Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

Researchers propose DLPE method to extract interpretable and predictive subvisual features from CT scans of COVID-19 inpatients and survivors

Researchers assessed deep learning workflows involved in CT scans of COVID-19.

25 May 2022

Largest study to date on long COVID identifies a broad list of diagnoses

Researchers characterize post-acute sequelae of SARS-CoV-2 infection.

25 May 2022

Hydration restores airway integrity in people with cystic fibrosis

Cystic fibrosis is a rare genetic disease which can cause very serious symptoms. In particular, patients suffer from chronic bacterial infections that can lead to respiratory failure.

24 May 2022

Insilico Medicine nominates novel preclinical candidate targeting 3CL protease for COVID-19 treatment

Insilico Medicine, a clinical-stage end-to-end artificial intelligence (AI)-driven drug discovery company, today announced its nomination of a novel preclinical candidate (PCC) targeting 3C-like (3CL) protease for the treatment of COVID-19.

24 May 2022

UH experts in cloning and stem cell science take the first step toward unraveling cystic fibrosis

Two nationally recognized experts in cloning and stem cell science from the University of Houston are taking the first step toward limiting the consequences of chronic inflammation in cystic fibrosis (CF) by identifying the source of this persistent and enigmatic inflammation in CF lungs.

24 May 2022

Investigation of long-COVID in children with immunodeficiency

A new study focused on evaluating the prevalence of characteristic symptoms of Long COVID in immunodeficient and immunocompetent children.

23 May 2022

The enigma of post-acute infection syndromes

In a recent review published in the journal Nature Medicine, researchers summarized known literature findings of the unexplained post-acute infection syndromes (PAISs).

20 May 2022

Patients with COVID-19 pneumonitis and moderate to severe ARDS treated with sildenafil

A new study published in the British Journal of Anaesthesia aimed to determine whether sildenafil could improve gaseous exchange in patients with COVID-19 ARDS with pulmonary hypertension, RV dysfunction, or both.

17 May 2022

Researchers use bacteriophages to treat antibiotic-resistant mycobacterial lung infection

For the first time, researchers have successfully used bacteriophages – viruses that kill bacteria – to treat an antibiotic-resistant mycobacterial lung infection, clearing the way for a young National Jewish Health patient with cystic fibrosis to receive a life-saving lung transplant.

13 May 2022

Direct infection and replication of influenza virus in cardiomyocytes is a primary determinant of cardiac pathology associated with severe influenza

Researchers generated a recombinant influenza virus expressing micro ribonucleic acid (miRNAs) expressed in cardiomyocytes to infect mice, which served as a model to study the etiology of influenza-associated cardiac pathology.

13 May 2022

Direct influenza infection of the heart drives cardiac complications, study reveals

Researchers have shown for the first time in mice that heart problems associated with the flu are not caused by raging inflammation in the lungs, as has long been predicted.

11 May 2022

LJI researchers uncover new drug target for severe asthma, lung fibrosis

If you've ever struggled to breathe, you've had a moment of hypoxia - a lack of oxygen. Hypoxia can have long-term effects. In fact, doctors describe hypoxia as an "initial insult."

9 May 2022

Scientists identify the role of phospholipid in maintaining epithelial cellular adhesion

Cells have certain proteins that help them adhere to each other while covering body surfaces and organs. Loss of these identifying proteins could result in cellular progression towards cancer and, subsequently, metastasis.

9 May 2022

Stem cell therapy prevents type 1 diabetes induced by anti-cancer drugs

Immune checkpoint inhibitors are widely used to treat a variety of cancers; however, one serious side effect is the onset of type 1 diabetes.

6 May 2022

$6 million grant to fund research investigating the role of immune system in heart failure

A new grant for researchers at Washington University School of Medicine in St. Louis will fund research investigating the role of the immune system in heart failure. Finding ways to harness beneficial immune cells could lead to new therapies that encourage the heart to heal after injuries.

2 May 2022

Trial shows the efficacy of anti-TNF drug for patients with early-stage Dupuytren's disease

Researchers at the Kennedy Institute, University of Oxford, led by Professor Jagdeep Nanchahal have demonstrated the efficacy of the anti-TNF drug adalimumab for patients with early-stage Dupuytren's disease.

30 Apr 2022

Researchers use mouse model to explore correlation of impaired interferon-mediated immune response with severe COVID-19

Researchers developed a highly pathogenic mouse-adapted SARS-CoV-2 strain to model mild, moderate, or COVID-19.

26 Apr 2022

CN Bio introduces PhysioMimix NASH ‘in-a-box’ reagent kit

First product within new ‘in-a-box’ range, which harnesses next-generation, human-relevant Liver-on-a-Chip technology to improve the accuracy and efficiency of NASH drug discovery.

From CN Bio 26 Apr 2022

Researchers identify cytokines that can help predict negative outcomes in COVID-19 patients

New research being presented at this year's European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) in Lisbon, Portugal (23-26 April) has identified a panel of cytokines that can help predict which COVID-19 patients are at risk of serious illness and death.

23 Apr 2022

Researchers develop a live imaging system to observe collagen synthesis

"Proteins are the building blocks of our body": You have probably heard this phrase before. Proteins are essential to the formation of our body's structures, and their functioning.

21 Apr 2022

Fibrosis News and Research

Further Reading

Researchers propose DLPE method to extract interpretable and predictive subvisual features from CT scans of COVID-19 inpatients and survivors

Largest study to date on long COVID identifies a broad list of diagnoses

Hydration restores airway integrity in people with cystic fibrosis

Insilico Medicine nominates novel preclinical candidate targeting 3CL protease for COVID-19 treatment

UH experts in cloning and stem cell science take the first step toward unraveling cystic fibrosis

Investigation of long-COVID in children with immunodeficiency

The enigma of post-acute infection syndromes

Patients with COVID-19 pneumonitis and moderate to severe ARDS treated with sildenafil

Researchers use bacteriophages to treat antibiotic-resistant mycobacterial lung infection

Direct infection and replication of influenza virus in cardiomyocytes is a primary determinant of cardiac pathology associated with severe influenza

Direct influenza infection of the heart drives cardiac complications, study reveals

LJI researchers uncover new drug target for severe asthma, lung fibrosis

Scientists identify the role of phospholipid in maintaining epithelial cellular adhesion

Stem cell therapy prevents type 1 diabetes induced by anti-cancer drugs

$6 million grant to fund research investigating the role of immune system in heart failure

Trial shows the efficacy of anti-TNF drug for patients with early-stage Dupuytren's disease

Researchers use mouse model to explore correlation of impaired interferon-mediated immune response with severe COVID-19

CN Bio introduces PhysioMimix NASH ‘in-a-box’ reagent kit

Researchers identify cytokines that can help predict negative outcomes in COVID-19 patients

Researchers develop a live imaging system to observe collagen synthesis

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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