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Study shows red wine biomarkers in urine can predict inflammation levels

Researchers found that specific metabolites of resveratrol in urine accurately reflect red wine consumption. These biomarkers were linked to reduced inflammation in older adults at cardiovascular risk, unlike traditional food surveys.

25 Mar 2025

Study reveals distinct infection strategies of Zika and dengue viruses

Zika virus and dengue virus are very close relatives. Both are mosquito-borne flaviviruses, and both specialize in infecting a host's dendritic cells.

25 Mar 2025

Stanford study reveals glucose's surprising role in cell differentiation

The sugar glucose, which is the main source of energy in almost every living cell, has been revealed in a Stanford Medicine study to also be a master regulator of tissue differentiation - the process by which stem cells give rise to specialized cells that make up all the body's tissues.

25 Mar 2025

Breakthrough DNA delivery system could revolutionize chronic disease treatment

A breakthrough in safely delivering therapeutic DNA to cells could transform treatment for millions suffering from common chronic diseases like heart disease, diabetes, and cancer.

25 Mar 2025

New brain metabolism model reveals key targets for reversing aging

The most comprehensive model of the brain’s metabolism, incorporating more than 16,800 biochemical interactions, has identified key targets to reverse the age-related decline in brain function.

25 Mar 2025

Ancient appetite-control molecule found in starfish and humans

A team of biologists at Queen Mary University of London has discovered that a neurohormone controlling appetite in humans has an ancient evolutionary origin, dating back over half a billion years.

24 Mar 2025

New MIT method promises less painful drug injections with tiny crystals

MIT engineers have devised a new way to deliver certain drugs in higher doses with less pain, by injecting them as a suspension of tiny crystals.

24 Mar 2025

Simple urine test may spare kidney cancer patients from invasive scans

A simple urine test could accurately show the recurrence of kidney cancer at an early stage, potentially sparing patients invasive scans and enabling faster access to treatment, new research has shown.

24 Mar 2025

Researchers develop tool to enhance NK cells against cancer

A team of researchers from the Hospital del Mar Research Institute, the Universitat Autònoma de Barcelona and the Pompeu Fabra University has developed a new tool that allows modifying these NK cells to make them immune to the tumor’s defense mechanism.

24 Mar 2025

New light-driven process could accelerate the discovery of new drugs

Researchers at Indiana University and Wuhan University in China have unveiled a groundbreaking chemical process that could streamline the development of pharmaceutical compounds, chemical building blocks that influence how drugs interact with the body.

22 Mar 2025

Innovative photoacoustic sensing could replace needle-based glucose testing

Blood glucose is usually measured using invasive methods involving pricking small needles into the skin.

21 Mar 2025

Eye drops show potential to slow progression of human degenerative retinal diseases

Treatment shows potential to slow the progression of human degenerative eye diseases, including retinitis pigmentosa.

21 Mar 2025

Natural compounds identified as potential inhibitors of SARS-CoV-2 spike protein

The COVID-19 pandemic highlighted the urgent need for effective therapeutic agents against SARS-CoV-2.

20 Mar 2025

New function of Exportin-1 discovered in gene transcription

Researchers from Northwestern University have stumbled upon a previously unobserved function of a protein found in the cell nuclei of all flora and fauna.

20 Mar 2025

New targeted therapy shows early success in treating pediatric high-grade gliomas

An international team of clinical collaborators, led by physician scientists from Dana-Farber Cancer Institute, performed a first-ever clinical test of the targeted therapy avapritinib in pediatric and young patients with a form of high-grade glioma.

20 Mar 2025

Scientists discover irreversible peptide inhibitors for undruggable cancer target

For the first time scientists have identified promising drug candidates that bind irreversibly with a notoriously "undruggable" cancer protein target, permanently blocking it.

20 Mar 2025

Targeted inhibition of a 'signal jammer' protein may improve tumor response to immunotherapy

Targeted inhibition of a "signal jammer" protein may improve how tumors respond to immunotherapy. Published today in Nature, a new study demonstrates how some cancer cells use the protein voltage-dependent anion channel 2 (VDAC2) like a signal jammer to prevent the body's anticancer systems from communicating with the immune system.

19 Mar 2025

Breakthrough study unveils mechanics of DNA unwinding

For the first time, scientists have witnessed the very moment DNA begins to unravel, revealing a necessary molecular event for DNA to be the molecule that codes all life.

19 Mar 2025

Most in-depth simulation of brain metabolism yet reveals new targets for future dementia treatments

The findings come from the most comprehensive computer model of brain metabolism to date, which incorporates more than 16,800 biochemical interactions between proteins and chemicals across brain cells, supporting cells, and the blood.

19 Mar 2025

Understanding the role of CD2AP in Alzheimer's disease

A groundbreaking peer-reviewed Thought Leaders Invited Review article in Brain Medicine (Genomic Press, New York) explores how CD2-associated protein (CD2AP) contributes to Alzheimer's disease (AD), one of the most devastating neurodegenerative disorders affecting millions worldwide.

19 Mar 2025