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Understanding how biological sex and gender inequities contribute to suboptimal sepsis treatment

Sepsis continues to be a leading cause of mortality in ICUs worldwide. Despite advances in early detection and treatment, standardized antibiotic dosing frequently ignores patient-level variability-especially that associated with sex-related physiology and gender-influenced care disparities.

31 Oct 2025

Novel nanoparticles can deliver an immune-stimulating molecule directly to ovarian tumors

Cancer immunotherapy, which uses drugs that stimulate the body's immune cells to attack tumors, is a promising approach to treating many types of cancer. However, it doesn't work well for some tumors, including ovarian cancer.

31 Oct 2025

Intraoperative radiation reduces the recurrence rate of pancreatic cancer

Using targeted radiation during surgery - referred to as intraoperative radiation - to eliminate pancreatic cancer cells that have spread to areas around the pancreas, investigators at Johns Hopkins have been able to reduce the recurrence rate around the pancreas to 5%.

30 Oct 2025

Unusual presentation of vulvar mucinous cyst with multiple bartholin cysts in a reproductive-age woman

A new case report was published in Volume 12 of Oncoscience on October 9, 2025, titled "Vulvar mucinous cyst mimicking common lesions with concurrent multiple bartholin cysts in a reproductive-age woman: A rare case report and review of literature."

30 Oct 2025

Therapeutic potential of Scleromitrion diffusum in gastric cancer treatment

Gastric cancer remains a major global health challenge, characterized by high mortality and limited therapeutic efficacy, especially in advanced stages.

30 Oct 2025

Understanding the role of m6A methylation in acute lung injury pathogenesis

Acute lung injury (ALI) is a critical clinical condition characterized by diffuse inflammation of the lung parenchyma and intractable hypoxemia, typically caused by factors, such as trauma, pneumonia, shock, and sepsis.

30 Oct 2025

Fundamental challenges and cutting-edge strategies in developing new GBM CAR-T therapies

Glioblastoma (GBM), the most aggressive primary brain tumor, continues to portend a poor prognosis with median survival under two years, despite standard care involving surgery, radiation, and temozolomide chemotherapy.

30 Oct 2025

Veterans with post-traumatic brain injury epilepsy more likely to have higher mortality rates

Military veterans who develop epilepsy after a traumatic brain injury may have a higher mortality rate in the following years than veterans who develop epilepsy with no previous traumatic brain injury, according to a study published on October 29, 2025, in Neurology®, the medical journal of the American Academy of Neurology.

30 Oct 2025

Research identifies biomarkers in blood to fine-tune breast cancer interventions

Doctors may be able to spare patients unnecessarily aggressive breast cancer treatments by collecting and testing cancer cells in patients' blood, research from the University of Michigan and the University of Kansas suggests.

30 Oct 2025

Computational model predicts the hemodynamic response of patients following atrial fibrillation

Atrial fibrillation (AFib) is a cardiac disorder in which the chambers of the heart beat rapidly and irregularly. It's the most common type of arrhythmia and the leading cardiac cause of stroke.

29 Oct 2025

3D-printing soft robot delivers hydrogels to the vocal cord surgical site to reconstruct tissues

After vocal cord surgery, many patients develop stiff vocal folds that impact their ability to speak. Hydrogels can help prevent this by promoting healing, but delivering hydrogels to the vocal cords is difficult.

29 Oct 2025

NYU Langone experts treat 32-year-old Westchester mom for breast cancer while pregnant

Christina, a former teacher, was 32 years old when she found out she was pregnant with her second child. Two weeks later, she received the shocking news that she had breast cancer.

29 Oct 2025

Doctor tripped up by $64K bill for ankle surgery and hospital stay

Physician Lauren Hughes was heading to see patients at a clinic about 20 miles from her Denver home in February when another driver T-boned her Subaru, totaling it. She was taken by ambulance to the closest hospital, Platte Valley Hospital.

29 Oct 2025

Preliminary study shows intraoperative radiation's success against pancreatic cancer spread

29 Oct 2025

Wireless retinal implant restores sight in patients blinded by advanced macular degeneration

A new trial shows that a wireless subretinal implant, the PRIMA system, restored central vision in patients with geographic atrophy caused by age-related macular degeneration. After one year, 81% achieved clinically meaningful vision gains and most could read at home using prosthetic vision.

28 Oct 2025

Innovative approach to enhancing laser lithotripsy for kidney stones

During a procedure known as laser lithotripsy, urologists use a small, video-guided laser to blast painful, potentially damaging kidney stones to smithereens.

28 Oct 2025

First self-powered spinal implant can transmit real-time data from inside the body

A collaboration between civil engineering and neurosurgery at the University of Pittsburgh could change how spinal fusion surgery is performed and monitored. Associate Professors Amir Alavi, Nitin Agarwal, and D. Kojo Hamilton have received a $352,213 National Institutes of Health (NIH) R21 grant to develop the first self-powered spinal implant capable of transmitting real-time data from inside the body.

28 Oct 2025

Landmark trial shows drug-eluting balloon as effective option for in-stent restenosis

Results from the first randomized clinical trial in the United States to compare a sirolimus-eluting balloon (DEB) to control group consisting of drug-eluting stent (DES) and balloon angioplasty (BA) for the treatment of bare-metal and DES in-stent restenosis (ISR) deemed DEB to be noninferior to conventional therapies.

28 Oct 2025

Mount Sinai receives $4.5 million grant to investigate neural mechanisms underlying bipolar disorder

The Icahn School of Medicine at Mount Sinai is pleased to announce it has received a three-year, $4.5 million grant from BD2: Breakthrough Discoveries for thriving with Bipolar Disorder to investigate the neural mechanisms underlying bipolar disorder and pioneer novel neuromodulation-based treatment strategies.

28 Oct 2025

$Reducing femoral fractures in total hip replacement with safer implant designs$

Reducing femoral fractures in total hip replacement with safer implant designs

As populations continue to age, total hip replacement (THR) is becoming an increasingly common surgical procedure.

28 Oct 2025

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Surgery News and Research

Understanding how biological sex and gender inequities contribute to suboptimal sepsis treatment

Novel nanoparticles can deliver an immune-stimulating molecule directly to ovarian tumors

Intraoperative radiation reduces the recurrence rate of pancreatic cancer

Unusual presentation of vulvar mucinous cyst with multiple bartholin cysts in a reproductive-age woman

Therapeutic potential of Scleromitrion diffusum in gastric cancer treatment

Understanding the role of m6A methylation in acute lung injury pathogenesis

Fundamental challenges and cutting-edge strategies in developing new GBM CAR-T therapies

Veterans with post-traumatic brain injury epilepsy more likely to have higher mortality rates

Research identifies biomarkers in blood to fine-tune breast cancer interventions

Computational model predicts the hemodynamic response of patients following atrial fibrillation

3D-printing soft robot delivers hydrogels to the vocal cord surgical site to reconstruct tissues

NYU Langone experts treat 32-year-old Westchester mom for breast cancer while pregnant

Doctor tripped up by $64K bill for ankle surgery and hospital stay

Preliminary study shows intraoperative radiation's success against pancreatic cancer spread

Wireless retinal implant restores sight in patients blinded by advanced macular degeneration

Innovative approach to enhancing laser lithotripsy for kidney stones

First self-powered spinal implant can transmit real-time data from inside the body

Landmark trial shows drug-eluting balloon as effective option for in-stent restenosis

Mount Sinai receives $4.5 million grant to investigate neural mechanisms underlying bipolar disorder

Reducing femoral fractures in total hip replacement with safer implant designs

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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