Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

New clues about how brain cells are damaged by Alzheimer's disease

University of Kentucky chemistry professor Allan Butterfield has uncovered new clues about how brain cells are damaged by Alzheimer's disease, evidence suggesting vitamin E may help prevent the debilitating illness.

1 Nov 2004

Warning on Alzheimer drug mix up

Janssen Pharmaceutica, manufacturer of the Alzheimer drug galantamine (Reminyl), says it has learned of 10 cases in which individuals who should have gotten Reminyl accidentally received the diabetes drug glimepiride (Amaryl).

1 Nov 2004

Researchers help define Apolipoprotein E's role in the formation of amyloid brain lesions and the memory loss associated with Alzheimer's disease

A research team led by University of South Florida neuroscientist Huntington Potter, PhD, CEO of the Johnnie B. Byrd Sr. Alzheimer's Center & Research Institute, for the first time has defined how the protein Apolipoprotein E (ApoE) contributes to both the formation of amyloid brain lesions and the memory loss associated with Alzheimer's disease.

1 Nov 2004

Interaction of nervous system proteins help researchers better understand age-related memory and hearing loss

In a finding that may one day help researchers better understand age-related memory and hearing loss, scientists have shown that two key nervous system proteins interact in a manner that helps regulate the transmission of signals in the nervous system.

29 Oct 2004

Trojan horse technique offers potential new therapeutic approach to Alzheimer's disease

A potential new therapeutic approach to Alzheimer's disease protects brain cells in culture by drastically reducing the neurotoxic amyloid protein aggregates that are critical to the development of the disease.

29 Oct 2004

Is NICE delivering the goods?

Implementation of guidance issued by the National Institute for Clinical Excellence (NICE) has been mixed, according to a study in this week's BMJ.

29 Oct 2004

Scientists are trying to determine what goes on inside the brain when it sees a face

Ever catch a glimpse of someone but can't quite fit a name to go with the face? While it's something that happens to everyone, for older people especially, difficulty in retrieving names is a common frustration.

28 Oct 2004

New insights into hormone therapy show when estrogen best aids brain

New hormone therapy studies demonstrate estrogen's ability to directly stimulate neurons, repair damaged neurons, and stimulate support cells—most of which can alleviate some of the cognitive decline associated with menopause.

28 Oct 2004

Study suggests safer immunization approach to Alzheimer's

Researchers at the University of Illinois at Chicago have had preliminary success with a method of immunization intended to dissolve the plaques in brain tissue that are associated with Alzheimer's disease.

28 Oct 2004

Scientists closer to understanding the potential effects of anti-cholesterol drugs on Alzheimer's disease

Scientists at Jefferson Medical College and the Farber Institute for Neurosciences at Thomas Jefferson University in Philadelphia have taken another step in understanding the potential effects of anti-cholesterol drugs on Alzheimer's disease.

25 Oct 2004

Fish oil reverses age-related ailments

University of Bradford student Samantha Little has been awarded a Young Investigators Award at an international congress for her work on the effect of fish oil on the ageing brain.

25 Oct 2004

Researchers have identified a protein in the brain that halts the progression of Alzheimer's

Researchers have identified a protein in the brain that halts the progression of Alzheimer's disease in human brain tissue. The protein, known as "transthyretin," protects brain cells from gradual deterioration by blocking another toxic protein that contributes to the disease process.

25 Oct 2004

New oral vaccine treatment is effective in reducing Alzheimer's disease pathology

Alzheimer's disease is characterized by progressive loss of cognitive function due to amyloid-beta (Aß) deposits in the central nervous system. If these deposits could be stopped or slowed, Alzheimer's disease might become more manageable.

25 Oct 2004

Drinking regular cuppas could help improve your memory

Results of laboratory tests by a team from the University of Newcastle upon Tyne found that green and black tea inhibit the activity of certain enzymes in the brain which are associated with memory.

25 Oct 2004

Men undergoing prostate cancer therapy forget things faster

Oregon Health & Science University researchers studying how testosterone deprivation affects verbal memory found that men undergoing the prostate cancer therapy forget things faster than their healthy counterparts.

25 Oct 2004

BMA report hopes to raise awareness about the threat of biological weapons

A new report released today (25 October 2004) by the BMA paints a bleak picture of the global community's ability to cope with advances in biological and genetic weapons technology.

25 Oct 2004

Key discovery toward understanding mechanism associated with uncontrollable muscular movements

Neurodegenerative diseases such as Alzheimer's, Parkinson's, Lou Gehrig's and Huntington's exhibit loss of nerve function in different ways, from memory lapses to uncontrollable muscular movements, but it is now believed that these diseases share many common molecular mechanisms.

22 Oct 2004

Neuroimaging initiative to track early signs of Alzheimer’s disease

Researchers are looking for ways to spot early warning signs in the brain of developing Alzheimer’s disease.

22 Oct 2004

Possible link between elevated calcium levels in older neurons and aging-related disorders of the brain

Brain cells become increasingly unable to regulate calcium loads as they age, becoming more vulnerable to injury and premature death, according to new findings that Virginia Commonwealth University researchers will present at an international conference this month.

20 Oct 2004

Single protein appears central to the formation of the long-term memories

Researchers at the National Institute of Child Health and Human Development have discovered that a single protein appears central to the formation of the long-term memories.

16 Oct 2004

Alzheimer's Disease News and Research

Further Reading

New clues about how brain cells are damaged by Alzheimer's disease

Warning on Alzheimer drug mix up

Researchers help define Apolipoprotein E's role in the formation of amyloid brain lesions and the memory loss associated with Alzheimer's disease

Interaction of nervous system proteins help researchers better understand age-related memory and hearing loss

Trojan horse technique offers potential new therapeutic approach to Alzheimer's disease

Is NICE delivering the goods?

Scientists are trying to determine what goes on inside the brain when it sees a face

New insights into hormone therapy show when estrogen best aids brain

Study suggests safer immunization approach to Alzheimer's

Scientists closer to understanding the potential effects of anti-cholesterol drugs on Alzheimer's disease

Fish oil reverses age-related ailments

Researchers have identified a protein in the brain that halts the progression of Alzheimer's

New oral vaccine treatment is effective in reducing Alzheimer's disease pathology

Drinking regular cuppas could help improve your memory

Men undergoing prostate cancer therapy forget things faster

BMA report hopes to raise awareness about the threat of biological weapons

Key discovery toward understanding mechanism associated with uncontrollable muscular movements

Neuroimaging initiative to track early signs of Alzheimer’s disease

Possible link between elevated calcium levels in older neurons and aging-related disorders of the brain

Single protein appears central to the formation of the long-term memories

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