 Jul 2017

Cow immunization may lead to new human vaccines and treatments for HIV, study finds

Antibodies against the Human Immunodeficiency Virus (HIV) have been obtained for the first time by injecting cows with an HIV antigen. This achievement offers promise for the development of anti-HIV treatments or vaccines.

21 Jul 2017

Study: Response to combination immunotherapy in melanoma depends on proportion of immune cells

Whether a melanoma patient will better respond to a single immunotherapy drug or two in combination depends on the abundance of certain white blood cells within their tumors, according to a new study conducted by UC San Francisco researchers joined by physicians from UCSF Health.

20 Jul 2017

Skin-applied microneedle patch boosts immunization to seasonal flu vaccine recipients, study finds

A boosting skin vaccination with a biodegradable microneedle patch and protein constructed from sequences of influenza virus subtypes could improve the effectiveness of conventional influenza vaccines, according to a study led by Georgia State University.

19 Jul 2017

Engineered macrophages invade and engulf tumor cells in mouse models

One reason cancer is so difficult to treat is that it avoids detection by the body. Agents of the immune system are constantly checking the surfaces of cells for chemical signals that say they belong, but cancer cells express the same chemical signals as healthy ones.

19 Jul 2017

Two cell types partner to protect pancreatic tumors from immune attack

Two cell types work together to protect pancreatic tumors from destruction by the immune system. But, blocking this partnership may restore the system's ability to attack these same tumor cells.

19 Jul 2017

Scientists manage to permeate living cells with small antibodies

Scientists at the Technische Universität Darmstadt, Ludwig Maximilians University Munich and the Leibniz Institute for Molecular Pharmacology have managed to introduce tiny antibodies into living cells. The researchers now report on the synthesis and applications for these nanobodies in "Nature Chemistry".

19 Jul 2017

Titanium dioxide nanoparticles can intensify inflammatory reaction in patients with colitis

Titanium dioxide, one of the most-produced nanoparticles worldwide, is being used increasingly in foodstuffs.

19 Jul 2017

Researchers identify new way to increase immune response against cancer and infections

An international research team led by Université de Montréal medical professor Christopher Rudd, director of research in immunology and cell therapy at Maisonneuve-Rosemont Hospital Research Centre, has identified a key new mechanism that regulates the ability of T-cells of the immune system to react against foreign antigens and cancer.

19 Jul 2017

Unique 'Golden Hour' study details ultra-early immune response to trauma

Scientists from the University of Birmingham are carrying out pioneering research as part of a major £10 million study aimed at improving outcomes for patients who have suffered a traumatic injury.

19 Jul 2017

Study shows how omega-3 fatty acids can produce same medicinal qualities as marijuana

Chemical compounds called cannabinoids are found in marijuana and also are produced naturally in the body from omega-3 fatty acids.

18 Jul 2017

Immune System News and Research

Stem cell-based method selectively targets cancerous tissue while preventing toxic side effects

HIV transmission among gay partners may be prevented using medication, finds new study

Study provides fresh insights into how the body detects early signs of cancer

Research offers explanation for ineffectiveness of checkpoint immunotherapy against bladder cancer

Researchers discover mechanism that plays key role in development of resistance to immunotherapy

Preclinical study demonstrates efficacy of gene therapy in treatment of Duchenne muscular dystrophy

Cocktail of drugs for HIV patients with advanced immunosuppression reduced deaths by 27%, study shows

UC scientists take different approach to investigating how influenza spreads through the lungs

Cellectis wins European patent for CRISPR use in T-cells

UNC receives $5.6 million from NIH to test therapeutic HIV vaccine

Cow immunization may lead to new human vaccines and treatments for HIV, study finds

Study: Response to combination immunotherapy in melanoma depends on proportion of immune cells

Skin-applied microneedle patch boosts immunization to seasonal flu vaccine recipients, study finds

Engineered macrophages invade and engulf tumor cells in mouse models

Two cell types partner to protect pancreatic tumors from immune attack

Scientists manage to permeate living cells with small antibodies

Titanium dioxide nanoparticles can intensify inflammatory reaction in patients with colitis

Researchers identify new way to increase immune response against cancer and infections

Unique 'Golden Hour' study details ultra-early immune response to trauma

Study shows how omega-3 fatty acids can produce same medicinal qualities as marijuana

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