Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Novel molecular signaling pathway found to play a crucial role in maintaining the skin barrier

Our skin–the body's largest organ–provides the first line of defense against infections and many other threats to our health.

9 Aug 2024

Cross-reactive T cells link SARS-CoV-2 to autoimmune triggers in MIS-C

Research identifies cross-reactive T cells targeting both SARS-CoV-2 and human SNX8 protein, providing insights into the autoimmune mechanisms driving MIS-C in children.

8 Aug 2024

Drug shows new promise in treating breast cancer with brain metastases or recurrent glioblastoma

A drug effective in treating breast cancer shows new promise in addressing breast cancer with brain metastases or recurrent glioblastoma, as reported by results of a prospective window-of-opportunity trial at the University of Texas Health Science Center at San Antonio (UT Health San Antonio).

8 Aug 2024

Breakthrough discovery could boost stem-cell transplants by improving cell mobilization

A discovery by a three-member Albert Einstein College of Medicine research team may boost the effectiveness of stem-cell transplants, commonly used for patients with cancer, blood disorders, or autoimmune diseases caused by defective stem cells, which produce all the body's different blood cells.

8 Aug 2024

Polycystic ovary syndrome linked to greater risk of disordered eating in women

Women with the common reproductive and metabolic condition polycystic ovary syndrome (PCOS) face a greater risk of developing bulimia, binge eating disorder and disordered eating, according to new research published in The Journal of Clinical Endocrinology & Metabolism.

8 Aug 2024

New technique reveals abnormalities in motor neurone disease

Pathological abnormalities associated with motor neurone disease have been identified using a new technique developed at the University of Birmingham.

8 Aug 2024

Research finds synaptic strength key to maintaining memory in old age

Over the course of life, memory fades with varying degrees, robbing older people of the ability to recollect personal experiences.

7 Aug 2024

High blood sugar at stroke admission linked to poor prognosis

Having higher than usual blood sugar levels at the time of hospital admission for an ischemic stroke significantly increases the risk of a poor functional prognosis or death within three months of the stroke.

7 Aug 2024

Novel blood test could predict chronic lung disease in preterm babies within hours of birth

A blood test can help predict which preterm babies will go onto develop chronic lung disease, allowing for earlier diagnosis and more targeted treatments, according to a new study.

7 Aug 2024

Discovery of Tr1 cells as a barrier to cancer immunotherapy offers new hope for treatment

Immunobiologists Robert Schreiber, PhD, (left) and Hussein Sultan, PhD, of Washington University School of Medicine in St. Louis, found that a subset of immune cells that normally puts the brakes on the immune system to prevent it from attacking the body's healthy cells inadvertently also dampens cancer immunotherapy.

7 Aug 2024

Researchers uncover immune system barrier to cancer treatment

By recruiting the immune system to combat tumor cells, immunotherapy has improved survival rates, offering hope to millions of cancer patients. However, only about one in five people responds favorably to these treatments.

7 Aug 2024

Study uncovers roles of certain brain cells in Alzheimer's plaque formation

A study in Nature Neuroscience found that both neurons and oligodendrocytes contribute to amyloid-β plaque burden in Alzheimer's disease, highlighting new therapeutic targets.

7 Aug 2024

Cambridge experts question efficacy and practicality of new amyloid immunotherapy drugs

Cambridge researchers have cast doubt on whether new amyloid immunotherapy drugs will have the desired effect of significantly reducing the impact of Alzheimer's disease.

6 Aug 2024

AI model matches radiologists in detecting clinically significant prostate cancer on MRI

A deep learning model performs at the level of an abdominal radiologist in the detection of clinically significant prostate cancer on MRI, according to a study published today in Radiology, a journal of the Radiological Society of North America (RSNA).

6 Aug 2024

Combining radiation with chemotherapy enhances survival in oligometastatic pancreatic cancer

Researchers from The University of Texas MD Anderson Cancer Center demonstrated that adding metastasis-directed radiation therapy to standard-of-care chemotherapy improved progression-free survival (PFS) in patients with oligometastatic pancreatic cancer.

5 Aug 2024

UCLA launches groundbreaking clinical trial for vaccine targeting aggressive pediatric brain cancer

In an effort to combat one of the most lethal forms of pediatric brain cancer, researchers at the UCLA Health Jonsson Comprehensive Cancer Center are launching a first-of-its-kind clinical trial to evaluate the safety and effectiveness of a cancer vaccine targeting H3 G34-mutant diffuse hemispheric glioma, a highly aggressive brain tumor that is typically found in adolescents and young adults.

5 Aug 2024

Pathology News and Research

Further Reading

Novel molecular signaling pathway found to play a crucial role in maintaining the skin barrier

Cross-reactive T cells link SARS-CoV-2 to autoimmune triggers in MIS-C

Drug shows new promise in treating breast cancer with brain metastases or recurrent glioblastoma

Breakthrough discovery could boost stem-cell transplants by improving cell mobilization

Polycystic ovary syndrome linked to greater risk of disordered eating in women

New technique reveals abnormalities in motor neurone disease

Research finds synaptic strength key to maintaining memory in old age

High blood sugar at stroke admission linked to poor prognosis

Novel blood test could predict chronic lung disease in preterm babies within hours of birth

Discovery of Tr1 cells as a barrier to cancer immunotherapy offers new hope for treatment

Researchers uncover immune system barrier to cancer treatment

Study uncovers roles of certain brain cells in Alzheimer's plaque formation

Cambridge experts question efficacy and practicality of new amyloid immunotherapy drugs

AI model matches radiologists in detecting clinically significant prostate cancer on MRI

Combining radiation with chemotherapy enhances survival in oligometastatic pancreatic cancer

UCLA launches groundbreaking clinical trial for vaccine targeting aggressive pediatric brain cancer

Cholesterol imbalance linked to neurodegeneration, study suggests potential strategies for intervention

Study finds fourfold increase in risk of overt hypothyroidism after diagnosis of gestational subclinical hypothyroidism

St. Jude develops cost-effective genetic panel for pediatric cancer diagnosis

Oropouche virus: Emerging threats and unanswered questions

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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