Inflammation News and Research

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Celgene reports results from placebo-controlled phase II trial in patients with Behçet's disease

Celgene International Sàrl, a subsidiary of Celgene Corporation today presented results from a randomized, placebo-controlled phase II trial in patients with Behçet's disease at EULAR, the European Congress of Rheumatology annual meeting in Madrid.

14 Jun 2013

Overweight, obese ERA patients require twice as much drug therapy to achieve successful remission

A new study presented today at EULAR 2013, the Annual Congress of the European League Against Rheumatism, shows that overweight and obese patients are less likely to achieve successful remission in early rheumatoid arthritis compared to those of normal weight.

14 Jun 2013

Ischaemic heart disease patients at risk after 1 week of treatment

New study data presented today at EULAR 2013, the Annual Congress of the European League Against Rheumatism, demonstrate a high prevalence of NSAID prescriptions in patients at risk of ischaemic heart disease.

14 Jun 2013

Novel antibody biomarkers could significantly improve diagnosis in RA, study shows

Data presented at EULAR 2013, the Annual Congress of the European League Against Rheumatism, show that novel antibody biomarkers could significantly improve diagnosis in rheumatoid arthritis.

14 Jun 2013

Depression, antidepressant use may increase risk for diabetes and CVD in postmenopausal women

Postmenopausal women who use antidepressant medication or suffer from depression might be more likely to have a higher body mass index, larger waist circumference and inflammation-all associated with increased risk for diabetes and cardiovascular disease, according to a study led by University of Massachusetts Medical School investigator Yunsheng Ma, PhD, MD, MPH, and published in the June 13 issue of the American Journal of Public Health.

14 Jun 2013

Nervous system and nerve-growth factor play major role in arthritis

Arthritis is a debilitating disorder affecting one in 10 Canadians, with pain caused by inflammation and damage to joints.

14 Jun 2013

Xgeva receives FDA approval for treating giant cell tumor of the bone

The U.S. Food and Drug Administration today expanded the approved use of Xgeva (denosumab) to treat adults and some adolescents with giant cell tumor of the bone, a rare and usually non-cancerous tumor.

14 Jun 2013

Study: Tocilizumab is effective in children with juvenile idiopathic arthritis

A new study presented today at EULAR 2013, the Annual Congress of the European League Against Rheumatism shows that tocilizumab is efficacious and leads to a sustained clinically meaningful improvement in children with polyarticular Juvenile Idiopathic Arthritis (pcJIA).

13 Jun 2013

AMPLE trial demonstrates similar safety profiles and efficacy between abatacept and adalimumab in RA

Data from AMPLE presented at EULAR 2013, the Annual Congress of the European League Against Rheumatism, demonstrate comparable efficacy and similar safety profiles between subcutaneous abatacept (ABA) and adalimumab (ADA).

13 Jun 2013

Pregnancy carried to childbirth increases risk of ACPA-negative RA

Epidemiological data presented today at EULAR 2013, the Annual Congress of the European League Against Rheumatism, demonstrate that pregnancy carried to childbirth (parity) increases the risk of ACPA-negative rheumatoid arthritis.

13 Jun 2013

African-Americans have much greater decrease in their sense of smell, study finds

The ability to distinguish between odors declines steadily with age, but a new study shows that African-Americans have a much greater decrease in their sense of smell than Caucasians.

13 Jun 2013

Few cups of hot cocoa may help obese people better control inflammation-related diseases

A few cups of hot cocoa may not only fight off the chill of a winter's day, but they could also help obese people better control inflammation-related diseases, such as diabetes, according to Penn State researchers.

13 Jun 2013

Study on the development of internet-based physical activity intervention presented at EULAR 2013

Results of the first study involving RA patients in the development of an internet-based physical activity intervention were presented at EULAR 2013, the Annual Congress of the European League Against Rheumatism.

