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Opioid-sparing anesthesia reduces opioid-related adverse events in cardiac surgery

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Mounting evidence indicates that opioid-sparing anesthesia (OSA) decreases opioid-related adverse events. This article examines whether OSA might improve initial recovery after cardiac surgery.

24 Feb 2025

Interferon gamma persistence offers clues to Long COVID and potential therapies

SARS-CoV-2 triggers the production of the antiviral protein IFN-γ, which is associated with fatigue, muscle ache and depression. New research shows that in Long COVID patients, IFN-y production persists until symptoms improve, highlighting a potential biomarker and a target for therapies.

22 Feb 2025

Characterizing the spectrum of mitochondrial DNA deletion disease syndromes

Researchers from the Mitochondrial Medicine Program at Children's Hospital of Philadelphia (CHOP) have better characterized a spectrum of what were classically considered discrete mitochondrial DNA deletion disease syndromes.

21 Feb 2025

New guidelines allow select athletes with heart abnormalities to participate in competitive sports

Recent research suggests that select athletes with cardiovascular abnormalities may be able to safely participate in competitive sports after shared decision-making with their clinicians about potential risks, according to a joint scientific statement published today in the American Heart Association's flagship, peer-reviewed journal Circulation and simultaneously in JACC, the flagship journal of the American College of Cardiology.

21 Feb 2025

CBD boosts endurance in mice by reshaping gut bacteria and enhancing muscle performance

Study shows that cannabidiol (CBD) enhances endurance exercise in mice by reshaping gut microbiota, boosting mitochondrial function, and altering muscle fiber composition for improved performance.

20 Feb 2025

Long-term grape consumption shown to improve muscle health in both men and women

A new study from Western New England University (WNE) has revealed that long-term grape consumption significantly impacts muscle health, with notable benefits for both men and women.

20 Feb 2025

First prenatal treatment for spinal muscular atrophy shows promising results

Spinal muscular atrophy (SMA) is a progressive neurodegenerative disorder set in motion before birth. Scientists at St. Jude Children's Research Hospital led the first in uterotreatment of SMA with the orally administered drug risdiplam.

20 Feb 2025

Breakthrough in gene therapy could help protect against heart arrhythmias

Cardiac arrhythmias affect millions across the world and are responsible for a fifth of all deaths in the Netherlands.

20 Feb 2025

Study uncovers molecular mechanisms behind insulin resistance in skeletal muscle

Insulin resistance precedes and predicts the onset of type 2 diabetes mellitus (DM2), a chronic disease that causes high morbidity and mortality worldwide.

19 Feb 2025

Common antidepressant Fluoxetine protects from sepsis-induced death

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19 Feb 2025

Radiation and immunotherapy help preserve bladders in patients with muscle-invasive bladder cancer

Patients with localized muscle-invasive bladder cancer (MIBC) who received radiation plus the immune checkpoint inhibitors (ICIs) durvalumab (Imfinzi) and tremelimumab (Imjudo) had durable responses that allowed for bladder preservation, according to results from the IMMUNOPRESERVE clinical trial.

18 Feb 2025

New drug mimics low-oxygen treatment for Leigh Syndrome

For the average person, living at high altitude-where oxygen is sparser than at sea level-can have health benefits ranging from lower rates of heart disease to increased endurance.

18 Feb 2025

First insights into familial ALS in Egypt reveal genetic variations and disease progression

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease characterized by the progressive degeneration of motor neurons, leading to muscle weakness and eventually death.

18 Feb 2025

Scientists pinpoint metabolic failure as the cause of muscle loss in aging

A multi-omics study reveals that impaired branched-chain amino acid (BCAA) catabolism is a key driver of sarcopenia, suggesting it as a potential therapeutic target.

17 Feb 2025

Do probiotics enhance sports performance?

Researchers found that probiotics may enhance endurance, recovery, and immune function in athletes, but the evidence for strength and power performance remains limited.

17 Feb 2025

Rare enterovirus strain in Spain raises alarms over potential outbreaks

Scientists in Spain detected Enterovirus C105 (EV-C105), a rare virus linked to respiratory and possible neurological illness in children, highlighting the emergence of a genetically distinct viral strain.

17 Feb 2025

Innovative photodynamic therapy targets melanoma with light-activated dyes

Melanoma is one of the most aggressive skin cancers, with over 300,000 new cases reported worldwide each year. In Europe, the number of diagnoses has been rising rapidly.

17 Feb 2025

Researchers develop a way to treat muscular atrophy using regenerative medicine

Researchers from Tokyo Metropolitan University have developed a way to treat ageing-related muscular atrophy using regenerative medicine.

17 Feb 2025

Sweet taste receptors found in the heart could affect heartbeat

In a surprising discovery, scientists have found that the heart possesses "sweet taste" receptors, similar to those on our tongues, and that stimulating these receptors with sweet substances can modulate the heartbeat.

17 Feb 2025

Obesity and cognition: Surprising study links higher BMI to better memory

Higher BMI in early adulthood and midlife is linked to better memory performance, particularly in men and Black Americans, challenging traditional views on obesity and cognition.

16 Feb 2025