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Dapagliflozin plus calorie restriction boosts remission rates in adults with type 2 diabetes and obesity

Findings indicate that dapagliflozin and calorie restriction together improve weight loss and metabolic health, increasing the likelihood of diabetes remission.

24 Jan 2025

New AI software could speed up drug development

The discovery and development of drugs in pharmacological research – including the risk assessment of active substances in the early phase of drug development – still largely relies on animal experiments.

23 Jan 2025

Study reveals abelacimab’s potential to improve anticoagulation safety for AFib patients

Abelacimab, a factor XI inhibitor, demonstrated a 62–69% reduction in major bleeding compared to rivaroxaban in atrial fibrillation patients at moderate-to-high stroke risk, with comparable safety and efficacy. While ischemic stroke rates were slightly higher, they were not statistically significant, warranting further phase 3 trials for confirmation.

23 Jan 2025

Researchers map genetic differences across children with Wilms tumor

Genetically tailored treatment plans for children with a type of kidney cancer could help provide the most effective care while minimizing side effects as much as possible.

23 Jan 2025

Higher dietary fatty acid intake linked to increased kidney stone risk

Research reveals links between dietary fatty acids and kidney stone risk, highlighting the need for targeted dietary strategies to mitigate this health issue.

22 Jan 2025

Muscle fat infiltration predicts heart disease risk better than BMI, study finds

Skeletal muscle fat infiltration (IMAT) is linked to coronary microvascular dysfunction and increased cardiovascular risk, independent of BMI and traditional risk factors.

21 Jan 2025

Electroacupuncture may aid in personalized ribavirin dosing for long COVID

Various devices are used to study the unique electrical properties of acupuncture points (APs), with Voll's electropuncture diagnostics (EAV) occupying a prominent role.

21 Jan 2025

Study finds potential target for stopping immune system attacks in autoimmune diseases

Houston Methodist researchers have identified a key protein as a potential therapeutic target for stopping the body's immune system from mistakenly attacking itself, offering new hope for treating autoimmune diseases and allergies.

21 Jan 2025

Benefits and risks of popular weight-loss drugs revealed

Demand for weight-loss medications sold under brand names such as Ozempic and Wegovy continues to surge, with a recent study reporting one in eight Americans has taken or is currently using the drugs to treat diabetes, heart disease or obesity.

20 Jan 2025

Researchers create an atlas of health associations for GLP-1 receptor agonists

Insights from a study on GLP-1 receptor agonists reveal benefits for cardiometabolic health, with notable risks for gastrointestinal and musculoskeletal issues.

20 Jan 2025

Androgen clock reveals how hormones shape aging and health

Scientists unveil the androgen clock, a precise epigenetic tool to measure long-term androgen exposure and its role in aging and health.

16 Jan 2025

Protamine sulfate reduces postoperative compression time after dTRA coronary angiography

Announcing a new article publication for Cardiovascular Innovations and Applications journal. With distal transradial access (dTRA), the postoperative compression time remains significantly longer than the recommended range via in practice.

16 Jan 2025

AstraZeneca's Pioneering Research in Heart Failure and ATTR-CM

Mina Makar highlights AstraZeneca's commitment to advancing heart failure research and innovative therapies, addressing critical needs in cardiovascular health.

16 Jan 2025

Unveiling the genetic roots of bicuspid aortic valve

Large and rare duplications and deletions in a chromosome region known as 22q11.2 , which involves genes that regulate cardiac development, are linked to nonsyndromic bicuspid aortic valve disease, according to a new study led by UTHealth Houston researchers.

16 Jan 2025

CGM data offers superior insights into diabetes complications

Data from continuous glucose monitors can predict nerve, eye and kidney damage caused by type 1 diabetes, University of Virginia Center for Diabetes Technology researchers have found. That suggests doctors may be able to use data from the devices to help save patients from blindness, diabetic neuropathy and other life-changing diabetes complications.

16 Jan 2025

Study identifies molecular mechanisms behind gestational diabetes progression

Among those who have had gestational diabetes, about 35% will develop type 2 diabetes within a decade.

15 Jan 2025

Study reveals how bile acids impact immunotherapy in liver cancer

Immunotherapy is a modern approach to cancer treatment that uses a patient's own immune system to help fight tumors.

15 Jan 2025

Racism in obstetric care linked to higher blood pressure in mothers

Mothers of color who faced racism or microaggressions during obstetric care had higher blood pressure after delivering their babies compared to people of color who did not report racism during their care, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

15 Jan 2025

Gut microbes revealed as hidden drivers of aging and cellular decline

Gut microbiota-derived phenylacetylglutamine accelerates aging by driving cellular senescence through mitochondrial dysfunction and DNA damage, offering insights into therapeutic interventions for age-related decline.

14 Jan 2025