Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Association between SARS-CoV-2 Omicron viral load and vaccination history

Researchers analyzed the association between viral loads in SARS-CoV-2 Omicron variant infection and vaccination history.

21 Apr 2022

Evolution of SARS-CoV-2 variants

Research has demonstrated the evolutionary process and biology of SARS-CoV-2, the causative pathogen of the COVID-19 pandemic.

21 Apr 2022

RNA splicing abnormalities in COVID-19 patients

This study entailed the integration of multiple-omics datasets to examine the dysregulation in the host splicing mechanism and alteration in protein isoforms among COVID-19 patients.

20 Apr 2022

New insight into SARS-CoV-2 main protease opens door to new viral inhibitors

A recent study has revealed a full cycle of substrate cleavage for the main protease of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – providing, in turn, a steadfast foundation for developing potent new viral inhibitors. The paper was published in the journal Proceedings of the National Academy of Sciences (PNAS).

20 Apr 2022

CryoEM reveals never-before-seen details of the human androgen receptor

Scientists at Memorial Sloan Kettering Cancer Center (MSK) have glimpsed never-before-seen details of the human androgen receptor - the protein inside of cells that responds to male-typical hormones like testosterone.

20 Apr 2022

Antibody response to Pfizer-BioNTech COVID-19 vaccine over 6 months

A new study published in PLoS ONE characterizes the antibody response to BNT162b2, the Pfizer-BioNTech COVID-19 vaccine

20 Apr 2022

Novel saliva immunoassays to detect prior SARS-CoV-2 infection

Six salivary ELISAs were developed to evaluate the immune response to SARS-CoV-2 and estimate rates of past infection.

20 Apr 2022

Scientists demonstrate a new mechanism by which amino acids curb appetite

Proteins can suppress appetite, so a protein-rich diet can help people lose weight. That's just one of the reasons why this kind of diet has become increasingly popular in recent years.

20 Apr 2022

New technology enables single-cell sorting based on functional outputs

For nearly 40 years, drugmakers have used genetically engineered cells as tiny drug factories. Such cells can be programmed to secrete compounds that yield drugs used to treat cancer and autoimmune conditions such as arthritis.

20 Apr 2022

Acquiring real-time, accurate and reproducible 4D bioinformatics data with PaSER

In this interview, Chris Adams Ph.D., Business Development Director, Global Bioinformatics, Life Science Mass Spectrometry at Bruker Daltonics, Billerica, MA, USA talks to News-Medical Life Sciences about acquiring real-time, accurate and reproducible 4D-proteomics data with PaSER.

From Bruker Daltonics 20 Apr 2022

Investigating the impact of SARS-CoV-2 Omicron spike mutations

Researchers investigated the impact of amino acid substitutions of SARS-CoV-2 Omicron on spike protein function, processing, and neutralization susceptibility.

20 Apr 2022

Polyethylene glycol-specific antibody responses induced by mRNA-1273 COVID-19 vaccine

Researchers determined the impact of COVID-19 vaccines on polyethylene glycol-specific antibody responses.

20 Apr 2022

Study investigates co-metabolism during SARS-CoV-2 infection

In a new study, researchers investigated host-virus co-metabolism during a SARS-CoV-2 infection.

20 Apr 2022

Waning antibody responses in SARS-CoV-2-infected children and adults over time

In a new study, researchers evaluated the duration of antibodies against SARS-CoV-2.

20 Apr 2022

Study explores SARS-CoV-2 Omicron variant and infected colon epithelial cells

In a new study, researchers assessed the impact of the SARS-CoV-2 Omicron variant on infected human cells and organs.

20 Apr 2022

Study demonstrates subset of vaccine-induced HLA-A*24:02-restricted T cells exhibits enhanced reactivity against the Omicron BA.1 variant

Researchers characterized vaccine-induced T cell response specific for spike proteins of several SARS-CoV-2 variants.

20 Apr 2022

Persistent loss of smell after COVID-19 associated with altered olfactory epithelial gene expression

Researchers performed histology of the olfactory epithelium for smell loss measurements in patients with post-acute sequelae of SARS-CoV-2 infection.

20 Apr 2022

Study evaluates the ocular tropism and the possible ocular transmission of SARS-CoV-2 in animal models

Researchers demonstrated ocular tropism of SARS-CoV-2 through neuronal invasion in transgenic mice with hACE2 expression.

20 Apr 2022

Study reveals a complexity to how the body "regulates the regulators" of the immune system

Checkpoint inhibitors have become important tools in the cancer-fighting arsenal. By blocking proteins that normally restrain the immune response, these drugs can help the immune system destroy cancer cells.

20 Apr 2022

Little-known protein found to play a role in common neurodegenerative disorder

Scientists have known for years that amyloid fibrils - fibrous, ropelike structures formed by closely linked protein molecules - are present in the brains of patients with Alzheimer's and Parkinson's diseases and likely play a role in the progression of these disorders.

20 Apr 2022