B Cell News and Research

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Special MRI technique predicts onset of mild cognitive impairment and cognitive decline

A special MRI technique that detects iron levels in different regions of the brain can predict the onset of mild cognitive impairment and cognitive decline in cognitively unimpaired older adults, potentially creating a pathway to earlier interventions, according to a study published today in Radiology, a journal of the Radiological Society of North America.

9 Sep 2025

Study maps gene activity across pregnancy breastfeeding and post-weaning stages

In a study in mice, researchers have identified genes associated with the dramatic transformation of the mammary gland in pregnancy, breastfeeding, and after breastfeeding as it returns to its resting state.

9 Sep 2025

Researchers reveal why no level of air pollution is safe for respiratory health

A review in the Journal of Clinical Investigation shows how particulate matter damages the lungs through oxidative stress, inflammation, and immune disruption. It links air pollution to asthma, COPD, lung cancer, infections, and millions of premature deaths, with no safe exposure threshold.

9 Sep 2025

IFITM3 found to be critical regulator of immunotherapy sensitivity in small cell lung cancer

New research presented identifies interferon-induced transmembrane protein 3 (IFITM3) as a critical regulator of immunotherapy sensitivity in small cell lung cancer (SCLC), offering a promising new avenue for overcoming resistance to PD-1/PD-L1 checkpoint blockade.

9 Sep 2025

Amino acid homocysteine plays a key role in aortic stiffening

In addition to cholesterol, the amino acid homocysteine also plays a role in aortic stiffening. Researchers from Graz University of Technology, the University of Graz and the Medical University of Graz were able to prove this in a new study.

9 Sep 2025

Researchers uncover a previously unknown mechanism behind chromosome end protection

Researchers have uncovered a previously unknown mechanism that safeguards the chromosome ends from being mistakenly repaired by the cell.

9 Sep 2025

New tool can predict where deadly brain cancer might reappear

Glioblastoma is a devastatingly effective brain cancer. Doctors can cut it out or blast it with radiation, but that only buys time. The cancer has an insidious ability to hide enough tumor cells in tissue around the tumor to allow it to return as deadly as ever.

9 Sep 2025

Monitoring ctDNA can personalize the use of consolidation immunotherapy in patients with LS-SCLC

A new study presented at the International Association for the Study of Lung Cancer 2025 World Conference on Lung Cancer (WCLC) demonstrates that monitoring circulating tumor DNA (ctDNA) can refine and personalize the use of consolidation immunotherapy in patients with limited-stage small cell lung cancer (LS-SCLC).

9 Sep 2025

New feedback mechanism in the brain could open avenues for treating people with sleep disorders

As every bodybuilder knows, a deep, restful sleep boosts levels of growth hormone to build strong muscle and bone and burn fat.

9 Sep 2025

'Resistin like molecule gamma' punches holes into heart cells after myocardial infarction

Nina Kumowski, MD, of the Department of Radiology and Center for Systems Biology at Massachusetts General Hospital, is the lead author and Matthias Nahrendorf, MD, PhD of the Department of Radiology and Center for Systems Biology at MGH, is the senior author of a paper published in Science, "Resistin-like molecule γ attacks cardiomyocyte membranes and promotes ventricular tachycardia."

9 Sep 2025

Biodegradable scaffold with magnesium and glutamine accelerates bone regrowth

For most broken bones, bone cells regrow on their own while patients wear a cast or brace to keep the injury steady.

9 Sep 2025

Cancer cells found to use ketones as alternate fuel for growth

When it comes to their survival, cancer cells have a host of backup plans.

8 Sep 2025

Scientists identify key protein driving severe flu in older people

Scientists have discovered why older people are more likely to suffer severely from the flu, and can now use their findings to address this risk.

8 Sep 2025

Folic acid fortification linked to tripled gestational diabetes rates in Australian study

Researchers in Australia found that after mandatory folic acid fortification, gestational diabetes rates tripled, maternal folate levels rose sharply, and placental hormone profiles shifted. The study links folate excess to increased GDM risk, highlighting the need to re-evaluate supplementation policies.

