Critical Care News and Research

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Unified global scoring system urgently needed for intensive care

Assessing the severity of illness in critically ill patients is a crucial task in Intensive Care Units (ICUs) worldwide.

19 Nov 2025

Machine learning tool helps evaluate ICU resource efficiency in severe pneumonia care

A study published in the Journal of Critical Care, conducted with the participation of the D'Or Institute for Research and Education (IDOR), investigated how to measure efficiency in the use of resources for patients with severe community-acquired pneumonia (CAP), an illness contracted outside hospital settings and most common among older adults.

18 Nov 2025

Muscle-driven gene therapy shows promise for protecting memory in Alzheimer’s

Alzheimer's disease (AD) is a devastating cause of memory loss and cognitive decline, for which no curative treatment is available.

18 Nov 2025

Evolving epidemiology of invasive Group A Streptococcus in critical care

Streptococcus pyogenes or invasive Group A Streptococcus (iGAS) is a major clinical concern around the world, since iGAS infections can quickly escalate into life-threatening conditions such as necrotizing fasciitis, septic shock, and pneumonia.

6 Nov 2025

Inhibiting ferroptosis suppressor protein 1 shrinks lung cancers in mice

NYU Langone Health researchers found that a type of cell death caused by a buildup of highly reactive molecules suppresses lung tumor growth.

5 Nov 2025

Familiar voices help reduce the risk of delirium in ICU patients

The innovative use of recorded messages from a family member to provide reorientation information to a critically ill patient receiving mechanical ventilation helped reduce the risk of developing delirium, according to new research published in American Journal of Critical Care (AJCC).

3 Nov 2025

Understanding how biological sex and gender inequities contribute to suboptimal sepsis treatment

Sepsis continues to be a leading cause of mortality in ICUs worldwide. Despite advances in early detection and treatment, standardized antibiotic dosing frequently ignores patient-level variability-especially that associated with sex-related physiology and gender-influenced care disparities.

31 Oct 2025

Study sheds light on the practice patterns of aerosol drug therapy in patients with ARDS

A new review led by Associate Professor Sanjay Singhal from Dr. Ram Manohar Lohia Institute of Medical Sciences sheds light on the prevalence and practice patterns of ADT in patients with ARDS.

29 Oct 2025

Lundquist Institute researcher awarded NIH funding to advance ICU care for critically ill patients

The Lundquist Institute is proud to announce that Dong Chang, MD, MS has been awarded a prestigious R01 grant from the National Institutes of Health (NIH)/National Institute on Aging, totaling $3,163,459, for his groundbreaking project entitled: "A Type 2 Hybrid Effectiveness-Implementation Study of Time-Limited Trials to Reduce Potentially Non-Beneficial Treatments for Critically Ill Patients with Advanced Medical Illnesses."

27 Oct 2025

Intraoperative music therapy reduces anesthetic use and physiological stress

A groundbreaking study published in the peer-reviewed journal Music and Medicine demonstrates that intraoperative music therapy significantly reduces the amount of propofol and fentanyl required during laparoscopic cholecystectomy performed under general anesthesia.

27 Oct 2025

Updated guidelines published for pediatric CPR and emergency cardiovascular care

The American Academy of Pediatrics and the American Heart Association (the Association), a relentless force changing the future of health for everyone everywhere, have published updated guidelines for cardiopulmonary resuscitation and emergency cardiovascular care for newborn and pediatric populations.

24 Oct 2025

New BRIGHT Center aims to build resilience after trauma

The Medical University of South Carolina has been awarded more than $11 million by the National Institute of General Medical Sciences over five years to establish a Center of Biomedical Research Excellence (COBRE) to build resilience after trauma, which will be known as the South Carolina Building Resilience through Innovative Interventions to promote Growth and Health after Trauma COBRE, or the BRIGHT Center.

24 Oct 2025

New guidelines aid parents and clinicians in pediatric tracheotomy decisions

The emotional strain on parents and other caregivers faced with deciding whether a tracheotomy is the best treatment for their child is hard to measure. The latest clinical practice guideline from the American Thoracic Society aims to give clinicians and parents/caregivers a way forward so they can navigate difficult decisions to ensure better outcomes for young patients. The guideline was published early online today, Wednesday, Oct. 22, in the American Journal of Respiratory and Critical Care Medicine.

23 Oct 2025

Updated CPR guidelines provide expanded recommendations for managing choking and opioid overdose

The "2025 American Heart Association Guidelines for Cardiopulmonary Resuscitation (CPR) and Emergency Cardiovascular Care (ECC)," published today in the Association's flagship journal, Circulation, marks the first full revision of lifesaving resuscitation guidance since 2020.

22 Oct 2025

Neighborhood environments can influence a child's risk of developing type 2 diabetes

Type 2 diabetes (T2D), once considered an adult-onset disease, is increasing at alarming rates in children and adolescents. Before the mid-1990s, just 1% to 2% of youth with diabetes had T2D.

21 Oct 2025

Blocking key protein restores healthy lung function and reduces fibrosis in mice

Pulmonary fibrosis is a deadly disease in which the lungs become thickened and scarred, gradually losing their ability to deliver oxygen to the body.

16 Oct 2025

New breakthrough enables whole genome sequencing in hours

Boston Children's Hospital, along with Broad Clinical Labs and Roche Sequencing Solutions, has demonstrated that rapid genomic sequencing and interpretation are achievable in a matter of hours.

16 Oct 2025

Study provides a roadmap for how health systems can improve lung cancer screening rates

Lung cancer screening might be the best-kept secret in health care today. Only about 16 percent of those who are eligible in the U.S. get screened for lung cancer, but a study coming out in NEJM Catalyst on Wednesday provides a roadmap for how health systems can improve those numbers.

15 Oct 2025

Children living near the Salton Sea face declining lung function

Children living near the Salton Sea, in Southern California's desert region of Imperial County, are experiencing poorer lung function than children exposed to less wind-blown dust, according to a new study led by researchers at the University of California, Irvine's Joe C. Wen School of Population & Public Health.

14 Oct 2025

HEPA purifiers do not fully reduce classroom viral exposure

In a secondary analysis of a study of 200 classrooms, Mass General Brigham researchers found respiratory viral exposures were still high in those with HEPA purifiers, suggesting additional interventions are needed.

10 Oct 2025