Efficacy News and Research

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Study shows benefits of delayed-release stimulant in children with ADHD

A phase 3 study of children ages 6-12 years with attention deficit/hyperactivity disorder (ADHD) has shown that a delayed-release, long-acting formulation of the stimulant methylphenidate, when taken in the evening, led to significant improvement in ADHD symptoms and functional impairment first thing the next morning, compared to a placebo.

27 Sep 2017

SBP researcher awarded $10.8 million grant to pursue development of new drug for substance abuse

Sanford Burnham Prebys Medical Discovery Institute is pleased to announce the National Institute on Drug Abuse at the National Institutes of Health has awarded Nicholas Cosford, Ph.D., a three-year, $10.8 million grant to pursue the preclinical development of a new class of medicine to treat substance use disorders.

26 Sep 2017

Researchers use multi-modal integrated approach to develop potential anti-Chagas therapies

Chagas disease is a potentially life-threatening illness caused by the parasite, Trypanosoma cruzi, and is transmitted to humans through triatomine blood-sucking bugs that are commonly referred to as "kissing bugs" or "vampire bugs".

26 Sep 2017

Biomaterial-mediated growth factor delivery can restore perfusion of blood vessels in animal models

Ischemia is a serious medical condition in which the flow of blood and delivery of oxygen to tissues is restricted, thus resulting in pain, weakness, and more seriously, tissue and organ damage. Ischemia in muscle tissue, most commonly as a result of atherosclerosis, leads to life-threatening diseases like coronary artery disease and stroke, but also to chronic peripheral artery disease (PAD).

26 Sep 2017

New gel patch could speed up healing and minimize formation of scars

Scientists from Nanyang Technological University, Singapore have developed a new gel patch prototype that could speed up the healing of a skin wound while minimizing the formation of scars. The team unveiled the patch today as a proof-of-concept.

25 Sep 2017

Researchers use gene therapy to restore hearing and balance in mouse model of Usher syndrome

Hearing loss, sometimes associated with other disorders such as balance defects, is the most common sensory deficit, affecting more than 280 million people worldwide, according to WHO. In France, one child in 700 is born with severe or profound hearing loss, and one in every 1,000 will lose their sense of hearing before adulthood.

22 Sep 2017

Research confirms smartphone apps as effective treatment option for depression

New Australian-led research has confirmed that smartphone apps are an effective treatment option for depression, paving the way for safe and accessible interventions for the millions of people around the world diagnosed with this condition.

22 Sep 2017

New tissue-chip research aims to speed drug development for two genetic forms of epilepsy

An interdisciplinary team of Vanderbilt University researchers has received a two-year, $2-million federal grant to develop an "organ-on-chip" model for two genetic forms of epilepsy. These disorders affect both brain and heart and improved modeling could lead to new drug treatments.

22 Sep 2017

Diet and exercise have potential to improve chemotherapy effectiveness in pediatric cancer patients

Diet and exercise may improve treatment outcomes in pediatric cancer patients, according to a study at The University of Texas MD Anderson Children's Cancer Hospital.

21 Sep 2017

Small-molecule immunotherapeutics could steer immune defense against fungal pathogens

Fungal infections represent an increasing health crisis, especially for immune-deficient patients. American scientists now report in the journal Angewandte Chemie that specific help could be provided by small-molecule immunotherapeutics with novel mechanism of action.

21 Sep 2017

BMC researchers studying possibility of weight loss drugs to combat cocaine addiction

Boston Medical Center's psychiatry team is studying a drug called lorcaserin, which targets the brain's serotonin receptors and could help reduce cocaine cravings as well as dampen the rewards associated with taking cocaine.

21 Sep 2017

New man-made antioxidant could help improve success rates of cell-based therapies

Cell therapies being developed to treat a range of conditions could be improved by a chemical compound that aids their survival, research suggests.

19 Sep 2017

QMUL professor receives Cancer Research UK Lifetime Achievement Award

Professor Jack Cuzick from Queen Mary University of London has received the Cancer Research UK Lifetime Achievement Award for his work on cancer prevention and detection.

19 Sep 2017

Carbohydrates on surface of malaria parasites could be key to effective vaccine

An international research team has shown for the first time that carbohydrates on the surface of malaria parasites play a critical role in malaria's ability to infect mosquito and human hosts.

18 Sep 2017

A skin patch to get rid of those love handles

Researchers from the Columbia University Medical Center (CUMC) and the University of North Carolina have managed to devise a microneedle skin patch that could locally treat both obesity and diabetes. As of now it has been used to treat mice in the laboratory and shown promising results.

17 Sep 2017

Categories of Preference included for recommendations within NCCN Guidelines

The National Comprehensive Cancer Network has instituted Categories of Preference for recommendations within the NCCN Clinical Practice Guidelines in Oncology. Initially, Categories of Preference will be published for drugs and biologics recommended within the NCCN Guidelines® for Multiple Myeloma.

15 Sep 2017

Study examines effectiveness of placebo and antidepressants in children, adolescents

Although the clinical efficacy of antidepressants in children and adolescents is proven, it is frequently accompanied by side effects. In addition, the influence of the placebo effect on the efficacy of antidepressants is unclear.

15 Sep 2017

Study highlights complexity of childhood cancer survivors’ medical needs

Survivors of childhood cancer may experience, on average, nearly twice as many chronic health condition by the age of 45, compared to the general population, according to a new study led by St Jude Children’s Research Hospital (USA) and published in The Lancet.

15 Sep 2017

Researchers identify natural compound that appears to shut down cancer cells' energy source

The Warburg Effect describes a phenomenon in which cancer cells voraciously consume glucose for energy -- something scientists have long known, yet have had little success exploiting as a way to stunt tumor growth.

14 Sep 2017

New clinical trial begins testing Epigem’s instrument for detection, cure of rare anemias

Epigem today announced that one of its development instruments, MeChem, is being tested in a new clinical trial into the detection and cure of rare anemias. The company has filed two patents relating to the test methods and the associated system.

14 Sep 2017

Efficacy News and Research

Study shows benefits of delayed-release stimulant in children with ADHD

SBP researcher awarded $10.8 million grant to pursue development of new drug for substance abuse

Researchers use multi-modal integrated approach to develop potential anti-Chagas therapies

Biomaterial-mediated growth factor delivery can restore perfusion of blood vessels in animal models

New gel patch could speed up healing and minimize formation of scars

Researchers use gene therapy to restore hearing and balance in mouse model of Usher syndrome

Research confirms smartphone apps as effective treatment option for depression

New tissue-chip research aims to speed drug development for two genetic forms of epilepsy

Diet and exercise have potential to improve chemotherapy effectiveness in pediatric cancer patients

Small-molecule immunotherapeutics could steer immune defense against fungal pathogens

BMC researchers studying possibility of weight loss drugs to combat cocaine addiction

New man-made antioxidant could help improve success rates of cell-based therapies

QMUL professor receives Cancer Research UK Lifetime Achievement Award

Carbohydrates on surface of malaria parasites could be key to effective vaccine

A skin patch to get rid of those love handles

Categories of Preference included for recommendations within NCCN Guidelines

Study examines effectiveness of placebo and antidepressants in children, adolescents

Study highlights complexity of childhood cancer survivors’ medical needs

Researchers identify natural compound that appears to shut down cancer cells' energy source

New clinical trial begins testing Epigem’s instrument for detection, cure of rare anemias

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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