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Researchers recommend antibody cocktail to tackle SARS-CoV-2 mutations

A new study released on the medRxiv* preprint server indicates that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent responsible for the current coronavirus disease 2019 (COVID-19) pandemic – is developing multiple mutations that affect neutralization by antibodies.

24 Nov 2020

Biosensor assay SARS-CoV-2 antibody test may predict COVID-19 severity in patients

Researchers in New York, USA, have found an association of mortality with an early humoral response to SARS-CoV-2 infection within the first few days after onset of symptoms (DAOS), using a highly sensitive and automated testing-on-a-probe (TOP) biosensor assays for SARS-CoV-2.

24 Nov 2020

Researchers develop new scoring system to screen for dual heart disease

Aortic stenosis is one of the most common heart valve defects. Its prevalence increases with age and it often requires treatment.

24 Nov 2020

Research links SARS-CoV-2 prevalence, hospital surfaces and patient microbiomes

Researchers found a higher bacterial diversity in SARS-CoV-2 patient rooms and surfaces in the room, suggesting bacterial diversity may play a role in virus transmission.

24 Nov 2020

Study sheds new light on impact of COVID-19 in pediatric population

In the most comprehensive analysis to date of U.S. children tested and treated for COVID-19, an organization representing seven of the nation's largest pediatric medical centers reports that some groups of children are faring significantly worse than children in general during the pandemic.

24 Nov 2020

SARS-CoV-2 RNA best preserved in wastewater under freezing conditions

Wastewater surveillance has been reported to be a feasible and efficient way to monitor the prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the current COVID-19 pandemic. A recent study draws attention to the need to freeze wastewater samples if the analysis is carried out later rather than immediately.

24 Nov 2020

COVID-19: HLA class I genotypes and mortality

The study, published on the preprint server medRxiv, explores the ability of HLA class I molecules to mediate the outcome in COVID-19 patients.

24 Nov 2020

Study shows BICRA gene functions in neural development in humans, flies

Physicians and scientists are constantly on the lookout for new disease genes that can help them understand why patients have undiagnosed medical problems.

23 Nov 2020

Favorable clinical outcome for ivermectin in COVID-19 animal model

A team of researchers at the Institut Pasteur in France has found that ivermectin prevented clinical deterioration in infected animals. The drug also reduced the inflammatory cytokines, interleukin-6 and 10 (IL-6 and IL-10) in lung tissue, which leads to more favorable clinical outcomes in treated animals.

23 Nov 2020

Scientists studying aerodynamics of infectious disease reveal ways to reduce indoor SARS-CoV-2 transmission

At the 73rd Annual Meeting of the American Physical Society's Division of the Americal Physical Society's Division of Fluid Dynamics, researchers presented a range of studies investigating the aerodynamics of infectious disease.

23 Nov 2020

Septic shock and pneumonia triggered by SARS-CoV-2 could be treated by radiation-activated MSCs

This study, published in the journal Cells, is based on others (all of which employed experimental models) previously conducted by researchers at the Biomedical Research Centre of the University of Granada, the ‘López-Neyra’ Institute of Parasitology and Biomedicine, and the ‘Virgen de las Nieves’ University Hospital in Granada

23 Nov 2020

New CDC report describes COVID-19 in NYC in early spring

The Centres for Disease Control and Prevention (CDC), in its Morbidity and Mortality Weekly Report (MMWR), has published an update on the outbreak in New York City. The report is titled, "COVID-19 Outbreak — New York City, February 29–June 1, 2020".

23 Nov 2020

Mildly symptomatic COVID-19 patients may be contagious for longer than previously thought

Researchers in Brazil have reported two cases of people with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) shedding infectious virus for a significantly longer period than has previously been reported.

23 Nov 2020

Repeat infection following COVID-19 recovery may not pose risk to close contacts

Researchers in China have conducted a study suggesting that people who have recovered from coronavirus disease 2019 (COVID-19) may not pose a risk to close contacts if they become reinfected with the causative agent severe acute respiratory syndrome coronavirus (SARS-CoV-2).

23 Nov 2020

SARS-CoV-2's spike protein mutations have slowed, study finds

A team of researchers at the School of Information Sciences in Illinois, USA, has revealed the rate of mutation in the 29 proteins that make up the SARS-CoV-2 microbe.

23 Nov 2020

How COVID-19 compares to other respiratory illnesses

A team of scientists from Israel and the United States has compared the disease presentation and progression between in-hospital patients with coronavirus disease 2019 (COVID-19) and other respiratory illnesses such as influenza.

23 Nov 2020

SARS-CoV-2 spike deletion mutations may evade current vaccine candidates, study finds

A thought-provoking new study reports that the anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike antibodies elicited by natural infection may not be able to neutralize emerging strains that display deletion mutations in their genomic RNA.

23 Nov 2020

Scientists make breakthrough in studying the enzyme involved in fish odor syndrome

Fish odor syndrome (trimethylaminuria) is a debilitating disease, in which the liver cannot break down the smelly chemical trimethylamine which is produced by enzymes from bacteria residing in the gut leaving people with a fish like odor.

23 Nov 2020

Nasal dryness could be an early warning sign of COVID-19

A new study published by an international team of researchers on the preprint medRxiv* server in November 2020 details the nasal symptoms that are associated with anosmia and ageusia (loss of smell and taste) in coronavirus disease 2019 (COVID-19), including the early warning signs of infection.

23 Nov 2020

Modified SARS-CoV-2 receptor-binding domain could increase vaccine efficacy, says study

A team of researchers from the USA and China have engineered a receptor-binding domain (RBD) that they claim improves the immunogenicity of multivalent SARS-CoV-2 vaccines. Their study, which was released on the bioRxiv* in November 2020, may help advance even more efficacious SARS-CoV-2 vaccine candidates in the future.

23 Nov 2020

Syndrome News and Research

Researchers recommend antibody cocktail to tackle SARS-CoV-2 mutations

Biosensor assay SARS-CoV-2 antibody test may predict COVID-19 severity in patients

Researchers develop new scoring system to screen for dual heart disease

Research links SARS-CoV-2 prevalence, hospital surfaces and patient microbiomes

Study sheds new light on impact of COVID-19 in pediatric population

SARS-CoV-2 RNA best preserved in wastewater under freezing conditions

COVID-19: HLA class I genotypes and mortality

Study shows BICRA gene functions in neural development in humans, flies

Favorable clinical outcome for ivermectin in COVID-19 animal model

Scientists studying aerodynamics of infectious disease reveal ways to reduce indoor SARS-CoV-2 transmission

Septic shock and pneumonia triggered by SARS-CoV-2 could be treated by radiation-activated MSCs

New CDC report describes COVID-19 in NYC in early spring

Mildly symptomatic COVID-19 patients may be contagious for longer than previously thought

Repeat infection following COVID-19 recovery may not pose risk to close contacts

SARS-CoV-2's spike protein mutations have slowed, study finds

How COVID-19 compares to other respiratory illnesses

SARS-CoV-2 spike deletion mutations may evade current vaccine candidates, study finds

Scientists make breakthrough in studying the enzyme involved in fish odor syndrome

Nasal dryness could be an early warning sign of COVID-19

Modified SARS-CoV-2 receptor-binding domain could increase vaccine efficacy, says study

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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