Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Mucosal COVID-19 boosters outperform mRNA shots in preventing upper airway infections

Aerosolized mucosal vaccines show promise in controlling SARS-CoV-2, offering greater protection and immune response than intramuscular bivalent mRNA boosters.

5 Sep 2024

New insights into stiff-person syndrome, advancing diagnosis and treatment

Research explores the complexities of diagnosing and treating stiff-person syndrome, emphasizing the uncertain role of GAD antibodies and the promise of novel therapies.

5 Sep 2024

WHO unveils global framework for investigating origins of novel pathogens

With the support of the Scientific Advisory Group for the Origins of Novel Pathogens (SAGO), the World Health Organization (WHO) has published a global framework to help Member States comprehensively investigate the origins of new and re-emerging pathogens.

4 Sep 2024

New immunotherapy approach shows promise for minimizing spinal cord injury damage

WashU Medicine researchers have designed, in mice, an approach to minimizing the damage from a spinal cord injury through the use of engineered immune cells.

4 Sep 2024

Does air pollution drive dementia?

Chronic air pollution exposure is a key factor in dementia development, with pollutants like PM2.5 and NO2 linked to cognitive decline and neurodegeneration.

4 Sep 2024

Study shows how troriluzole can target early-stage alterations associated with Alzheimer's

In a recent development in Alzheimer's disease research, Auburn University scientists have studied a new drug, troriluzole, that can prevent brain changes leading to memory loss and cognitive decline in a mouse model of the disease.

3 Sep 2024

Intranasal vaccine shows broad SARS-CoV-2 variant protection

Study demonstrates that a single-dose intranasal live-attenuated vaccine, CDO-7N-1, provides broad protection against SARS-CoV-2 and its variants by inducing potent immune responses, including neutralizing antibodies and T-cell activity, in animal models.

1 Sep 2024

UCLA team develops automated HER2 scoring system with deep learning and pyramid sampling

HER2 is a critical protein that plays a pivotal role in breast cancer cell growth and aggressiveness. Its expression level is a key indicator for treatment decisions, including the use of HER2-targeted therapies.

30 Aug 2024

New finger-prick blood test could revolutionize Alzheimer’s screening

GPs could soon be able to screen their patients for Alzheimer’s Disease (AD) using a simple handheld device developed by Monash engineers.

30 Aug 2024

Obesity increases the risk of SARS-CoV-2 infection by 34%

Obesity is linked to a 34% higher risk of SARS-CoV-2 infection upon exposure, highlighting the importance of weight management in COVID-19 prevention.

30 Aug 2024

Acute kidney injury doubles dementia risk, study finds

Study reveals a significant association between acute kidney injury (AKI) and an increased risk of dementia, particularly in cases of severe or recurrent AKI.

29 Aug 2024

Climate change linked to increased risk of foodborne illness from Salmonella enterica

Climate change will increase the risk of the foodborne illness from Salmonella enterica, according to a new study. The research was published today in Applied and Environmental Microbiology, a journal of the American Society for Microbiology.

29 Aug 2024

New insights into AD pathogenesis and treatment

The main text of the study details the experiments conducted to understand the role of IL-24 in AD-like conditions. It describes the methods used, including single-cell RNA sequencing, and the animal models employed to mimic AD. The findings indicate that MRSA infection leads to increased IL-24 in keratinocytes, which in turn heightens type 2 immune responses and worsens AD symptoms.

29 Aug 2024

Researchers identify key cellular interactions driving Alzheimer's and aging

An analysis of more than 1.6 million brain cells from older adults has captured the cellular changes that occur in the early stages of Alzheimer's disease, potentially revealing new routes for preventing the most common cause of dementia in older individuals.

28 Aug 2024

PET imaging and proteomics reveal distinct protein signatures in Alzheimer's disease progression

Researchers used PET imaging and proteomic analysis of cerebrospinal fluid to study amyloid β and tau tangle loads in Alzheimer's patients, identifying 127 proteins linked to disease progression. The findings highlight distinct molecular pathways and potential therapeutic targets.

28 Aug 2024

SARS-CoV-2 evolves differently in the brain, revealing critical insights into viral tropism

Study investigates the evolution of SARS-CoV-2 within the central nervous system (CNS) compared to the lungs in mice, revealing higher viral divergence in the CNS and highlighting the critical role of the furin cleavage site (FCS) in viral tropism and compartmentalization.

27 Aug 2024

Pathology News and Research

Further Reading

Mucosal COVID-19 boosters outperform mRNA shots in preventing upper airway infections

New insights into stiff-person syndrome, advancing diagnosis and treatment

WHO unveils global framework for investigating origins of novel pathogens

New immunotherapy approach shows promise for minimizing spinal cord injury damage

Does air pollution drive dementia?

Study shows how troriluzole can target early-stage alterations associated with Alzheimer's

Intranasal vaccine shows broad SARS-CoV-2 variant protection

UCLA team develops automated HER2 scoring system with deep learning and pyramid sampling

New finger-prick blood test could revolutionize Alzheimer’s screening

Obesity increases the risk of SARS-CoV-2 infection by 34%

Acute kidney injury doubles dementia risk, study finds

Climate change linked to increased risk of foodborne illness from Salmonella enterica

New insights into AD pathogenesis and treatment

Researchers identify key cellular interactions driving Alzheimer's and aging

PET imaging and proteomics reveal distinct protein signatures in Alzheimer's disease progression

SARS-CoV-2 evolves differently in the brain, revealing critical insights into viral tropism

Exploring early detection of Alzheimer's disease through non-cognitive symptoms

Children and adolescents experience unique long COVID symptoms

Multiple sclerosis patients less likely to have molecular hallmarks of Alzheimer's disease

Portable OCT otoscope improves diagnostic capabilities in hearing clinics

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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