Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Researchers find mutations in a multifunctional protein cause Parkinsonism

A team of researchers at Mayo Clinic in Jacksonville, Fla. and colleagues in Canada and Germany have discovered a gene and six mutations of it that cause symptoms associated with Parkinson's disease and other neurodegenerative disorders.

18 Nov 2004

Eating apples may protect against Alzheimer's and Parkinsonism

A group of chemicals in apples could protect the brain from the type of damage that triggers such neurodegenerative diseases as Alzheimer's and Parkinsonism, according to two new studies from Cornell University food scientists.

18 Nov 2004

A challenging job protects against the development of dementia

Jobs that are both challenging and afford opportunities to take responsibility seem to protect against the development of dementia, concludes research in Occupational and Environmental Medicine.

17 Nov 2004

Researchers find effective treatment for Unusual Fever Syndrome caused by cold exposure

Remember when Grandma used to say, "don’t go out in the cold; you’ll get sick”? It turns out that she was right for a small number of people who have a condition called familial cold autoinflammatory syndrome (FCAS)

16 Nov 2004

Financial impact of diabetes on the American economy

Sick days, disability, early retirement, and premature death of diabetic Americans born between 1931 and 1941 cost the country almost $133.5 billion by the year 2000, according to a new estimate by researchers with the University of Michigan (U-M) and the Department of Veterans Affairs (VA).

16 Nov 2004

Atorvastatin slows down mental decline and improves depressive symptoms in people with Alzheimer’s disease

The cholesterol-lowering drug atorvastatin slowed down mental decline and improved depressive symptoms in people with Alzheimer’s disease, according to a small pilot study reported at the American Heart Association’s Scientific Sessions 2004.

11 Nov 2004

Dementia patients receiving long-term treatment with Reminyl may be able to stay at home for longer compared

Shire Pharmaceuticals Group has announced that Dementia patients receiving long-term treatment with Reminyl (more than 36 months) may be able to stay at home for longer compared to those receiving treatment for shorter periods of time.

10 Nov 2004

Stem cell gene linked to a portion of one of the most common childhood brain cancers

Scientists at Johns Hopkins have linked a stem-cell gene to a portion of one of the most common childhood brain cancers, opening the door to tailored therapies that block the gene's tumor-promoting ability.

10 Nov 2004

Researchers find two locations in the human genome that may harbor genes that increase the risk of Alzheimer’s disease

Researchers at Columbia University Medical Center have found two locations in the human genome that may harbor genes that increase the risk of Alzheimer’s disease. If confirmed, they will be the first genes linked to Alzheimer’s disease since ApoE4 was discovered in 1993.

8 Nov 2004

Autophagy may even provide a clue to the mythical fountain of youth

The cells of higher organisms have an internal mechanism for chewing up and recycling parts of themselves, particularly in times of stress, like starvation and disease. But nobody is quite sure yet whether this recently discovered process protects cells, or causes damage.

5 Nov 2004

Trial of new type of drug that attacks amyloid

Neuroscientists at the Farber Institute for Neurosciences at Thomas Jefferson University in Philadelphia will begin a clinical trial testing a new type of drug that attacks amyloid, the protein substance that accumulates in the brains of Alzheimer’s disease patients.

4 Nov 2004

Genetic mutations could collectively raise bowel cancer risk

Cancer Research UK scientists at the University of Oxford have found that a number of genetic mutations could collectively raise bowel cancer risk, reporting their findings in the journal PNAS.

4 Nov 2004

Californians say yes on 71

With a clear mandate, the voters of California yesterday overwhelmingly approved Proposition 71, the California Stem Cell Research and Cures Initiative.

4 Nov 2004

New clues about how brain cells are damaged by Alzheimer's disease

University of Kentucky chemistry professor Allan Butterfield has uncovered new clues about how brain cells are damaged by Alzheimer's disease, evidence suggesting vitamin E may help prevent the debilitating illness.

1 Nov 2004

Warning on Alzheimer drug mix up

Janssen Pharmaceutica, manufacturer of the Alzheimer drug galantamine (Reminyl), says it has learned of 10 cases in which individuals who should have gotten Reminyl accidentally received the diabetes drug glimepiride (Amaryl).

1 Nov 2004

Researchers help define Apolipoprotein E's role in the formation of amyloid brain lesions and the memory loss associated with Alzheimer's disease

A research team led by University of South Florida neuroscientist Huntington Potter, PhD, CEO of the Johnnie B. Byrd Sr. Alzheimer's Center & Research Institute, for the first time has defined how the protein Apolipoprotein E (ApoE) contributes to both the formation of amyloid brain lesions and the memory loss associated with Alzheimer's disease.

1 Nov 2004

Interaction of nervous system proteins help researchers better understand age-related memory and hearing loss

In a finding that may one day help researchers better understand age-related memory and hearing loss, scientists have shown that two key nervous system proteins interact in a manner that helps regulate the transmission of signals in the nervous system.

29 Oct 2004

Alzheimer's Disease News and Research

Further Reading

Researchers find mutations in a multifunctional protein cause Parkinsonism

Eating apples may protect against Alzheimer's and Parkinsonism

A challenging job protects against the development of dementia

Researchers find effective treatment for Unusual Fever Syndrome caused by cold exposure

Financial impact of diabetes on the American economy

Atorvastatin slows down mental decline and improves depressive symptoms in people with Alzheimer’s disease

Dementia patients receiving long-term treatment with Reminyl may be able to stay at home for longer compared

Stem cell gene linked to a portion of one of the most common childhood brain cancers

Researchers find two locations in the human genome that may harbor genes that increase the risk of Alzheimer’s disease

Autophagy may even provide a clue to the mythical fountain of youth

Trial of new type of drug that attacks amyloid

Genetic mutations could collectively raise bowel cancer risk

Californians say yes on 71

New clues about how brain cells are damaged by Alzheimer's disease

Warning on Alzheimer drug mix up

Researchers help define Apolipoprotein E's role in the formation of amyloid brain lesions and the memory loss associated with Alzheimer's disease

Interaction of nervous system proteins help researchers better understand age-related memory and hearing loss

Trojan horse technique offers potential new therapeutic approach to Alzheimer's disease

Is NICE delivering the goods?

Scientists are trying to determine what goes on inside the brain when it sees a face

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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