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Cellular "barcoding" in mice unravels the origins of blood

The origins of our blood may not be quite what we thought. Using cellular "barcoding" in mice, a groundbreaking study finds that blood cells originate not from one type of mother cell, but two, with potential implications for blood cancers, bone marrow transplant, and immunology. Fernando Camargo, PhD, of the Stem Cell Program at Boston Children's Hospital led the study, published in Nature on June 15.

15 Jun 2022

Study: Uterine transplantation is an effective, safe method to remedy infertility

Transplanting a uterus is an effective, safe method to remedy infertility when a functioning uterus is lacking.

14 Jun 2022

Increasing growth hormone levels can improve liver health in patients with NAFLD

Growth hormone improves liver health in patients with nonalcoholic fatty liver disease (NAFLD) by reducing liver fat and inflammation, according to a new study presented Tuesday, June 14 at ENDO 2022, the Endocrine Society's annual meeting in Atlanta, Ga.

14 Jun 2022

Duke Children's Hospital & Health Center retains No. 1 rank in North Carolina

Duke Children's Hospital & Health Center continues to rank as the No. 1 children's hospital in North Carolina by U.S. News & World Report, with nine pediatric specialties ranked among the best in the nation.

14 Jun 2022

RNA exosomes play a key role in B cell development, UTSW study suggests

New research from UT Southwestern suggests that RNA exosomes – the cellular machines that degrade old molecules of RNA – play a key role in the development of B cells, which are critical to the immune system's ability to protect against infection.

13 Jun 2022

Race is often used as medical shorthand for how bodies work. Some doctors want to change that.

Several months ago, a lab technologist at Barnes-Jewish Hospital mixed the blood components of two people: Alphonso Harried, who needed a kidney, and Pat Holterman-Hommes, who hoped to give him one.

13 Jun 2022

Scientists find new link between high-fat, high-fructose diets and Type 2 diabetes mellitus

Those who are habitually inclined to consume burgers, fries and soda may think twice about their dietary choices following scientists' latest findings about high-fat, high-fructose diets.

10 Jun 2022

COVID-19 vaccination associated with reduction in hospitalizations and mortality among heart failure patients

Heart failure patients who are unvaccinated against SARS-CoV-2, the virus that causes COVID-19, are three times more likely to die if infected with the virus compared to fully boosted heart failure patients, according to new research out of Mount Sinai Heart.

9 Jun 2022

Zinc may reverse lung damage, improve survival for patients with idiopathic pulmonary fibrosis

Investigators from the Women's Guild Lung Institute at Cedars-Sinai have discovered that zinc, a common mineral, may reverse lung damage and improve survival for patients with a deadly age-related condition known as idiopathic pulmonary fibrosis (IPF).

8 Jun 2022

Oral administration of rapamycin increases β-amyloid buildup in Alzheimer's disease mouse model

Researchers from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) have found that oral administration of rapamycin to an Alzheimer's disease mouse model causes an increase in beta (β)-amyloid protein plaques. β-amyloid buildup is a hallmark of Alzheimer's disease.

7 Jun 2022

Three-drug therapy with autologous stem cell transplant improves progression-free survival for multiple myeloma patients

Patients with multiple myeloma who have been treated with a three-drug combination therapy have a growing number of choices for subsequent treatment. Results of a new study led by researchers at Dana-Farber Cancer Institute can help patients and their physicians weigh benefits and risks of each option.

6 Jun 2022

Study confirms the benefits of 'bridge therapy' for some children with high-risk neuroblastoma

Approximately half of children with neuroblastoma - a childhood cancer that develops from immature nerve cells - have a form that indicates a high likelihood of recurrence.

6 Jun 2022

Weight loss with bariatric surgery associated with lower risk of cancer and cancer-related mortality

A Cleveland Clinic study shows that among adults with obesity, weight loss achieved with bariatric surgery was associated with a 32% lower risk of developing cancer and a 48% lower risk of cancer-related death compared with adults who did not have the surgery.

3 Jun 2022

Vaccination lowers the risk of experiencing severe COVID-19 in dialysis patients

In an analysis of patients with kidney failure receiving dialysis who had become infected with SARS-CoV-2, those who were vaccinated had a lower risk of experiencing severe COVID-19.

3 Jun 2022

New research may open a window to treating aggressive form of B-cell acute lymphoblastic leukemia

Survival has improved greatly in children with acute lymphocytic leukemia (ALL). But a certain form of ALL that occurs mostly in babies is still very lethal, with a survival rate below 50 percent: B-cell acute lymphoblastic leukemia with rearrangements of the mixed lineage leukemia gene, or MLL B-ALL.

1 Jun 2022

Taco bowls and chicken curry: Medi-Cal delivers ready meals in grand health care experiment

The effectiveness of sotrovimab vs. molnupiravir in preventing severe COVID-19 outcomes in non-hospitalized high-risk COVID-19 adult patients

Researchers compared the efficacy of sotrovimab and molnupiravir in preventing severe COVID-19 outcomes among non-hospitalized and high-risk COVID-19 patients across England.

25 May 2022

Transplant News and Research

Cellular "barcoding" in mice unravels the origins of blood

Study: Uterine transplantation is an effective, safe method to remedy infertility

Increasing growth hormone levels can improve liver health in patients with NAFLD

Duke Children's Hospital & Health Center retains No. 1 rank in North Carolina

RNA exosomes play a key role in B cell development, UTSW study suggests

Race is often used as medical shorthand for how bodies work. Some doctors want to change that.

Scientists find new link between high-fat, high-fructose diets and Type 2 diabetes mellitus

COVID-19 vaccination associated with reduction in hospitalizations and mortality among heart failure patients

Zinc may reverse lung damage, improve survival for patients with idiopathic pulmonary fibrosis

Oral administration of rapamycin increases β-amyloid buildup in Alzheimer's disease mouse model

Three-drug therapy with autologous stem cell transplant improves progression-free survival for multiple myeloma patients

Study confirms the benefits of 'bridge therapy' for some children with high-risk neuroblastoma

Weight loss with bariatric surgery associated with lower risk of cancer and cancer-related mortality

Vaccination lowers the risk of experiencing severe COVID-19 in dialysis patients

New research may open a window to treating aggressive form of B-cell acute lymphoblastic leukemia

Taco bowls and chicken curry: Medi-Cal delivers ready meals in grand health care experiment

Evaluating tixagevimab plus cilgavimab against SARS-CoV-2

New virtual biopsy could lead to major improvements in care for heart transplant patients

Aston University’s new antibiotic combination forms part of a lifesaving treatment for cystic fibrosis

The effectiveness of sotrovimab vs. molnupiravir in preventing severe COVID-19 outcomes in non-hospitalized high-risk COVID-19 adult patients

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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