Efficacy News and Research

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Researchers develop near-infrared fluorophores-based PDT to cure cancer with less side effects

A KAIST research team developed near-infrared fluorophores-based photodynamic therapy that reduced the downside of existing PDTs.

16 Jul 2018

Research provides better understanding of mechanisms underlying memory storage

Memories are formed through long-term changes in synaptic efficacy, a process known as synaptic plasticity, and are stored in the brain in specific neuronal ensembles called engram cells, which are activated during corresponding events.

16 Jul 2018

UW-Madison researchers develop new method to track Parkinson's damage in the heart

A new way to examine stress and inflammation in the heart will help Parkinson's researchers test new therapies and explore an unappreciated way the disease puts people at risk of falls and hospitalization.

13 Jul 2018

Four-protein biomarker blood test improves lung cancer risk assessment for smokers

A four-protein biomarker blood test improves lung cancer risk assessment over existing guidelines that rely solely upon smoking history, capturing risk for people who have ever smoked, not only for heavy smokers, an international research team reports in JAMA Oncology.

12 Jul 2018

Internet filtering tools are ineffective in stopping teens from seeing explicit sexual content

The struggle to shape the experiences young people have online is now part of modern parenthood. As children and teenagers spend increasing amounts of time online, a significant share of parents and guardians now use Internet filtering tools (such as parental controls) to protect their children from accessing sexual material online.

12 Jul 2018

Aeras announces publication of Phase 2 results of two TB vaccines

Aeras, a nonprofit organization dedicated to developing vaccines against tuberculosis (TB), today announced the publication of the full results from a Phase 2, randomized, controlled clinical trial of two TB vaccines-- the currently available BCG vaccine and an investigational vaccine, H4:IC31--in the New England Journal of Medicine (NEJM).

12 Jul 2018

Fighting cancer with engineered cancer cells

Researchers at Brigham and Women's Hospital have engineered cancer cells that track and kill cancer cells. The modified cancer cells have demonstrated anti-cancer efficacy in preclinical studies, destroying both primary and metastatic tumours.

12 Jul 2018

Aurinia’s Phase 2 trial evaluates voclosporin ophthalmic solution for treating dry eye syndrome

Aurinia Pharmaceuticals Inc., a clinical stage biopharmaceutical company focused on the global immunology market, today announced the initiation of its Phase 2 trial evaluating voclosporin ophthalmic solution (VOS) for the treatment of dry eye syndrome (DES).

12 Jul 2018

New clinical trial to evaluate virotherapy and immunotherapy combination for ovarian, colorectal cancers

Ludwig Cancer Research and the Cancer Research Institute announce the initiation of a clinical trial to evaluate the combination of ONCOS-102, an experimental anti-tumor virotherapy, with the checkpoint blockade antibody IMFINZI (durvalumab) for advanced ovarian and colorectal cancers.

12 Jul 2018

New 3D model of 1918 H1 pandemic influenza virus could benefit VLP vaccine projects

Virus-like particles are protein-based structures that mimic viruses and bind to antibodies. Because VLPs are not infectious, they show considerable promise as vaccine platforms for many viral diseases, including influenza.

12 Jul 2018

Novel informatics tool helps predict genomic features associated with specific drug responses

The rise of genomics, the shift from considering genes singly to collectively, is adding a new dimension to medical care; biomedical researchers hope to use the information contained in human genomes to make better predictions about individual health, including responses to therapeutic drugs.

12 Jul 2018

Study identifies cost-effective strategy to treat nail fungus using nanotechnology

Onychomycosis, a nail fungus that causes nail disfigurement, pain, and increased risk of soft tissue infection, impacts millions of people worldwide. There are several topical antifungal treatments currently available; however, treatment failure remains high due to a number of factors.

11 Jul 2018

Researchers use genome editing to reduce cholesterol levels in animal model

Using genome editing to inactivate a protein called PCSK9 effectively reduces cholesterol levels in rhesus macaques, a species of monkey, according to researchers from the Perelman School of Medicine at the University of Pennsylvania.

10 Jul 2018

Geography may be destiny in end-of-life care for cancer patients

When it comes to how much end-of-life care a patient with cancer receives, geography may, indeed, be destiny, according to new research led by Harvard Medical School that found striking differences in terminal care across different parts of the country.

10 Jul 2018

'The Pediatric Asthma Yardstick' offers guidance to treat children of all ages

Although about 10 percent of school-aged children in the United States have asthma, there are few comprehensive U.S. guidelines for treating pediatric asthma.

10 Jul 2018

Human trial identifies common blood pressure medication as safe, effective therapy for diabetes

Researchers at the University of Alabama at Birmingham Comprehensive Diabetes Center have discovered a safe and effective novel therapy to reduce insulin requirements and hypoglycemic episodes in adult subjects with recent onset Type 1 diabetes by promoting the patient's own beta cell function and insulin production -- the first such discovery to target diabetes in this manner.

9 Jul 2018

Researchers use gene therapy to cure obesity and type 2 diabetes in mice

A research team from the UAB led by Professor Fatima Bosch has managed to cure obesity and type 2 diabetes in mice using gene therapy.

9 Jul 2018

Preventative HIV vaccines induce robust, comparable immune responses in humans and monkeys

More than three decades after the identification of the human immunodeficiency virus, scientists are still working to develop a preventative vaccine that could finally put an end to the epidemic for which there are nearly two million new infections each year.

9 Jul 2018

Fourth-generation retinoid may have improved efficacy and safety profile to treat acne

Topical retinoids, which target retinoic acid receptors, are commonly used to treat acne. New research published in theBritish Journal of Dermatologyreveals that trifarotene, a fourth-generation retinoid with potent and selective activity against only one particular retinoic acid receptor, may have an improved efficacy and safety profile compared with less selective retinoids.

6 Jul 2018

New small molecules offer promising new way to treat autoinflammatory diseases

EPFL scientists have discovered two small-molecule compound series that can effectively block a central pathway of the innate immune system, offering a promising new way for treating autoinflammatory diseases.

4 Jul 2018

Efficacy News and Research

Researchers develop near-infrared fluorophores-based PDT to cure cancer with less side effects

Research provides better understanding of mechanisms underlying memory storage

UW-Madison researchers develop new method to track Parkinson's damage in the heart

Four-protein biomarker blood test improves lung cancer risk assessment for smokers

Internet filtering tools are ineffective in stopping teens from seeing explicit sexual content

Aeras announces publication of Phase 2 results of two TB vaccines

Fighting cancer with engineered cancer cells

Aurinia’s Phase 2 trial evaluates voclosporin ophthalmic solution for treating dry eye syndrome

New clinical trial to evaluate virotherapy and immunotherapy combination for ovarian, colorectal cancers

New 3D model of 1918 H1 pandemic influenza virus could benefit VLP vaccine projects

Novel informatics tool helps predict genomic features associated with specific drug responses

Study identifies cost-effective strategy to treat nail fungus using nanotechnology

Researchers use genome editing to reduce cholesterol levels in animal model

Geography may be destiny in end-of-life care for cancer patients

'The Pediatric Asthma Yardstick' offers guidance to treat children of all ages

Human trial identifies common blood pressure medication as safe, effective therapy for diabetes

Researchers use gene therapy to cure obesity and type 2 diabetes in mice

Preventative HIV vaccines induce robust, comparable immune responses in humans and monkeys

Fourth-generation retinoid may have improved efficacy and safety profile to treat acne

New small molecules offer promising new way to treat autoinflammatory diseases

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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