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Scientists uncover hidden genetic causes of congenital heart disease

Scientists at the Icahn School of Medicine at Mount Sinai and collaborators have identified novel genetic interactions that may contribute to congenital heart disease (CHD), a common birth defect.

20 Feb 2025

New discovery offers hope in the battle against pulmonary fibrosis

A discovery at Duke-NUS Medical School offers new hope in the battle against pulmonary fibrosis, a debilitating lung condition that progressively makes it harder for patients to breathe.

20 Feb 2025

Mice study offers insight into how the brain balances risk and reward

Every day, our brain makes thousands of decisions, big and small. Any of these decisions - from the least consequential such as picking a restaurant to the more important such as pursuing a different career or moving to a new city - may result in better or worse outcomes.

19 Feb 2025

Genetic mutation linked to schizophrenia in both humans and mice

A genetic mutation found in two human patients with schizophrenia also increased schizophrenia-related behaviors in mice with the same mutation, a rare finding of a direct genetic link to psychosis, report researchers at the University of Illinois Urbana-Champaign and colleagues in Massachusetts and Germany.

19 Feb 2025

Infant exposure to herpes virus may cause memory problems later in life

Very early exposure to even a very small dose of herpes simplex virus (HSV) in infant mice can lead to cognitive decline later in life, according to findings from a new Dartmouth-led study, in collaboration with Harvard Medical School and published in the journal PLoS Pathogens.

19 Feb 2025

Older adults and women more likely to develop postoperative infections after heart surgery

One in five older adults gets an infection up to six months after heart surgery - with women far more likely to develop one, according to studies led by Michigan Medicine.

19 Feb 2025

UTHealth Houston launches at-home telerehabilitation trial for stroke patients in Rio Grande Valley

A new at-home telerehabilitation care service for stroke patients will be offered to residents of Cameron County in the Rio Grande Valley as part of a randomized clinical trial led by researchers from across UTHealth Houston.

18 Feb 2025

Study shows life expectancy stagnation in Europe

The rise in human life expectancy has slowed down across Europe since 2011, according to research from the University of East Anglia and partners.

18 Feb 2025

Internal body clock influences eating habits of obese teens

Researchers found that teens with obesity ate more later in the day than their peers of healthy weight, and that their eating behaviors were strongly influenced by their internal body clock.

17 Feb 2025

MHIN Asia Hub unveiled to address mental health challenges in Asia

In a significant advancement for mental health care, the SingHealth Duke-NUS Global Health Institute, in collaboration with the Mental Health Innovation Network (MHIN), unveiled today the MHIN Asia Hub.

17 Feb 2025

AI tool speeds up patient screening for heart failure trials

Artificial intelligence (AI) can rapidly screen patients for clinical trial enrollment, according to a new study published in JAMA and led by Mass General Brigham researchers.

17 Feb 2025

Groundbreaking ALS platform trial accelerates research and drug testing

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with few treatment options. Since 2018, the Sean M. Healey & AMG Center for ALS at Massachusetts General Hospital (MGH), a founding member of the Mass General Brigham healthcare system, has been working with national and international stakeholders to accelerate ALS research by launching the first platform trial in ALS to simultaneously test multiple drugs using shared trial infrastructure and placebo data.

17 Feb 2025

Gene therapy shows promise in treating SCN1B-linked epileptic encephalopathies

Dravet syndrome and other developmental epileptic encephalopathies are rare but devastating conditions that cause a host of symptoms in children, including seizures, intellectual disability, and even sudden death.

14 Feb 2025

Sotagliflozin could be used to reduce the risk of deadly cardiovascular events, trial shows

Sotagliflozin, a drug recently approved by the Food and Drug Administration to treat type 2 diabetes and kidney disease with additional cardiovascular risk factors, can significantly reduce heart attack and stroke among these patients, according to results from an international clinical trial led by a Mount Sinai researcher.

14 Feb 2025