Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

NIH grant supports research on cognitive decline in individuals with Lewy body diseases

Penn Medicine researchers will advance their understanding of the underlying causes of cognitive decline in individuals with Lewy body diseases, like Parkinson's, and identify biomarkers that predict which individuals are more likely to develop dementia with a $18 million grant from the National Institutes of Health/National Institute on Aging.

30 Sep 2024

New insights into astrocytes offer hope for Alzheimer's treatment

A research team led by Dr. Hoon Ryu from the Korea Institute of Science and Technology (KIST, President Sang-Rok Oh) Brain Disease Research Group, in collaboration with Director Justin C. Lee of the Institute for Basic Science (IBS, President Do-Young Noh) and Professor Junghee Lee from Boston University Chobanian & Avedisian School of Medicine, has uncovered a new mechanism involving astrocytes for treating Alzheimer's disease (AD) and proposed a novel therapeutic target.

30 Sep 2024

Regulating iron overload: Liraglutide's potential benefits

Researchers assess the role of liraglutide in regulating iron metabolism in a mouse model of hereditary hemochromatosis.

30 Sep 2024

Advancements in AI-driven sensors transform pain management

A review paper by scientists at the Indiana University Bloomington summarized recent engineering eﬀorts in developing various sensors and devices for addressing challenges in the personalized treatment of pain.

27 Sep 2024

New insights into serine hydroxymethyltransferase aid cancer drug design

In just two neutron experiments, scientists discovered remarkable details about the function of an enzyme that can aid drug design for aggressive cancers.

26 Sep 2024

Childhood obesity: How the first 2,000 days hold the key to lifelong health

Researchers reveal that early life factors, especially within the first 2,000 days, play a critical role in shaping future obesity risk. Addressing these factors with integrated interventions could combat the global childhood obesity crisis.

26 Sep 2024

The potential to optimize laboratory testing and operations with automation and AI

In this interview, NewsMedical speaks with Cerba's Coen Staplers about the benefits of lab automation, including the integration of AI technologies.

From Cerba Research 25 Sep 2024

Study shows little rebound in cancer diagnoses post-pandemic

Cancer incidence trends in 2021 largely returned to what they were before the COVID-19 pandemic, according to a study by researchers at the National Institutes of Health (NIH).

24 Sep 2024

Study aims to uncover sex-specific causes of shoulder pain in wheelchair users

Josh Leonardis received funding from the Eunice Kennedy Shriver National Institute of Child Health and Human Development of the National Institutes of Health to study why female manual wheelchair users experience shoulder pain and pathology at greater rates than males.

23 Sep 2024

Seeing the unseen, together. 3DHISTECH and Barco at the 20th European Congress on Digital Pathology 2024

The ECDP 2024 event brings together experts, researchers, and industry leaders in the field of digital pathology. Join us from June 6th to June 8th in Vilnius, Lithuania, for an exciting collaboration that promises to advance research and innovation!

From 3DHISTECH 23 Sep 2024

Amyloid-β and tau disrupt brain activity, driving early cognitive decline in Alzheimer’s risk

Researchers discover how amyloid-β and tau pathologies interact to drive early neurophysiological changes and cognitive decline in older adults at risk of Alzheimer’s disease.

20 Sep 2024

Plasma pTau181 predicts Alzheimer’s progression in real-world memory clinic patients

Researchers confirm plasma pTau181 is a strong predictor for Alzheimer's in patients with mild cognitive impairment, offering a less invasive diagnostic tool for early intervention.

20 Sep 2024

Study reveals MYC gene's role in prostate cancer initiation and progression

By tracking the changes in prostate cancer cells over time, researchers at the Johns Hopkins Kimmel Cancer Center have found that activation of the MYC gene - a well-known cancer-causing gene - sets off a cascade of events that leads to both initiation and progression of the disease.

19 Sep 2024

$Cyberattacks plague the health industry. Critics call feds’ response feeble and fractured.$

Cyberattacks plague the health industry. Critics call feds’ response feeble and fractured.

Central Oregon Pathology Consultants has been in business for nearly 60 years, offering molecular testing and other diagnostic services east of the Cascade Range.

19 Sep 2024

Study highlights the importance of placental evaluation in pregnancy outcomes

In an opinion article publishing September 18 in the Cell Press journal Trends in Molecular Medicine, physician-scientists argue that with most placentas discarded after birth, placental pathology is underutilized clinically, should be a routine part of obstetric and neonatal care, and also deserves more research attention.

19 Sep 2024

New biomarkers offer hope for early detection and prevention of Alzheimer's

The failure to diagnose Alzheimer's disease, the most common form of dementia in the elderly, at an early stage of molecular pathology is considered a major reason why treatments fail in clinical trials. Previous research to molecularly diagnose Alzheimer's disease yielded "A/T/N" central biomarkers based on the measurements of proteins, β-amyloid ("A") and tau ("T"), and "N" encompassing neurodegeneration. A/T/N can be measured in brain tissue, by in vivo brain imaging techniques, and by analysis of cerebrospinal fluid and plasma.

18 Sep 2024

Understanding brain activity shifts in Alzheimer’s disease

Amyloid-beta and tau proteins have long been associated with Alzheimer's disease. The pathological buildup of these proteins leads to cognitive decline in people with the disease.

18 Sep 2024

Genome-wide association study identifies genetic risk factors for dementia

In landmark research, scientists at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) have reported the largest-ever genome-wide association study of dementia from all causes, revealing an overlap of genetic risks including neurodegeneration, vascular factors and cerebral small-vessel disease.

18 Sep 2024

Study uncovers ancestry-specific genetic links to multiple sclerosis risk

A landmark study has uncovered novel ancestry-specific genetic variants linked to multiple sclerosis (MS), offering new insights that could reshape treatment approaches for diverse populations affected by the disease.

17 Sep 2024

3D mammograms show greater accuracy in detecting breast cancer

The newer, 3D form of breast screening, known as digital breast tomosynthesis (DBT), is more effective at detecting breast cancer than traditional 2D digital mammography (DM).

17 Sep 2024