Organic chemistry News and Research

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Scientists uncover new method to produce compounds with anti-cancer properties

In the past decades, cancer has surpassed many other diseases to become the current second leading cause of death globally, with one in six people dying from it.

17 Nov 2020

Study describes the effects of a DPP3-knockout on the renin-angiotensin system

The role of the enzyme dipeptidyl peptidase 3 in the blood pressure-regulating renin-angiotensin system was investigated in the inter-university cooperation project BioTechMed-Graz. The results could pave the way for new therapies for cardio-renal diseases.

5 Nov 2020

Scientists identify new target for developing novel drugs against several types of cancer

The Bcl-2 protein family comprises anti- and proapoptotic members, i.e. they protect the cell from death or favour it.

27 Oct 2020

New machine learning concepts can help develop novel drugs

Tandem mass spectrometry is a powerful analytical tool used to characterize complex mixtures in drug discovery and other fields.

14 Oct 2020

Chemists suggest a new domino reaction to produce organic compounds against cancers

A team of chemists from RUDN University suggested a new reaction to produce organic compounds in one vessel.

9 Oct 2020

DARPA selects Purdue-affiliated company to develop continuous manufacturing technology

The COVID-19 pandemic has created supply chain gaps in critical drug products, especially those needed for the most critical patients in intensive care units across the country.

7 Oct 2020

New book provides data about synthesis and relevant nucleophilic reactions for perhalopyridines

Halogenated pyridines can be used as interesting starting materials in a wide range of organic synthesis methods.

23 Sep 2020

DNA damage may occur far away from the point of incidence of radiation

Ultraviolet light endangers the integrity of human genetic information and may cause skin cancer. For the first time, researchers of Karlsruhe Institute of Technology have demonstrated that DNA damage may also occur far away from the point of incidence of the radiation.

14 Sep 2020

New bio-active natural products with huge potential as drugs

Natural compounds continue to play a key role in drug development. Many clinically approved drugs are either unmodified natural products or their semi-synthetic derivatives.

8 Sep 2020

UV researchers patent a kit to detect GHB in alcoholic beverages and soft drinks

The MODeLiC (Organic Materials for Controlled Detection and Release) research team led by Ana María Costero, Professor of Organic Chemistry at the University of Valencia (UV), has developed a system with colorimetric sensors that change color when there is γ-hydroxybutyric acid (GHB) in a beverage.

8 Sep 2020

FlowSyn system enables rapid evaluation of critical reactions

Uniqsis reports how a FlowSyn™ continuous flow reactor installed at Adesis Inc. of New Castle, DE (USA) is assisting them in evaluating custom synthetic routes for compounds along with improving existing batch manufacturing processes.

From Uniqsis Ltd 3 Sep 2020

Improved type of PROTAC enhances intracellular accumulation and protein knockdown

Cancer therapies sometimes involve drugs that mediate the breakdown of specific intracellular proteins that participate in cancer formation and proliferation.

27 Aug 2020

New book series advances the development of pharmaceutical agents for treating neurological, CNS disorders

Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders.

21 Aug 2020

Organic chemistry News and Research

Scientists uncover new method to produce compounds with anti-cancer properties

Study describes the effects of a DPP3-knockout on the renin-angiotensin system

Scientists identify new target for developing novel drugs against several types of cancer

New machine learning concepts can help develop novel drugs

Chemists suggest a new domino reaction to produce organic compounds against cancers

DARPA selects Purdue-affiliated company to develop continuous manufacturing technology

New book provides data about synthesis and relevant nucleophilic reactions for perhalopyridines

DNA damage may occur far away from the point of incidence of radiation

New bio-active natural products with huge potential as drugs

UV researchers patent a kit to detect GHB in alcoholic beverages and soft drinks

FlowSyn system enables rapid evaluation of critical reactions

Improved type of PROTAC enhances intracellular accumulation and protein knockdown

New book series advances the development of pharmaceutical agents for treating neurological, CNS disorders

Scientists design new catalyst to widen the range of target chemical substances for radical reactions

Existing drug used to treat alcoholism is potentially effective against COVID-19

Chlamydiae need a lot of glutamine to multiply in human cells

Scientists identify cellular mechanism that shows promise in treating cancer

Modern mass spectrometry applications in research

Researchers discover novel class of safer analgesics

Synthesis of bioactive natural compounds for the battle against cancer

Industry Focus eBook - Cell biology (5th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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