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3D-printed scaffolds use shape memory to heal infected bone defects

Infected bone defects arise in conditions such as osteomyelitis and post-traumatic bone infections, where microbial persistence and immune imbalance prevent effective healing.

4 Mar 2026

Researchers identify TRIM13 protein as key driver of immune suppression in sepsis

Dendritic cells (DCs) are increasingly recognized as important contributors to sepsis-associated immune dysfunction.

4 Mar 2026

Nonadherence to COPD medication increases hospital admissions and mortality

Medication nonadherence among people with chronic obstructive pulmonary disease (COPD) is a result of affordability and lack of knowledge about medications, among other factors, and leads to increased exacerbations and faster lung function decline, according to two new studies.

4 Mar 2026

Gut microbiota-derived metabolite directly shapes immune responses in bacterial pneumonia

Sepsis and severe pneumonia are frequently accompanied by disruption of the gut microbiota, leading to immune dysfunction and increased susceptibility to secondary infections.

4 Mar 2026

NLRP3 inflammasome plays dual, time-dependent roles during acute wound healing

Wound healing is a multistep biological process involving inflammation, tissue formation, and remodeling.

2 Mar 2026

American College of Chest Physicians announces CCAPP designation for advanced practice providers

The American College of Chest Physicians (CHEST) is pleased to announce the first class of advanced practice providers (APPs) to earn the CHEST Critical Care Advanced Practice Provider (CCAPP) designation.

19 Feb 2026

New guidelines outline comprehensive care for acute pulmonary embolism

Early detection and prompt treatment of acute pulmonary embolism (PE), a sudden and potentially life-threatening blood clot that blocks arteries in the lungs, is critical.

19 Feb 2026

Neighborhood poverty, uninsured status linked to COPD hospitalizations

Certain neighborhood characteristics, including higher poverty, more uninsured residents, and lower educational attainment, may lead to an increase in COPD-related emergency department visits and hospitalizations, according to a new study in the January 2026 issue of Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation, a peer-reviewed, open access journal.

19 Feb 2026

Redefining cardiovascular care for women

Cardiovascular disease (CVD) remains the leading cause of death for women across the globe, yet significant progress has been made in prevention, diagnosis and management thanks to more sex-specific research, as noted in a special Go Red for Women issue of Circulation, the American Heart Association's flagship, peer-reviewed scientific journal, published today.

17 Feb 2026

Prehospital emergency anesthesia with intubation saves lives of trauma patients

Trauma patients urgently requiring a breathing tube are more likely to survive if the tube is inserted before arriving at hospital compared to insertion afterwards, suggests a modeling study led by researchers at University College London (UCL) and the Severn Major Trauma Network.

12 Feb 2026

Blood omics data forecasts trauma outcomes with high accuracy

Researchers at the University of Colorado Anschutz have developed a way to predict how trauma patients will recover, days before complications come to fruition, by analyzing the molecules in their blood.

11 Feb 2026

Novel computational framework developed for real-time, personalized heart rate variability monitoring

Real-time and early detection of minute changes in the functioning of the cardiovascular system is crucial for managing critically ill patients, such as newborns and older adults, and can significantly affect their outcomes.

10 Feb 2026

Study reveals how two key proteins contribute to abnormal bone growth after injury

After serious injuries, burns, fractures, or major surgeries, the body normally repairs damaged tissues and restores movement.

9 Feb 2026

UK air ambulance critical care expands but unequal access still limits lifesaving treatment

A national UK survey found physician-based helicopter emergency medical services have expanded substantially since 2009, with more teams and improved overnight coverage. However, geographic and time-of-day disparities persist, and variation in funding, staffing, and interventions continues to affect equitable access to advanced prehospital care.

8 Feb 2026

Early tuberculosis treatment reduces sepsis deaths in HIV patients

Sepsis is a leading global cause of hospital deaths, occurring when the body's response to infection damages tissue and causes organs to fail. Africa bears the world's highest burden of sepsis, with an estimated 48 million cases each year leading to about 11 million deaths.

7 Feb 2026

UK air ambulance availability improves yet critical gaps continue

Despite significant improvements in the availability of 24/7 emergency air ambulance services (HEMS) across the UK since 2009, persistent regional gaps remain, finds research published online in Emergency Medicine Journal.

3 Feb 2026

Targeted PICU rounds reduce the rate of healthcare-associated conditions

Rounds focused on critically ill pediatric patients at the greatest risk for developing healthcare-associated conditions (HACs) reduced the rate of specific HACs by nearly 50% at a Colorado hospital, according to a study published in Critical Care Nurse (CCN).

3 Feb 2026

High-dose inhaled nitric oxide could fight multidrug-resistant infections

Overuse of antibiotics has accelerated the development of bacterial resistance to conventional drugs, a global health crisis projected to result in more than 10 million deaths annually by 2050.

21 Jan 2026

Pulse oximeters miss hypoxemia more often in people with darker skin, study finds

This large prospective UK study compared five low-cost fingertip pulse oximeters with arterial blood gas measurements and found that readings varied systematically by skin tone and oxygen saturation level. Small average overestimations in darker skin translated into clinically meaningful increases in missed hypoxemia at commonly used SpO2 thresholds.

18 Jan 2026

New CHEST guidelines offer evidence-based biologic selection for severe asthma

The American College of Chest Physicians (CHEST) recently released a new clinical guideline on biologic management in severe asthma.

13 Jan 2026

Critical Care News and Research

3D-printed scaffolds use shape memory to heal infected bone defects

Researchers identify TRIM13 protein as key driver of immune suppression in sepsis

Nonadherence to COPD medication increases hospital admissions and mortality

Gut microbiota-derived metabolite directly shapes immune responses in bacterial pneumonia

NLRP3 inflammasome plays dual, time-dependent roles during acute wound healing

American College of Chest Physicians announces CCAPP designation for advanced practice providers

New guidelines outline comprehensive care for acute pulmonary embolism

Neighborhood poverty, uninsured status linked to COPD hospitalizations

Redefining cardiovascular care for women

Prehospital emergency anesthesia with intubation saves lives of trauma patients

Blood omics data forecasts trauma outcomes with high accuracy

Novel computational framework developed for real-time, personalized heart rate variability monitoring

Study reveals how two key proteins contribute to abnormal bone growth after injury

UK air ambulance critical care expands but unequal access still limits lifesaving treatment

Early tuberculosis treatment reduces sepsis deaths in HIV patients

UK air ambulance availability improves yet critical gaps continue

Targeted PICU rounds reduce the rate of healthcare-associated conditions

High-dose inhaled nitric oxide could fight multidrug-resistant infections

Pulse oximeters miss hypoxemia more often in people with darker skin, study finds

New CHEST guidelines offer evidence-based biologic selection for severe asthma

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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