8 Sep 2025

Mushrooms deliver nutrition medicine and sustainability solutions in one package

This Food Science & Nutrition review highlights mushrooms as nutrient-rich functional foods packed with bioactive compounds that support human health. It explores their therapeutic, industrial, and environmental applications, from disease prevention and drug discovery to bioremediation and bioenergy.

8 Sep 2025

Tarlatamab and anti-PD-L1 therapy combination demonstrates manageable safety profile in first-line ES-SCLC

Clinical data presented today demonstrates the combination of tarlatamab with anti-PD-L1 therapy as first-line maintenance has an acceptable safety profile and resulted in unprecedented overall survival in patients with extensive-stage small cell lung cancer (ES-SCLC).

8 Sep 2025

HypoRT with concurrent chemotherapy reduces treatment time and toxicity for patients with LS-SCLC

A multi-center, randomized phase III trial has found that a three-week hypofractionated radiotherapy (HypoRT) schedule with concurrent chemotherapy provides similar survival outcomes and reduced toxicity compared to the standard six-week conventional fractionated radiotherapy (ConvRT) schedule for patients with limited-stage small cell lung cancer (LS-SCLC).

8 Sep 2025

Study could pave the way for simple blood test to diagnose Alzheimer's disease

In a landmark study of Hispanic and Latino adults, researchers at University of California San Diego School of Medicine have identified a link between self-reported cognitive decline and blood-based biomarkers, which could pave the way for a simple blood test to help diagnose Alzheimer's disease and related dementias.

8 Sep 2025

Adjuvant chemo-immunotherapy may benefit patients with resected stage IB–IIIA NSCLC, trial suggests

Interim results from the NADIM ADJUVANT Phase III trial, led by the Spanish Lung Cancer Group (GECP), suggest that adjuvant chemo-immunotherapy may reduce the risk of recurrence in patients with completely resected stage IB–IIIA non-small cell lung cancer (NSCLC) while maintaining an acceptable safety profile.

8 Sep 2025

Ifinatamab deruxtecan may benefit patients with recurrent or progressive ES-SCLC

Patients diagnosed with recurrent or progressive extensive-stage small cell lung cancer (ES-SCLC) may benefit from treatment with ifinatamab deruxtecan (I-DXd), a B7-H3–directed antibody–drug conjugate, according to data presented today at the International Association for the Study of Lung Cancer (IASLC) 2025 World Conference on Lung Cancer (WCLC) in Barcelona, Spain.

8 Sep 2025

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B Cell News and Research

Special MRI technique predicts onset of mild cognitive impairment and cognitive decline

Study maps gene activity across pregnancy breastfeeding and post-weaning stages

Researchers reveal why no level of air pollution is safe for respiratory health

IFITM3 found to be critical regulator of immunotherapy sensitivity in small cell lung cancer

Amino acid homocysteine plays a key role in aortic stiffening

Researchers uncover a previously unknown mechanism behind chromosome end protection

New tool can predict where deadly brain cancer might reappear

Monitoring ctDNA can personalize the use of consolidation immunotherapy in patients with LS-SCLC

New feedback mechanism in the brain could open avenues for treating people with sleep disorders

'Resistin like molecule gamma' punches holes into heart cells after myocardial infarction

Biodegradable scaffold with magnesium and glutamine accelerates bone regrowth

Cancer cells found to use ketones as alternate fuel for growth

Scientists identify key protein driving severe flu in older people

Folic acid fortification linked to tripled gestational diabetes rates in Australian study

Mushrooms deliver nutrition medicine and sustainability solutions in one package

Tarlatamab and anti-PD-L1 therapy combination demonstrates manageable safety profile in first-line ES-SCLC

HypoRT with concurrent chemotherapy reduces treatment time and toxicity for patients with LS-SCLC

Study could pave the way for simple blood test to diagnose Alzheimer's disease

Adjuvant chemo-immunotherapy may benefit patients with resected stage IB–IIIA NSCLC, trial suggests

Ifinatamab deruxtecan may benefit patients with recurrent or progressive ES-SCLC

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