Myelin News and Research

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Myelin is the fatty substance that covers and protects nerves.

Marathon running temporarily reduces brain myelin levels

Marathon running causes a temporary decline in brain myelin content, but levels return to normal within two months. This reversible change may reflect the brain tapping into myelin lipids as an emergency energy source during extreme exertion.

25 Mar 2025

IL-12 targeting could open pathways for new Alzheimer's treatments

Researchers from Charité – Universitätsmedizin Berlin and the Max Delbrück Center have detailed the precise mechanism through which the inflammatory signaling molecule IL-12 contributes to Alzheimer's disease.

17 Mar 2025

Study reveals how silent X chromosome enhances female brain resilience

In a surprise, work in mice has found that the dormant X chromosome in females can reawaken late in life and turn on genes that keep the brain healthy.

6 Mar 2025

New MS research harnessing the brain's healing power

A new multiple sclerosis (MS) research project designed to help the brain repair itself by activating its own healing processes has been announced as part of MS Australia's latest $5.7 million research investment.

5 Mar 2025

Non-invasive 40Hz gamma stimulation could help fight Alzheimer’s

A decade after scientists in The Picower Institute for Learning and Memory at MIT first began testing whether sensory stimulation of the brain's 40Hz "gamma" frequency rhythms could treat Alzheimer's disease in mice, a growing evidence base supporting the idea that it can improve brain health-in humans as well as animals-has emerged from the work of labs all over the world.

3 Mar 2025

The brain-gut microbiota axis: Impact on mental health & potential treatment avenues

To be decided by the editor

From Atlantia Clinical Trials 28 Feb 2025

New brain map reveals insights into multiple sclerosis development

NIH study reveals key players underlying disease onset and repair.

27 Feb 2025

Common medications disrupt brain development by affecting sterol biosynthesis

In a peer-reviewed Perspective (review) article, researchers at the University of Nebraska Medical Center have uncovered concerning evidence that commonly prescribed medications may interfere with crucial brain development processes by disrupting sterol biosynthesis.

25 Feb 2025

"Normal" vitamin B12 levels may not prevent brain decline

Researchers identify associations between B12 levels currently accepted as normal and markers of neurological injury or impairment.

24 Feb 2025

Study shows promise for new treatment approach for multiple sclerosis

A sponge-like implant in mice helped guide a treatment that slowed or stopped a degenerative condition similar to multiple sclerosis in humans. It also gave University of Michigan researchers a first look at how primary progressive multiple sclerosis, the fastest-progressing version of the disease, attacks the central nervous system early on.

19 Feb 2025

Researchers identify MLC1 as potential target in multiple sclerosis

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system caused by the immune system. B cells, which are a type of white blood cell, play a role in the development of MS and are thus a target for therapies.

18 Feb 2025

Discovery of gene silencer offers hope for autosomal dominant leukodystrophy

A team led by University of Pittsburgh School of Public Health geneticists has shown, for the first time, that a gene "silencer" that resides in junk DNA is directly sparing people from a devastating and fatal progressive neurological disease.

13 Feb 2025

New drug candidate shows potential to restore vision in people with MS

Researchers at the University of Colorado Anschutz Medical Campus have found a promising drug candidate that could help restore vision in individuals with multiple sclerosis (MS) and other neurological conditions that damage neurons.

24 Jan 2025

Brain Bank tissue samples unlock key findings about stroke-induced damage and repair

A new study by researchers at the Department of Molecular Medicine at SDU sheds light on one of the most severe consequences of stroke: damage to the brain's "cables"-the so-called nerve fibers-which leads to permanent impairments.

24 Jan 2025

Exercise offers hope in the Alzheimer's battle

Regular aerobic exercise could significantly reduce disease markers associated with Alzheimer's, new research led by scientists at the University of Bristol (UK) and the Federal University of São Paulo (Brazil) has found. The findings provide new hope in the battle against this devastating disorder.

16 Jan 2025

Pheno Therapeutics receives clinical trial authorization for novel multiple sclerosis therapeutic

Pheno Therapeutics Limited., a biotechnology company focused on the discovery and development of small molecule therapeutics for the treatment of neurological diseases, announced today it has received clinical trial authorization (CTA) from the UK’s MHRA (Medicines and Healthcare products Regulatory Agency) for its lead candidate, PTD802.

15 Jan 2025