Protein C News and Research

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Quantum mechanical model offers insights into SARS-CoV-2 evolution

Researchers used an ab initio full quantum mechanical model to characterize the spike protein RBD interactions with host cells and gain mechanistic insights into SARS-CoV-2 evolution.

3 Dec 2021

Characterization of two novel SARS-CoV-2 delta variant sublineages

Researchers characterized the two novel AY.43 sublineages of the SARS-CoV-2 delta variant with probable Brazilian origin.

3 Dec 2021

Novel peptide-antibody fusion molecule enhances SARS-CoV-2 variant neutralization

A recent study reports neutralizing efficacy for a fused peptide-antibody molecule against SARS-CoV-2, providing hope that therapeutic neutralizing antibodies may soon be available.

3 Dec 2021

Maternal anemia during pregnancy may increase risk of childhood anemia

Babies born to women with anemia during pregnancy have an increased risk of childhood anemia, according to a study carried out in rural India.

2 Dec 2021

Cedars-Sinai researchers uncover the cause of UTI-induced delirium

Cedars-Sinai researchers have found that blocking the action of a protein called interleukin 6 (IL-6), part of the immune system, could resolve the delirium that often accompanies urinary tract infection (UTI) in elderly patients.

2 Dec 2021

Link between tobacco product use and alcohol consumption with anti-SARS-CoV-2 antibody titers after BNT162b2 vaccine

In a Japanese study, smoking, HNB tobacco products, and alcohol use have been shown to impair the immunological response to the COVID-19 vaccination.

2 Dec 2021

Study documents and visualizes hearing loss-associated genes in the inner ear

Researchers from Uppsala University have been able to document and visualise hearing loss-associated genes in the human inner ear, in a unique collaboration study between otosurgeons and geneticists.

2 Dec 2021

Non-coding RNA plays a key role in regulating behavior of chromosome loops and gene expression

An important player in the healthy development of female embryos turns out also to play a key role in regulating the behavior of chromosome loops and gene expression in both sexes, according to a new study by researchers at Massachusetts General Hospital.

2 Dec 2021

Men with inherited gene mutation have high risk of aggressive prostate cancer

Men who inherit mutations in a gene called TP53 have a high risk of developing aggressive prostate cancer, a multicenter research team in the United States has found.

2 Dec 2021

Genetic variant found in Old Order Amish may confer protective effects against cardiovascular disease

Whole-exome sequencing and association analysis in nearly 7,000 Old Order Amish reveals a genetic variant that may confer protective effects against cardiovascular disease (CVD), researchers report.

2 Dec 2021

New bioinformatics method for viral sgRNA analysis

A recent study discusses a bioinformatics method to help identify and explore sgRNAs uncovered in next-generation sequencing data.

2 Dec 2021

Large study of plasma proteome unravels its genetic determinants and relationship with human disease

In a study published today in Nature Genetics, scientists at deCODE genetics , a subsidiary of the pharmaceutical company Amgen, demonstrate how measuring the levels of a large number of proteins in plasma at population scale when combined with data on sequence diversity and RNA expression dramatically increases insights into human diseases and other phenotypes.

2 Dec 2021

Systematic survey of human SARS-CoV-2 monoclonal antibodies

Scientists have mined information from several research publications and patents to create a dataset of approximately 8000 human antibodies to the SARS-CoV-2 spike from more than 200 donors.

2 Dec 2021

Study suggests efficacy of SARS-CoV-2 main protease inhibitors is not compromised in current COVID-19 variants

A new study has focussed on assessing the Mpro mutants of newly emerged SARS-CoV-2 variants.

2 Dec 2021

Researchers report antibody cocktails are promising candidate tools for controlling new SARS-CoV-2 variants

Researchers from Academia Sinica in Taiwan have been investigating new antibodies that could have strong effects against SARS-CoV-2 infection.

2 Dec 2021

Natural triterpenoids in licorice found to inhibit SARS-CoV-2

In new studies, researchers concluded that licorice triterpenoids could be candidates for anti-SARS-CoV-2 drug developments.

2 Dec 2021

Freeze-dried liposomes could be used in potential COVID-19 vaccines

Things that are freeze-dried: Astronaut food. Emergency rations. And, just maybe, some future COVID-19 vaccines.

1 Dec 2021

Protein found in rattlesnake venom used for making a drug candidate to modulate blood clotting

Researchers in Brazil and Belgium have developed a molecule of pharmaceutical interest from collinein-1, a protein found in rattlesnake venom.

1 Dec 2021

Novel set of immune cells may have the opposite effect in multiple sclerosis, other brain conditions

A group of immune cells that normally protect against inflammation in the gastrointestinal tract may have the opposite effect in multiple sclerosis (MS) and other brain inflammation-related conditions, according to a new study by Weill Cornell Medicine and NewYork-Presbyterian researchers.

1 Dec 2021

Impact of engineered ACE2-Fc on SARS-CoV-2 infection

Researchers employ a structure-guided approach for the development of a series of ACE2-Fc variants using human IgG1 or IgG3 backbone.

1 Dec 2021

Protein C News and Research

Quantum mechanical model offers insights into SARS-CoV-2 evolution

Characterization of two novel SARS-CoV-2 delta variant sublineages

Novel peptide-antibody fusion molecule enhances SARS-CoV-2 variant neutralization

Maternal anemia during pregnancy may increase risk of childhood anemia

Cedars-Sinai researchers uncover the cause of UTI-induced delirium

Link between tobacco product use and alcohol consumption with anti-SARS-CoV-2 antibody titers after BNT162b2 vaccine

Study documents and visualizes hearing loss-associated genes in the inner ear

Non-coding RNA plays a key role in regulating behavior of chromosome loops and gene expression

Men with inherited gene mutation have high risk of aggressive prostate cancer

Genetic variant found in Old Order Amish may confer protective effects against cardiovascular disease

New bioinformatics method for viral sgRNA analysis

Large study of plasma proteome unravels its genetic determinants and relationship with human disease

Systematic survey of human SARS-CoV-2 monoclonal antibodies

Study suggests efficacy of SARS-CoV-2 main protease inhibitors is not compromised in current COVID-19 variants

Researchers report antibody cocktails are promising candidate tools for controlling new SARS-CoV-2 variants

Natural triterpenoids in licorice found to inhibit SARS-CoV-2

Freeze-dried liposomes could be used in potential COVID-19 vaccines

Protein found in rattlesnake venom used for making a drug candidate to modulate blood clotting

Novel set of immune cells may have the opposite effect in multiple sclerosis, other brain conditions

Impact of engineered ACE2-Fc on SARS-CoV-2 infection

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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