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Common oral antibiotics tied to increased risk of severe drug-induced rashes

Two classes of commonly prescribed oral antibiotics are associated with the greatest risk for severe drug rashes that can lead to emergency department visits, hospitalizations and even death, according to a new study.

8 Aug 2024

Insilico Medicine's pan-TEAD inhibitor ISM6331 receives FDA IND clearance for mesothelioma treatment

Insilico Medicine ("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven biotechnology company, today announced ISM6331, potential best-in-class pan-TEAD inhibitor, has received the U.S. Food and Drug Administration (FDA) Investigational New Drug (IND) clearance for the treatment of mesothelioma, following the grant of Orphan Drug Designation (ODD) in June 2024. It brings the total number of IND-approved molecules of Insilico to nine.

8 Aug 2024

Alcohol use in older adults linked to increased risk of severe head trauma after falls

Nationally, falls remain the leading cause of both fatal and non-fatal injuries in older adults and are the leading cause of traumatic brain injury.

8 Aug 2024

Drug shows new promise in treating breast cancer with brain metastases or recurrent glioblastoma

A drug effective in treating breast cancer shows new promise in addressing breast cancer with brain metastases or recurrent glioblastoma, as reported by results of a prospective window-of-opportunity trial at the University of Texas Health Science Center at San Antonio (UT Health San Antonio).

8 Aug 2024

KFF Health News' 'What the Health?': The Walz record

Minnesota Gov. Tim Walz is Vice President Kamala Harris' choice of running mate. Walz — also a former U.S. congressman, high school teacher, and member of the National Guard — has a folksy, Midwestern affect and a liberal record.

8 Aug 2024

Low-acid diets with fruits and vegetables significantly improve kidney and heart health in hypertension patients

Study found that low-acid diets, particularly those rich in fruits and vegetables, offer significant kidney and cardiovascular protection in patients with primary hypertension, outperforming traditional medical care.

8 Aug 2024

C-Path supports innovative ALS, neurodegenerative disease research with new grant

Critical Path Institute's (C-Path) Translational Therapeutics Accelerator (TRxA) announced today a new research grant awarded to Daniela C. Zarnescu, Ph.D., Professor of Cellular and Molecular Physiology at Penn State University College of Medicine, in collaboration with Jon Njardarson, Ph.D., Professor at the University of Arizona.

8 Aug 2024

Breakthrough discovery could boost stem-cell transplants by improving cell mobilization

A discovery by a three-member Albert Einstein College of Medicine research team may boost the effectiveness of stem-cell transplants, commonly used for patients with cancer, blood disorders, or autoimmune diseases caused by defective stem cells, which produce all the body's different blood cells.

8 Aug 2024

Cannabis dependence associated with increased occurrence of head and neck cancer

A study from the USC Head and Neck Center, part of Keck Medicine of USC and the USC Caruso Department of Otolaryngology – Head and Neck Surgery, suggests that cannabis, the most commonly used illicit substance worldwide, is associated with an increased occurrence of head and neck cancer.

8 Aug 2024

Gene activity can predict severe side effects from melanoma treatment

An activity pattern in certain genes responsible for building proteins known as spleen tyrosine kinases can predict which melanoma patients are likely to have severe side effects from immunotherapy designed to treat the most deadly skin cancer, a new study shows.

8 Aug 2024

Many children with recurrent wheezing have "silent" lung infections, research reveals

Nearly a quarter of children with recurrent wheezing have "silent" lung infections that would be better treated with antiviral medications than commonly prescribed steroids that can carry lifelong side effects, new research from the University of Virginia School of Medicine reveals.

8 Aug 2024

Innovative program promotes positive adolescent romantic relationships and use of effective contraceptives

Romantic relationships play an important part in adolescent development. Most young people have had at least one romantic relationship by middle adolescence (ages 14 to17).

8 Aug 2024

New insights into the role of cancer-associated fibroblasts in promoting lymphatic metastasis

Lymph node metastasis is a crucial factor in cancer progression, significantly affecting patient prognosis and treatment outcomes.

8 Aug 2024

Individualized neoantigen cancer therapy demonstrates safety and efficacy in early trials

For decades, researchers have worked to develop therapies that can prime the immune system to recognize and attack proteins on the surface of tumor cells.

8 Aug 2024

Alcohol use disorders in parents linked to accelerated aging in children

Researchers at the Texas A&M School of Veterinary Medicine and Biomedical Sciences (VMBS) have discovered that parents who struggle with alcohol use disorders can pass along symptoms of early aging to their children, affecting them well into adulthood.

8 Aug 2024

Polycystic ovary syndrome linked to greater risk of disordered eating in women

Women with the common reproductive and metabolic condition polycystic ovary syndrome (PCOS) face a greater risk of developing bulimia, binge eating disorder and disordered eating, according to new research published in The Journal of Clinical Endocrinology & Metabolism.

8 Aug 2024

Consuming foods with erythritol increases risk of cardiovascular events, study shows

New Cleveland Clinic research shows that consuming foods with erythritol, a popular artificial sweetener, increases risk of cardiovascular events such as heart attack and stroke.

8 Aug 2024

New $11.3 million grant to explore endothelial cell dysfunction in cardiovascular disease

With a new $11.3 million Program Project grant from the National Institutes of Health, experts from the Vascular Biology Center at the Medical College of Georgia at Augusta University are working to better understand the underlying mechanisms of cardiovascular disease.

8 Aug 2024

Review reveals high rates of opioid dependence among chronic pain patients

A new scientific review of 148 studies enrolling over 4.3 million adult chronic pain patients treated with prescription opioid painkillers has found that nearly one in ten patients experiences opioid dependence or opioid use disorder and nearly one in three shows symptoms of dependence and opioid use disorder.

8 Aug 2024

The politics holding back Medicaid expansion in some Southern states

For Roderick Givens, a radiation oncologist, the expansion of Medicaid isn't just a policy issue. He practices medicine in a rural area in the Mississippi Delta and he sees daily how Medicaid coverage could help his uninsured patients.

8 Aug 2024

Medicine News and Research

Common oral antibiotics tied to increased risk of severe drug-induced rashes

Insilico Medicine's pan-TEAD inhibitor ISM6331 receives FDA IND clearance for mesothelioma treatment

Alcohol use in older adults linked to increased risk of severe head trauma after falls

Drug shows new promise in treating breast cancer with brain metastases or recurrent glioblastoma

KFF Health News' 'What the Health?': The Walz record

Low-acid diets with fruits and vegetables significantly improve kidney and heart health in hypertension patients

C-Path supports innovative ALS, neurodegenerative disease research with new grant

Breakthrough discovery could boost stem-cell transplants by improving cell mobilization

Cannabis dependence associated with increased occurrence of head and neck cancer

Gene activity can predict severe side effects from melanoma treatment

Many children with recurrent wheezing have "silent" lung infections, research reveals

Innovative program promotes positive adolescent romantic relationships and use of effective contraceptives

New insights into the role of cancer-associated fibroblasts in promoting lymphatic metastasis

Individualized neoantigen cancer therapy demonstrates safety and efficacy in early trials

Alcohol use disorders in parents linked to accelerated aging in children

Polycystic ovary syndrome linked to greater risk of disordered eating in women

Consuming foods with erythritol increases risk of cardiovascular events, study shows

New $11.3 million grant to explore endothelial cell dysfunction in cardiovascular disease

Review reveals high rates of opioid dependence among chronic pain patients

The politics holding back Medicaid expansion in some Southern states

Everything there is to know about biosimilars eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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