Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

FDA approves AChEI ALPHA-1062 for Alzheimer’s disease treatment

On July 29, 2024, the U.S. FDA approved Alpha Cognition Inc.'s ALPHA-1062 (Zunveyl®), an Acetylcholinesterase (AChE) inhibitor, for treating mild-to-moderate Alzheimer’s disease.

From Sino Biological Inc. 5 Aug 2024

Cholesterol imbalance linked to neurodegeneration, study suggests potential strategies for intervention

Research highlights how cholesterol imbalances in the brain contribute to neurodegenerative diseases like Alzheimer's, Huntington's, and Parkinson's, suggesting targeted therapeutic interventions.

5 Aug 2024

New lab technique captures aging effects in Alzheimer's disease development

Researchers at Washington University School of Medicine in St. Louis have developed a way to capture the effects of aging in the development of Alzheimer's disease.

1 Aug 2024

Fish oil may benefit older adults with genetic Alzheimer's risk

A clinical trial at Oregon Health & Science University suggests that a subset of older adults with a genetic predisposition to Alzheimer's disease may benefit from fish oil supplements.

1 Aug 2024

Targeting 14 modifiable risk factors from childhood to old age could prevent or delay dementia

Addressing 14 modifiable risk factors, starting in childhood and continuing throughout life, could prevent or delay nearly half of dementia cases, even as people around the world live longer and the number of people with dementia is set to rise dramatically in all countries, according to the third Lancet Commission on dementia prevention, intervention, and care, which is being presented at the Alzheimer's Association International Conference (AAIC 2024).

1 Aug 2024

Anticancer drugs show promise in reducing Alzheimer's dementia risk

Study finds anticancer drugs, specifically antimetabolites and molecular targeted therapies, may reduce the risk of Alzheimer's type dementia but not vascular dementia.

1 Aug 2024

Exosome-encapsulated fluorescent sensors enable advanced brain imaging in Alzheimer's research

Neurotransmitter levels in the brain can indicate brain health and neurodegenerative diseases like Alzheimer's.

31 Jul 2024

2024 is shaping up to be “the year of iPSCs"

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From Axol Bioscience Ltd 31 Jul 2024

Neurofilament light chain identified as early marker for Parkinson’s and dementia with Lewy Bodies

Early detection of Alzheimer's disease-related changes in Parkinson's disease and dementia with Lewy bodies could be made possible by monitoring the amyloid-β (Aβ) and phosphorylated tau (p-tau) proteins.

31 Jul 2024

High-resolution brain maps reveal vascular blueprint for healthy aging

Healthy blood vessels matter for more than just heart health. Vascular well-being is critical for brain health and potentially in addressing age-related cognitive decline and neurodegenerative disorders, like Alzheimer's disease, according to new study led by Penn State researchers. The findings point to an understudied but possible key role the brain's vascular network - or energy infrastructure - plays in the onset of neurodegenerative disease.

31 Jul 2024

Head-to-head comparison of commercial Alzheimer's blood tests reveals most accurate options

Neurologists diagnose cognitive impairment with a clinical exam of memory and thinking skills.

30 Jul 2024

Spatial patterns of cortical microstructural change can be early indicators of Alzheimer's disease risk

Findings from a novel study in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, published by Elsevier, suggest that using a specialized diffusion weighted MRI scan to monitor the spatial pattern of individual cortical microstructural change in the brain may be a promising approach to characterize individuals who may be vulnerable to developing Alzheimer's disease (AD) prior to significant cognitive decline and irreversible neuronal damage.

30 Jul 2024

Study finds plasma biomarkers can predict dementia risk

A study in JAMA explores the potential of plasma biomarkers for Alzheimer’s disease and cardiometabolic risk factors to predict other types of dementia, highlighting the importance of early diagnosis and combining biomarkers with demographic data for improved accuracy.

30 Jul 2024

Dementia risk rises with elevated remnant cholesterol, South Korean study reveals

How remnant cholesterol (remnant-C) levels are associated with the risk of developing dementia using a large dataset from South Korea.

30 Jul 2024

New blood test achieves 90% accuracy in diagnosing Alzheimer’s disease, outperforms doctors

Researchers in Sweden developed a combined blood test with up to 90% accuracy for diagnosing Alzheimer's disease, surpassing the diagnostic rates of primary care doctors and specialists.

29 Jul 2024

New review highlights advances in diabetes research and treatment

A new paper surveying advances in diabetes pathogenesis and treatment explores the complex factors contributing to the onset and progression of the disease, suggesting that an understanding of these dynamics is key to developing targeted interventions to reduce the risk of developing diabetes and managing its complications.

25 Jul 2024

New brain atlas reveals hidden cell vulnerabilities in Alzheimer's

Researchers created a detailed transcriptomic atlas of six brain regions, revealing cell-type-specific and region-specific vulnerabilities in Alzheimer's disease and highlighting astrocyte genes linked to cognitive resilience.

25 Jul 2024

Experimental cancer drug could make thinking easier for individuals with Rett syndrome

An experimental cancer drug could make thinking easier for individuals with Rett syndrome, a rare disorder linked to autism, according to new research from the University of California San Diego - a discovery that could lead to therapies for patients with other neurological conditions.

25 Jul 2024

Finnish research reveals higher incidence of early-onset dementia among working-age adults

A new major study by the University of Eastern Finland, the University of Oulu and Neurocenter Finland explored early-onset dementia in the working-age population in Finland.

25 Jul 2024

Unprecedented brain cell mapping sheds light on Alzheimer's

Less than a decade ago, when Dr. Hansruedi Mathys launched an ambitious project to create an annotated library of all the gene readouts stored within 100 individual brain cells, the task felt daunting.

25 Jul 2024

Alzheimer's Disease News and Research

Further Reading

FDA approves AChEI ALPHA-1062 for Alzheimer’s disease treatment

Cholesterol imbalance linked to neurodegeneration, study suggests potential strategies for intervention

New lab technique captures aging effects in Alzheimer's disease development

Fish oil may benefit older adults with genetic Alzheimer's risk

Targeting 14 modifiable risk factors from childhood to old age could prevent or delay dementia

Anticancer drugs show promise in reducing Alzheimer's dementia risk

Exosome-encapsulated fluorescent sensors enable advanced brain imaging in Alzheimer's research

2024 is shaping up to be “the year of iPSCs"

Neurofilament light chain identified as early marker for Parkinson’s and dementia with Lewy Bodies

High-resolution brain maps reveal vascular blueprint for healthy aging

Head-to-head comparison of commercial Alzheimer's blood tests reveals most accurate options

Spatial patterns of cortical microstructural change can be early indicators of Alzheimer's disease risk

Study finds plasma biomarkers can predict dementia risk

Dementia risk rises with elevated remnant cholesterol, South Korean study reveals

New blood test achieves 90% accuracy in diagnosing Alzheimer’s disease, outperforms doctors

New review highlights advances in diabetes research and treatment

New brain atlas reveals hidden cell vulnerabilities in Alzheimer's

Experimental cancer drug could make thinking easier for individuals with Rett syndrome

Finnish research reveals higher incidence of early-onset dementia among working-age adults

Unprecedented brain cell mapping sheds light on Alzheimer's

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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