Immune System News and Research

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Maternal infections during pregnancy may alter genes key to prenatal brain development

If a mother picks up an infection during pregnancy, her immune system will kick into action to clear the infection - but this self-defence mechanism may also have a small influence how her child's brain develops in the womb, in ways that are similar to how the brain develops in autism spectrum disorders.

21 Mar 2017

Penn scientists discover method that appears to provide early warning of transplant rejection

Approximately 30,000 organ transplants occur in the United States each year. However, between 20 and 50 percent—depending on the organ type—of the transplanted organs fail within five years, most often because the recipient's immune system attacks, or "rejects," the donated organ.

21 Mar 2017

Research findings hold promise to generate blood cell precursors from hPSCs

The Galat laboratory at Stanley Manne Children's Research Institute, Ann & Robert H. Lurie Children's Hospital of Chicago, has developed an elegant system to derive blood cell precursors from human pluripotent stem cells (hPSC).

21 Mar 2017

Scientists use parsley and other plants to create human stem cell scaffolds

Borrowing from nature is an age-old theme in science. Form and function go hand-in-hand in the natural world and the structures created by plants and animals are only rarely improved on by humans.

21 Mar 2017

Salk scientists develop new way to find responders to lithium therapy

For roughly one-third of people diagnosed with bipolar disorder, lithium is a miracle drug, effectively treating both their mania and depression. But once someone is diagnosed, it can take up to a year to learn whether that person will be among the 30 percent who respond to lithium or the 70 percent who do not.

21 Mar 2017

Duke scientists use mathematical tools to track how microbial evolution unfolded

As the human species evolved over the last six million years, our resident microbes did the same, adapting to vastly different conditions on our skin and in our mouths, noses, genitalia and guts.

21 Mar 2017

Scientists identify molecules that may be key to drug resistance in estrogen-driven breast cancers

Three-quarters of all breast cancer tumors are driven by the hormone estrogen. These tumors are frequently treated with drugs to suppress estrogen receptor activity, but unfortunately, at least half of patients do not respond to these treatments, leaving them with drug-resistant tumors and few options.

20 Mar 2017

Novel technology enables systematic analysis of linear ubiquitination targets

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many different forms, either as single molecule or in the form of distinct ubiquitin chains, leading to diverse conformations and varying cellular outcomes.

20 Mar 2017

Study shows potential way to prevent formation of scar tissue around medical implants

Medical devices implanted in the body for drug delivery, sensing, or tissue regeneration usually come under fire from the host's immune system.

20 Mar 2017

Study sheds light on cellular mechanisms that enable prostate cancer cells to form secondary tumours

New King's College London research sheds light on the cellular mechanisms which enable cancer cells to escape the prostate and spread to other parts of the body.

20 Mar 2017

MIT researchers devise new strategy to make tumor cells more susceptible to cancer treatment

MIT researchers have devised a way to make tumor cells more susceptible to certain types of cancer treatment by coating the cells with nanoparticles before delivering drugs.

20 Mar 2017

Early treatment with stem cells can safely help recovery in stroke patients, study shows

A multicenter trial looking at whether a single dose of millions of adult, bone-marrow-derived stem cells can aid stroke recovery indicates it's safe and well-tolerated by patients but may not significantly improve their recovery within the first three months, researchers report.

20 Mar 2017

Study finds 18% increase in HIV treatment success rates

Researchers have been successful in increasing HIV treatment success rates by almost 18 percent.

20 Mar 2017

Linking RNA to autoimmune diseases

An interview with Dr. Chase Spurlock, CEO, discussing IQuity's research into IncRNAs and how they are linked to autoimmue diseases.

20 Mar 2017

Combination approach holds potential for treating lung cancer patients

An emerging approach for cancer treatment seeks to combine radiation therapy with immune checkpoint inhibitors to more effectively control tumors in the chest with an acceptable risk of severe treatment-related side effects.

17 Mar 2017

Immune cells could be new target to treat type 2 diabetes, hypertension in overweight people

Immune cells which are reduced in number by obesity could be a new target to treat diseases such as type 2 diabetes and hypertension that affect overweight people, according to a collaborative study between The University of Manchester, Lund University and the University of Salford.

From The University of Manchester 17 Mar 2017

Better understanding of pre-metastatic niches could lead to new preventive therapies

Metastasis is the major cause of cancer-related death and its appearance remains a phenomenon that is difficult to predict and manage.

17 Mar 2017

Nocturia is the top cause of sleep disturbance

‘On World Sleep Day sleep experts encourage people to understand the value of healthy and solid sleep. In particular, if they need to go to the toilet more than once in the night they have nocturia, a condition which affects one in three adults over the age of 30 and two thirds of adults over the age of 65.’

17 Mar 2017

Scientists identify genetic clues to chronic kidney disease

Using international genomic studies backed by proof-of-concept cell experiments, researchers have identified two genes that contribute to the chronic kidney disease glomerulonephritis.

16 Mar 2017

Young researchers explore impact of prolonged Zika viremia in pregnant women, fetuses and infants

A Maryland woman traveled to the Dominican Republic early in her pregnancy, spending three weeks with family. She felt dizzy and tired and, at first, attributed the lethargy to jet lag.

16 Mar 2017

Immune System News and Research

Maternal infections during pregnancy may alter genes key to prenatal brain development

Penn scientists discover method that appears to provide early warning of transplant rejection

Research findings hold promise to generate blood cell precursors from hPSCs

Scientists use parsley and other plants to create human stem cell scaffolds

Salk scientists develop new way to find responders to lithium therapy

Duke scientists use mathematical tools to track how microbial evolution unfolded

Scientists identify molecules that may be key to drug resistance in estrogen-driven breast cancers

Novel technology enables systematic analysis of linear ubiquitination targets

Study shows potential way to prevent formation of scar tissue around medical implants

Study sheds light on cellular mechanisms that enable prostate cancer cells to form secondary tumours

MIT researchers devise new strategy to make tumor cells more susceptible to cancer treatment

Early treatment with stem cells can safely help recovery in stroke patients, study shows

Study finds 18% increase in HIV treatment success rates

Linking RNA to autoimmune diseases

Combination approach holds potential for treating lung cancer patients

Immune cells could be new target to treat type 2 diabetes, hypertension in overweight people

Better understanding of pre-metastatic niches could lead to new preventive therapies

Nocturia is the top cause of sleep disturbance

Scientists identify genetic clues to chronic kidney disease

Young researchers explore impact of prolonged Zika viremia in pregnant women, fetuses and infants

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