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Experimental vaccine shows significant promise in preventing rheumatoid arthritis

Researchers at The University of Toledo have developed an experimental vaccine that shows significant promise in preventing rheumatoid arthritis, a painful autoimmune disease that cannot currently be cured.

4 Oct 2021

Key lessons from COVID-19 pandemic for scientific and clinical communities

In a paper published in the journal Cell, researchers have investigated and criticized clinical care management and drug administration within the pandemic.

4 Oct 2021

Persistent leukocyte changes three months after mild SARS-CoV-2 infection

A recent study discusses the rate of changes in peripheral blood white cells in individuals who have recovered from SARS-CoV-2 infection.

3 Oct 2021

Scientists describe SARS-CoV-2 uptake in tissue-resident human macrophages enhanced by virus-specific antibodies

Now, in a new news study posted to the bioRxiv* preprint server, researchers have successfully induced similar chronicity associated with SARS-CoV-2 infection in MISTRG6-hACE2 humanized mice.

29 Sep 2021

Effect of biologic therapy on COVID-19 in children suffering from rheumatic diseases

A new study aimed to determine the course of SARS-CoV-2 infection in children suffering from rheumatic disease and were receiving bDMARD treatment.

29 Sep 2021

SARS-CoV-2 viroporin activity impacts viral infectivity and pathogenicity

A team of researchers studied the two main viroporins of SARS-CoV-2, namely Orf3a and Envelope (E) protein, from a structural viewpoint.

29 Sep 2021

Vaccine-induced SARS-CoV2 immune responses decline at similar rates as those after infection, study finds

A new preprint describes the causal role of waning antibody titers in decreased antibody persistence at one year.

29 Sep 2021

Review of COVID-19 clinical and viral characteristics, pathogenesis, and genetics

A new review article investigates the clinical and viral characteristics, pathogenesis, as well as human genetic basis associated with COVID-19.

27 Sep 2021

WHO experts recommend antibody treatment for two specific groups of patients with covid-19

A treatment combining two antibodies (casirivimab and imdevimab) is recommended for two specific groups of patients with covid-19 by a WHO Guideline Development Group (GDG) panel of international experts and patients in The BMJ today.

24 Sep 2021

The impact of multiple sclerosis therapy on COVID-19 vaccine efficacy

In a paper, the vaccine-induced cellular and immune response of MS patients receiving a range of therapies are assessed.

23 Sep 2021

Study findings could lead to novel ways to overcome tumor resistance to immunotherapies

Cancer-fighting immune cells in patients with lung cancer whose tumors do not respond to immunotherapies appear to be running on a different "program" that makes them less effective than immune cells in patients whose cancers respond to these immune treatments, suggests a new study led by researchers at the Johns Hopkins Kimmel Cancer Center Bloomberg~Kimmel Institute for Cancer Immunotherapy.

22 Sep 2021

Changes in fibrin clot structure contributes to thrombosis risk in severe COVID-19

Researchers from Europe recently demonstrated altered levels of factor XII (FXII) and its activation products in 2 independent cohorts of critically ill patients with COVID-19 compared to patients suffering from severe acute respiratory distress syndrome caused by the influenza virus (acute respiratory distress syndrome (ARDS)-influenza).

21 Sep 2021

Research could lead to new treatment option for breast cancer patients with brain metastases

Breast cancer patients whose cancer spreads to the brain may soon have new treatment options, thanks to research led by CU Cancer Center member Diana Cittelly, PhD.

21 Sep 2021

T cell immunity induced after mild COVID could contribute to protection against re-infection

An interesting new study finds that in both adults and children, a mild infection with the SARS-CoV-2 elicits an antigen-specific memory T-cell response.

20 Sep 2021

Research on SARS-CoV-2 and dendritic cells may explain why virus is so virulent

In a recent study released on the bioRxiv* preprint server, the researchers suggest that an aberrant inflammatory reaction associated with COVID-19 could be a result of escape from direct sensing by toll-like receptors (TLRs). Moreover, the researchers indicate that this phenomenon might underlie the lack of efficient immunity to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) early during infection.

20 Sep 2021

Pfizer vaccine induces strong immunity in elderly with prior COVID-19

A new study discusses the vaccination response in elderly who were vaccinated with one dose of the Pfizer vaccine 15 months after contracting COVID-19.

16 Sep 2021

Research reveals vital role of protein-coding gene in tumor development and immune therapy response

Researchers from the Case Comprehensive Cancer Center uncovered the potentially important role of the protein-coding gene, MYO10, in tumor development and immune therapy response. Their findings were published today in Science Advances.

16 Sep 2021

Flavonoids can potentially help prevent COVID-19-induced diarrhea, study finds

A recent study published in Tropical Biomedicine determines whether flavonoids can help prevent diarrhea caused by SARS-CoV-2 infection.

15 Sep 2021

Phase I trial investigates using antiparasitic nitazoxanide for treatment of COVID-19

In a recent study, researchers investigate the possibility of using the thiazolide antiparasitic nitazoxanide for the treatment of COVID-19.

15 Sep 2021

Deep profiling of SARS-CoV-2 immune response amongst the mildly symptomatic

In a research paper recently uploaded to the medRxiv* preprint server by Capelle et al. (September 2nd, 2021), the immune response of mild and hospitalized COVID-19 patients is compared, finding that early T-cell response is a vital indicator of SARS-CoV-2 disease severity.

15 Sep 2021

Interleukin 2 News and Research

Experimental vaccine shows significant promise in preventing rheumatoid arthritis

Key lessons from COVID-19 pandemic for scientific and clinical communities

Persistent leukocyte changes three months after mild SARS-CoV-2 infection

Scientists describe SARS-CoV-2 uptake in tissue-resident human macrophages enhanced by virus-specific antibodies

Effect of biologic therapy on COVID-19 in children suffering from rheumatic diseases

SARS-CoV-2 viroporin activity impacts viral infectivity and pathogenicity

Vaccine-induced SARS-CoV2 immune responses decline at similar rates as those after infection, study finds

Review of COVID-19 clinical and viral characteristics, pathogenesis, and genetics

WHO experts recommend antibody treatment for two specific groups of patients with covid-19

The impact of multiple sclerosis therapy on COVID-19 vaccine efficacy

Study findings could lead to novel ways to overcome tumor resistance to immunotherapies

Changes in fibrin clot structure contributes to thrombosis risk in severe COVID-19

Research could lead to new treatment option for breast cancer patients with brain metastases

T cell immunity induced after mild COVID could contribute to protection against re-infection

Research on SARS-CoV-2 and dendritic cells may explain why virus is so virulent

Pfizer vaccine induces strong immunity in elderly with prior COVID-19

Research reveals vital role of protein-coding gene in tumor development and immune therapy response

Flavonoids can potentially help prevent COVID-19-induced diarrhea, study finds

Phase I trial investigates using antiparasitic nitazoxanide for treatment of COVID-19

Deep profiling of SARS-CoV-2 immune response amongst the mildly symptomatic

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