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Researchers identify series of molecules involved in regeneration of damaged nerves

Researchers at Nagoya University have identified the series of molecules involved in the regeneration of damaged nerves in roundworm, showing that it largely overlaps with the signals used by the intrinsic removal system to take up and process dying cells.

24 Aug 2018

Study findings shed light on fundamental feature of nerve repair

Through a study of roundworm nerve cells with severed axons, researchers at Nagoya University showed that a signaling cascade that normally functions in promoting the phagocytosis of apoptotic cells also acts in inducing axon regeneration.

24 Aug 2018

Advanced microscopes determine structure of molecular complex implicated in several cancers

In a study published today in Science, UT Southwestern and Rockefeller University researchers used advanced microscopes to determine at atomic resolution the structure of a molecular complex implicated in birth defects and several cancers.

24 Aug 2018

Researchers complete testing a new drug to treat rheumatoid arthritis

An international research group led by Charité - Universitätsmedizin Berlin has completed testing a new drug to treat rheumatoid arthritis.

23 Aug 2018

Research identifies cell signaling pathways related to endocannabinoid system in worms

Like mammals, parasitic worms have an endocannabinoid system that may help the worm and the hosts it infects survive by reducing pain and inflammation in the host, according to a "wild" new discovery by an interdisciplinary research team at the University of California, Riverside.

23 Aug 2018

UTA researcher receives NIH grant to explore ways to boost innate immunity

A UTA researcher has won a five-year, $1.8 million grant from the National Institutes of Health to look at new ways to harness the body's own defense responses to fight pathogens like bacteria.

21 Aug 2018

Aravive Biologics gains Fast Track Designation for AVB-S6-500 from U.S. FDA

Aravive Biologics, Inc. announced today that the U.S. Food and Drug Administration has granted Fast Track Designation to AVB-S6-500 as a potential treatment for platinum-resistant recurrent ovarian cancer.

20 Aug 2018

Thrombospondin-1 contributes to development of aortic aneurysm in mice and humans, study finds

Researchers centered at the University of Tsukuba and Kansai Medical University in Japan reveal matricellular protein Thrombospondin-1 (Thbs1) contributes to the development of aortic aneurysm in mice and humans.

20 Aug 2018

Researchers identify way to grow immune cells at large scale for preventing cancer reoccurrence

For the first time, Mount Sinai researchers have identified a way to make large numbers of immune cells that can help prevent cancer reoccurrence, according to a study published in August in Cell Reports.

15 Aug 2018

A class of proteins shown to be effective in reducing drug-seeking behaviors

A class of proteins that has generated significant interest for its potential to treat diseases, has for the first time, been shown to be effective in reducing relapse, or drug-seeking behaviors, in a preclinical study.

14 Aug 2018

UAB study shows how ion channel differentiates newborn and mature neurons in the brain

The dentate gyrus of the hippocampus is part of the brain that helps form memories. It is also one of just two areas in the adult brain where new neurons are continuously formed.

13 Aug 2018

Scientists uncover mechanisms responsible for development of fibrosis

Idiopathic pulmonary fibrosis is an incurable lung disease of unknown origin with limited treatment options. Research suggests that the signaling molecule WNT5A plays a key role in the pathogenic process.

10 Aug 2018

Ground-breaking discovery offers new hope for treatment of Alzheimer’s, other neurological diseases

There is new hope for the treatment of Alzheimer’s and other neurological diseases following a ground-breaking discovery made by an Australian-Chinese research collaboration.

10 Aug 2018

Novel discovery offers hope for treatment of Alzheimer's and other neurological diseases

There is new hope for the treatment of Alzheimer's and other neurological diseases following a ground-breaking discovery made by an Australian-Chinese research collaboration.

10 Aug 2018

Silencing of GULP1 gene expression plays important role in ovarian carcinogenesis

Johns Hopkins researchers in collaboration with Insilico Medicine, a biotechnology company based in Rockville Maryland, identify that silencing of the GULP1 gene expression by methylation plays an important role in ovarian carcinogenesis.

7 Aug 2018

Researchers find ways to render curcumin soluble and deliver it to infected tumors

In India and other countries in Southeast Asia, curcumin is often used as a spice in cooking, particularly chicken or fish. It is known for its therapeutic effect and as a way to kill germs present in raw meet.

7 Aug 2018

Researchers develop 3D model of human placenta

The placenta is the organ connecting mother and embryo. Its main functions are the exchange of nutrients, gases and metabolic products and the production of hormones and other substances essential for embryonic development.

3 Aug 2018

Researchers discover key piece for slowing colorectal cancer subtype

Inhibiting the Jagged 1 protein in mice prevents the proliferation and growth of colon and rectal tumors. What is more, this approach to the disease permits the removal of existing tumors.

2 Aug 2018

Newly identified target may lead to discovery of treatments for chronic inflammatory diseases

Inflammation is part of the body's natural healing process. But when it becomes chronic, inflammation can lead to cancer, Alzheimer's disease and other conditions.

26 Jul 2018

New control system regulates morphology, orientation of cells constituting animal tissues

A collaborative research group led by Kumamoto University has developed a new control system for regulating the morphology and orientation of cells that constitute animal tissues.

25 Jul 2018

Signaling Pathway News and Research

Researchers identify series of molecules involved in regeneration of damaged nerves

Study findings shed light on fundamental feature of nerve repair

Advanced microscopes determine structure of molecular complex implicated in several cancers

Researchers complete testing a new drug to treat rheumatoid arthritis

Research identifies cell signaling pathways related to endocannabinoid system in worms

UTA researcher receives NIH grant to explore ways to boost innate immunity

Aravive Biologics gains Fast Track Designation for AVB-S6-500 from U.S. FDA

Thrombospondin-1 contributes to development of aortic aneurysm in mice and humans, study finds

Researchers identify way to grow immune cells at large scale for preventing cancer reoccurrence

A class of proteins shown to be effective in reducing drug-seeking behaviors

UAB study shows how ion channel differentiates newborn and mature neurons in the brain

Scientists uncover mechanisms responsible for development of fibrosis

Ground-breaking discovery offers new hope for treatment of Alzheimer’s, other neurological diseases

Novel discovery offers hope for treatment of Alzheimer's and other neurological diseases

Silencing of GULP1 gene expression plays important role in ovarian carcinogenesis

Researchers find ways to render curcumin soluble and deliver it to infected tumors

Researchers develop 3D model of human placenta

Researchers discover key piece for slowing colorectal cancer subtype

Newly identified target may lead to discovery of treatments for chronic inflammatory diseases

New control system regulates morphology, orientation of cells constituting animal tissues

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