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Scientists reveal ‘anti-metastatic surveillance’ role of Caveolin-1 protein

A new study conducted at the VIB-KU Leuven Center for Cancer Biology in Belgium has labeled the protein Caveolin-1 as a high-potential pursuit in the fight against cancer.

5 Dec 2017

Overcoming Challenges of Assays of Complex Cellular Models with Real-Time Live-Cell Analysis

There's a continued drive towards making in vitro assays ever more translational towards in vivo models and ultimately the clinic. This ties in with the resurgence of phenotypic screening and is a response to the perceived poor translation of the traditional simple cell-based assays, often developed to study just single protein targets.

From Sartorius 5 Dec 2017

Clearance of cancer cell debris via pro-resolving mediators can prevent tumor recurrence

Cancer therapies are designed to kill tumor cells, but produce tumor cell debris in the process. In a study published in The Journal of Experimental Medicine, researchers from Brigham and Women's Hospital and colleagues show that leftover debris can stimulate inflammation and tumor growth, but that molecules called resolvins can block that unwanted inflammatory response.

5 Dec 2017

Scientists investigate new role of old protein in breast cancer

Scientists led by Dr Chris Toseland of the University's School of Biosciences studied a protein called Myosin VI, a molecular motor which acts as a courier to transport other proteins within our cells.

4 Dec 2017

New treatment aims to target abnormally shaped protein in deadly childhood brain cancer

Children with an extremely deadly form of brain cancer might benefit from a new treatment that aims to direct an immune response against an abnormally shaped protein found exclusively on cancer cells, according to a new study led by UC San Francisco researchers.

4 Dec 2017

Study reveals gene linked to metastatic melanoma

A study by Craig J. Ceol, PhD, assistant professor of molecular medicine at the University of Massachusetts Medical School, has revealed a protein active during early embryo development called GDF6 plays a primary role in metastatic melanoma.

4 Dec 2017

Innovative technique makes low-grade gliomas visible

Gliomas are a type of brain tumor characterized by a poor prognosis. In order to improve this prognosis, as much of the tumor as possible must be removed safely during the neurosurgical operation.

4 Dec 2017

UC San Diego researchers receive nearly $8 million grant for new stem cell-based AML treatments

The Independent Citizens Oversight Committee of the California Institute for Regenerative Medicine unanimously approved yesterday two grants worth a total of almost $8 million to University of California San Diego School of Medicine researchers investigating novel stem cell-based treatments for acute myeloid leukemia or AML.

4 Dec 2017

Chemotherapy-generated debris from dead and dying cancer cells can stimulate tumor growth

Cancer therapies including radiation and chemotherapy seek to treat the disease by killing tumor cells. Now a team including researchers at Beth Israel Deaconess Medical Center have shown that the dead and dying cancer cells generated by chemotherapy and targeted cancer therapy paradoxically trigger inflammation that promotes aggressive tumor growth.

1 Dec 2017

Researchers identify vulnerability for glioblastoma subtypes

Glioblastoma, the most common and aggressive form of brain cancer, typically fails to respond to treatment or rapidly becomes drug resistant.

1 Dec 2017

Researchers refine method to improve early detection of ovarian cancer

Researchers at Rice University and the University of Texas MD Anderson Cancer Center have refined and, for the first time, run in vivo tests of a method that may allow nanotube-based probes to locate specific tumors in the body.

1 Dec 2017

Anti-aging protein could be used as target for rejuvenating cells in the immune system

Anti-aging proteins have long been shown to protect against age-related diseases, such as cancer, neurodegeneration, and cardiovascular disease. A study by researchers at the Gladstone Institutes now reveals that one such protein could also be targeted to rejuvenate cells in the immune system.

1 Dec 2017

New targeted treatment could benefit patients with certain pancreatic tumors

Researchers at the University of Cincinnati College of Medicine have shown that a new targeted treatment could benefit patients with certain pancreatic tumors by preventing spread of the cancer and protecting their heart from damage--a direct result of the tumor.

1 Dec 2017

Novel drug combination could enhance immunotherapy responses in patients with lung cancer

Johns Hopkins Kimmel Cancer Center researchers and colleagues have identified a novel drug combination therapy that could prime nonsmall cell lung cancers to respond better to immunotherapy.

30 Nov 2017

Papillomaviruses linked to UV light promote development of non-melanoma skin cancer

UV radiation has been known for a long time to be a risk factor for the development of skin cancer. Simultaneous infection with human papillomaviruses (HPV) has also been suspected to promote skin cancer, particularly in organ transplant recipients.

30 Nov 2017

Molecule plays double role in maintaining gut health and promoting diseases

A molecule that controls intestinal cell growth plays a dual role maintaining gut health and promoting diseases such as cancer, says a study in eLife.

30 Nov 2017

New vaccine technique can effectively combat breast cancer, mice study shows

A new vaccine technique can fight a certain type of breast cancer in mice. So-called HER2-positive breast cancer accounts for between 20 and 30 per cent of all cases of breast cancer in humans.

30 Nov 2017

Understanding molecular mechanisms of signaling pathways to inhibit cancer invasion

The German Research Foundation has approved the renewal application for the Collaborative Research Center 850 "Control of Cell Motility in Morphogenesis, Cancer Invasion, and Metastasis".

30 Nov 2017

'Aggressive' surgery for early stage lung cancer provides better outcomes

Patients with early stage lung cancer live longer when they receive a lobectomy- the most common type of operation for the disease- rather than a less extensive operation or radiation treatment, according to a study published online today in The Annals of Thoracic Surgery.

30 Nov 2017

Researchers unlock genetic processes underlying cancer

For many, breast cancer is more than just a disease – it's personal. One in eight women will be diagnosed with breast cancer at some point in their lives. But through new discoveries at the genetic level, the personal nature of cancer will eventually be what helps to beat it.

29 Nov 2017

Tumor News and Research

Scientists reveal ‘anti-metastatic surveillance’ role of Caveolin-1 protein

Overcoming Challenges of Assays of Complex Cellular Models with Real-Time Live-Cell Analysis

Clearance of cancer cell debris via pro-resolving mediators can prevent tumor recurrence

Scientists investigate new role of old protein in breast cancer

New treatment aims to target abnormally shaped protein in deadly childhood brain cancer

Study reveals gene linked to metastatic melanoma

Innovative technique makes low-grade gliomas visible

UC San Diego researchers receive nearly $8 million grant for new stem cell-based AML treatments

Chemotherapy-generated debris from dead and dying cancer cells can stimulate tumor growth

Researchers identify vulnerability for glioblastoma subtypes

Researchers refine method to improve early detection of ovarian cancer

Anti-aging protein could be used as target for rejuvenating cells in the immune system

New targeted treatment could benefit patients with certain pancreatic tumors

Novel drug combination could enhance immunotherapy responses in patients with lung cancer

Papillomaviruses linked to UV light promote development of non-melanoma skin cancer

Molecule plays double role in maintaining gut health and promoting diseases

New vaccine technique can effectively combat breast cancer, mice study shows

Understanding molecular mechanisms of signaling pathways to inhibit cancer invasion

'Aggressive' surgery for early stage lung cancer provides better outcomes

Researchers unlock genetic processes underlying cancer

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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