13 Jun 2013

Elevated levels of inflammatory biomarkers in individuals associated with high risk of COPD exacerbations

Simultaneously elevated levels of the biomarkers C-reactive protein, fibrinogen and leukocyte count in individuals with chronic obstructive pulmonary disease (COPD) were associated with increased risk of having exacerbations, even in those with milder COPD and in those without previous exacerbations, according to a study in the June 12 issue of JAMA.

12 Jun 2013

Researchers to launch Phase II clinical trial to investigate potential new therapy for sickle cell anemia

Seeking to improve the lives of sickle cell anemia sufferers around the world, researchers from the La Jolla Institute for Allergy and Immunology, the Dana-Farber/Children's Hospital Cancer Center in Boston and the BloodCenter of Wisconsin in Milwaukee and others are preparing to launch Phase II of a clinical trial to investigate a potential new therapy for reducing the disorder's severest symptoms.

12 Jun 2013

Hebrew University student develops drug formulations to treat illnesses through skin applications

New, more efficient drug formulations designed to treat illnesses through skin applications -- thus avoiding serious side effects associated with oral drug-taking -- have been developed by a student at the Hebrew University of Jerusalem.

12 Jun 2013

New SPECT and MR imaging systems unveiled at SNMMI's 2013 Annual Meeting

The Society of Nuclear Medicine and Molecular Imaging's 2013 Annual Meetingmarks the unveiling of the successful application of a new preclinical hybrid molecular imaging system-single photon emission tomography and magnetic resonance -which has exceptional molecular imaging capabilities in terms of potential preclinical and clinical applications, technological advancement at a lower cost, and reduction of patient exposure to ionizing radiation.

12 Jun 2013

Research could lead to new ways to combat chlamydia

A protein secreted by the chlamydia bug has a very unusual structure, according to scientists in the School of Medicine at The University of Texas Health Science Center San Antonio. The discovery of the protein's shape could lead to novel strategies for diagnosing and treating chlamydia, a sexually transmitted disease that infects an estimated 2.8 million people in the U.S. each year.

12 Jun 2013

Clinical trial underway for potential new treatment for type 1 diabetes

A clinical trial is underway for a potential new treatment for type 1 diabetes that could eventually mean patients are able to reduce insulin treatment from several times a day to only once or twice a week. The new treatment is a direct result of research to understand the genetics of the disease.

11 Jun 2013

Rapamycin improves cardiac function in mice suffering from age-related heart disease

Elderly mice suffering from age-related heart disease saw a significant improvement in cardiac function after being treated with the FDA-approved drug rapamycin for just three months.

11 Jun 2013

Inflammation News and Research

Celgene reports results from placebo-controlled phase II trial in patients with Behçet's disease

Overweight, obese ERA patients require twice as much drug therapy to achieve successful remission

Ischaemic heart disease patients at risk after 1 week of treatment

Novel antibody biomarkers could significantly improve diagnosis in RA, study shows

Depression, antidepressant use may increase risk for diabetes and CVD in postmenopausal women

Nervous system and nerve-growth factor play major role in arthritis

Xgeva receives FDA approval for treating giant cell tumor of the bone

Study: Tocilizumab is effective in children with juvenile idiopathic arthritis

AMPLE trial demonstrates similar safety profiles and efficacy between abatacept and adalimumab in RA

Pregnancy carried to childbirth increases risk of ACPA-negative RA

African-Americans have much greater decrease in their sense of smell, study finds

Few cups of hot cocoa may help obese people better control inflammation-related diseases

Study on the development of internet-based physical activity intervention presented at EULAR 2013

Elevated levels of inflammatory biomarkers in individuals associated with high risk of COPD exacerbations

Researchers to launch Phase II clinical trial to investigate potential new therapy for sickle cell anemia

Hebrew University student develops drug formulations to treat illnesses through skin applications

New SPECT and MR imaging systems unveiled at SNMMI's 2013 Annual Meeting

Research could lead to new ways to combat chlamydia

Clinical trial underway for potential new treatment for type 1 diabetes

Rapamycin improves cardiac function in mice suffering from age-related heart disease

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