Growth Factor News and Research

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Defective molecular master switch could lead to age-related macular degeneration

A signaling pathway controlled by transforming growth factor beta (TGF-beta) could be involved in the progression of age-related macular degeneration.

22 Jan 2019

Early studies and recent clinical trials on nerve growth factor

Nerve growth factor has been playing an important role in development of adult neurobiology. This is because of the regulatory functions that it possesses on survival, growth and differentiation of nerve cells in both of the central and peripheral nervous systems.

21 Jan 2019

TGF-beta signaling pathway in uterine cells protects against cancer

Two new mouse models of uterine cancer shed light on how this disease - the most common gynecological cancer in the U.S. - happens.

16 Jan 2019

Biomarkers identified that could predict the risk of stroke

Researchers have successfully developed two biomarkers that could help predict the risk of a heart condition and stroke.

7 Jan 2019

Newly discovered biomarkers can help identify heart condition in patients who have three 'clinical risks'

Researchers at the University of Birmingham have found two biomarkers that could be used to identify a heart condition known as atrial fibrillation in patients who have three 'clinical risks'.

7 Jan 2019

Study uncovers how skin ages, loses fat and immunity

Dermal fibroblasts are specialized cells deep in the skin that generate connective tissue and help the skin recover from injury. Some fibroblasts have the ability to convert into fat cells that reside under the dermis, giving the skin a plump, youthful look and producing a peptide that plays a critical role in fighting infections.

27 Dec 2018

Researchers present mechanisms, cellular targets involved with effects of TGF-Beta 1 muscle

The innate immune system comprises of various soluble factors that provide the first line of defense against pathogens.

21 Dec 2018

MUSC researchers identify potential therapeutic target for lung fibrosis

In an article published online by Frontiers in Endocrinology, researchers at the Medical University of South Carolina report that they have identified a potential therapeutic target for lung fibrosis or scarring.

19 Dec 2018

Self-powered bandage generates electricity, reduces healing time for skin wounds in rats

Skin has a remarkable ability to heal itself. But in some cases, wounds heal very slowly or not at all, putting a person at risk for chronic pain, infection and scarring. Now, researchers have developed a self-powered bandage that generates an electric field over an injury, dramatically reducing the healing time for skin wounds in rats.

19 Dec 2018

Novel insight on inflammatory regulation could pave way for effective pain therapies

A novel way in which the inflammatory response to pain is regulated has been described in the open-access journal eLife.

19 Dec 2018

High-intensity interval exercise could help combat cognitive dysfunction in obese people

It's fast-paced, takes less time to do, and burns a lot of calories. High-intensity interval exercise is widely recognized as the most time-efficient and effective way to exercise.

10 Dec 2018

Elevated hormone flags liver disease in mice with serious genomic disorder

Researchers have discovered that a hormone, fibroblast growth factor 21 (FGF21), is extremely elevated in mice with liver disease that mimics the same condition in patients with methylmalonic acidemia (MMA), a serious genomic disorder.

6 Dec 2018

DHEA therapy may help prevent bone loss and increase muscle mass in older women

Women 55 and older have an increased risk of bone and muscle loss but therapy with the hormone Dehydroepiandrosterone may help prevent bone loss and increase muscle mass in older women, according to a new study led by Catherine M. Jankowski, PhD, FACSM, an exercise physiologist and associate professor at the University of Colorado College of Nursing at the Anschutz Medical Campus.

5 Dec 2018

Researchers awarded $7 million funding in Pancreatic Cancer Collective’s 'New Therapies Challenge'

The Pancreatic Cancer Collective, the strategic partnership of the Lustgarten Foundation and Stand Up To Cancer, has awarded a total of $7 million in first-round "New Therapies Challenge" grants to seven teams of top cancer researchers to explore new pancreatic cancer treatments, the American Association for Cancer Research, the Scientific Partner of SU2C, announced today.

21 Nov 2018

New low-cost injectable hydrogel could help wounds heal faster

Researchers at the University of New Hampshire have created an easy-to-make, low-cost injectable hydrogel that could help wounds heal faster, especially for patients with compromised health issues.

21 Nov 2018

Stand Up to Cancer supports potential approach to more efficiently target pancreatic cancer

Research on a new way of deploying the immune system against pancreatic cancer, an exceptionally lethal cancer that has so far resisted new immunotherapies, will receive $1 million in initial funding from Stand Up to Cancer.

21 Nov 2018

Novel approach could provide painless, efficient alternative for treating eye diseases

Nanyang Technological University, Singapore scientists have developed a 'contact lens' patch with microneedles that could provide a painless and efficient alternative to current methods of treating eye diseases such as glaucoma and macular degeneration.

19 Nov 2018

New anti-HER2 drug shows promising anti-tumor activity in gullet, stomach and bowel cancers

An antibody that binds simultaneously to two distinct regions of the HER2 receptor to block the growth of cancer cells has shown promising signs of anti-tumor activity in a number of cancers including those of the gullet (esophagus), stomach and bowel.

14 Nov 2018

Small-stature in rainforest populations may be linked to cardiac adaptations

African and Asian rainforest hunter-gatherers share short stature, and now an international team of researchers has shown that this is an example of convergent adaptation that may also be linked to changes in cardiac development pathways.

13 Nov 2018

Researchers identify epigenetic changes that increase risk of type 2 diabetes

Small chemical changes in the DNA building blocks, which may be influenceable by lifestyle factors, can reduce the amount of IGFBP2. A DIfE / DZD research team has now reported in the journal Diabetes that these epigenetic changes increase the risk of type 2 diabetes.

8 Nov 2018

Growth Factor News and Research

Defective molecular master switch could lead to age-related macular degeneration

Early studies and recent clinical trials on nerve growth factor

TGF-beta signaling pathway in uterine cells protects against cancer

Biomarkers identified that could predict the risk of stroke

Newly discovered biomarkers can help identify heart condition in patients who have three 'clinical risks'

Study uncovers how skin ages, loses fat and immunity

Researchers present mechanisms, cellular targets involved with effects of TGF-Beta 1 muscle

MUSC researchers identify potential therapeutic target for lung fibrosis

Self-powered bandage generates electricity, reduces healing time for skin wounds in rats

Novel insight on inflammatory regulation could pave way for effective pain therapies

High-intensity interval exercise could help combat cognitive dysfunction in obese people

Elevated hormone flags liver disease in mice with serious genomic disorder

DHEA therapy may help prevent bone loss and increase muscle mass in older women

Researchers awarded $7 million funding in Pancreatic Cancer Collective’s 'New Therapies Challenge'

New low-cost injectable hydrogel could help wounds heal faster

Stand Up to Cancer supports potential approach to more efficiently target pancreatic cancer

Novel approach could provide painless, efficient alternative for treating eye diseases

New anti-HER2 drug shows promising anti-tumor activity in gullet, stomach and bowel cancers

Small-stature in rainforest populations may be linked to cardiac adaptations

Researchers identify epigenetic changes that increase risk of type 2 diabetes

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