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Girls more likely to develop metabolic alterations associated with obesity than boys

A study of 92 adolescents conducted in Brazil suggests girls are more likely than boys to develop metabolic alterations associated with obesity, such as high blood pressure and excessive blood levels of cholesterol and triglycerides (dyslipidemia).

12 May 2021

New method to efficiently deliver drugs into cells

A new, patented method called Progressive Mechanoporation makes it possible to mechanically disrupt the membranes of cells for a short time period and let drugs or genes inside cells.

12 May 2021

Measuring metabolic 'fluxes' could help scientists advance new tuberculosis drugs

Mycobacterium tuberculosis is incredible in that it can survive for decades within its human host. It does this by varying its diet to successfully steal nutrients from the human host including immune cells; it is known to acquire and absorb multiple carbon sources from the body during infection.

12 May 2021

New drug-like compound could effectively block a critical step in malaria parasite life cycle

Researchers at the Francis Crick Institute and the Latvian Institute of Organic Synthesis have designed a drug-like compound which effectively blocks a critical step in the malaria parasite life cycle and are working to develop this compound into a potential first of its kind malaria treatment.

12 May 2021

A new method for efficient and automated production of synthetic DNA

Chemically synthesized short DNA sequences are extremely important ingredients with countless uses in research laboratories, hospitals, and in industry, like in the method for identifying COVID-19.

12 May 2021

Researchers develop a hairpin-shaped bicyclic peptide to fight cancer

The inhibition of pathological protein-protein interactions is a promising approach for treating a large number of diseases, including many forms of cancer.

12 May 2021

Case study examines prescriptions and healthcare use in non-hospitalized COVID-19 recoverers

In a new study published in The Lancet, a team of researchers examined prescription drug and healthcare use after SARS-CoV-2 infection in those who did not require hospital admission.

12 May 2021

Don’t eat the yellowstone snow: Elite ski resort aims to turn sewage into powder

An exclusive Montana resort wants to turn sewage into snow so that its rich and famous members can ski its slopes in a winter season that's shrinking because of climate change.

12 May 2021

HIV patients are more likely to die from COVID-19 infection

Over the past year, studies have revealed that certain pre-existing conditions, such as cancer, diabetes and high blood pressure, can increase a person's risk of dying from COVID-19.

12 May 2021

New clinical trial to test possible therapeutics for COVID-19 in hospitalized patients

The Clinical Trials Network of Tennessee (CTN2) at the University of Tennessee Health Science Center has contracted a new clinical trial to test possible therapeutics for COVID-19 in hospitalized patients. This new trial brings the total generated by CTN2 contracts for the university to nearly $7 million.

12 May 2021

Fungal disease is emerging among hundreds of COVID-19 patients in India, shows study

Authorities scramble to provide drugs to treat a fungal disease affecting India's COVID-19 patients. A fungal disease called mucormycosis is emerging among hundreds of COVID-19 patients in India, placing further strain on hospitals already at breaking point.

12 May 2021

Low dose of a four-drug combination helps prevent cancer metastasis in mice

Low doses of a four-drug combination helps prevent the spread of cancer in mice without triggering drug resistance or recurrence, shows a study published today in eLife.

11 May 2021

Spiritual fitness and meditative practice may reduce multiple risk factors for Alzheimer's disease

It is projected that up to 152 million people worldwide will be living with Alzheimer's disease (AD) by 2050. To date there are no drugs that have a substantial positive impact on either the prevention or reversal of cognitive decline.

11 May 2021

Researchers design compounds that prevent SARS-CoV-2 entry in human lung cells

Researchers have designed a new class of TMPRSS2 inhibitors that have shown broad antiviral activity against coronaviruses, including the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

11 May 2021

Combining two medications doubles gout treatment success, study reveals

By combining two medications, researchers at Michigan Medicine optimized a therapy for people with gout, a condition that causes severe damage and disability if left untreated.

11 May 2021

Researchers discover the second possible effective mechanism of remdesivir

The virostatic agent remdesivir was developed to disrupt an important step in the propagation of RNA viruses, to which SARS-CoV-2 also belongs: the reproduction of the virus's own genetic material. This is present as RNA matrices with which the host cell directly produces virus proteins.

11 May 2021

Severe COVID-19 linked to genetic clotting predisposition

Thus, the need to stratify the risk of severe or critical disease in patients presenting with SARS-CoV-2 infection remains a crying necessity. A new preprint research paper posted to the medRxiv server discusses the relationship between severe disease and pre-existing susceptibility to clots and other diseases of the cardiovascular system.

11 May 2021

GeroSense AI tracks biological age and resilience via smartphone sensor data

Gero has developed and validated GeroSense AI to track biological age and resilience via smartphone sensor data. The performance of the new health and aging markers have been recently reported in a paper in Aging US.

11 May 2021

New approach targeting viral RNA could lead to broad spectrum anti-viral drugs

A new approach to tackling viruses by targeting the 'control center' in viral RNA could lead to broad spectrum anti-viral drugs and provide a first line of defense against future pandemics, according to new research at the University of Birmingham.

11 May 2021

FDA expands emergency use authorization for Pfizer-BioNTech COVID-19 Vaccine

Today, the U.S. Food and Drug Administration expanded the emergency use authorization (EUA) for the Pfizer-BioNTech COVID-19 Vaccine for the prevention of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to include adolescents 12 through 15 years of age.

10 May 2021

Drugs News and Research

Girls more likely to develop metabolic alterations associated with obesity than boys

New method to efficiently deliver drugs into cells

Measuring metabolic 'fluxes' could help scientists advance new tuberculosis drugs

New drug-like compound could effectively block a critical step in malaria parasite life cycle

A new method for efficient and automated production of synthetic DNA

Researchers develop a hairpin-shaped bicyclic peptide to fight cancer

Case study examines prescriptions and healthcare use in non-hospitalized COVID-19 recoverers

Don’t eat the yellowstone snow: Elite ski resort aims to turn sewage into powder

HIV patients are more likely to die from COVID-19 infection

New clinical trial to test possible therapeutics for COVID-19 in hospitalized patients

Fungal disease is emerging among hundreds of COVID-19 patients in India, shows study

Low dose of a four-drug combination helps prevent cancer metastasis in mice

Spiritual fitness and meditative practice may reduce multiple risk factors for Alzheimer's disease

Researchers design compounds that prevent SARS-CoV-2 entry in human lung cells

Combining two medications doubles gout treatment success, study reveals

Researchers discover the second possible effective mechanism of remdesivir

Severe COVID-19 linked to genetic clotting predisposition

GeroSense AI tracks biological age and resilience via smartphone sensor data

New approach targeting viral RNA could lead to broad spectrum anti-viral drugs

FDA expands emergency use authorization for Pfizer-BioNTech COVID-19 Vaccine

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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