Biopsy News and Research

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Biopsy is the removal of cells or tissues for examination by a pathologist. The pathologist may study the tissue under a microscope or perform other tests on the cells or tissue. There are many different types of biopsy procedures. The most common types include: (1) incisional biopsy, in which only a sample of tissue is removed; (2) excisional biopsy, in which an entire lump or suspicious area is removed; and (3) needle biopsy, in which a sample of tissue or fluid is removed with a needle. When a wide needle is used, the procedure is called a core biopsy. When a thin needle is used, the procedure is called a fine-needle aspiration biopsy.

Blood test may predict a patient’s response to prostate cancer treatment

A team of researchers at The Institute of Cancer Research (ICR) in London found that the test can detect traces of cancer DNA in the bloodstream. The liquid biopsy could also identify the patients who are more likely to relapse.

1 Jun 2020

Genetic screening could be effective at detecting undiagnosed cases of prostate cancer

Genetic screening for prostate cancer in GP surgeries could be effective at picking up otherwise undiagnosed cases of the disease, a new pilot study shows.

31 May 2020

Targeted therapy tepotinib shows durable response in NSCLC patients with METex14 skipping mutation

Patients with advanced non-small cell lung cancer (NSCLC) and the MET exon 14 (METex14) skipping mutation had a 46.5% objective response rate to the targeted therapy drug tepotinib, as shown in a study published today in the New England Journal of Medicine and presented at the 2020 American Society of Clinical Oncology Annual Meeting ASCO20 Virtual Meeting (Abstract 9556 - Poster 322) by researchers from The University of Texas MD Anderson Cancer Center.

29 May 2020

New tool may predict best treatment for multiple myeloma

In 1844, multiple myeloma was first treated with a rhubarb pill and an infusion of orange peel. Since then, more than 15 drugs have earned FDA approval to treat multiple myeloma and with so many options, a major question has become what cocktail and sequence is best?

29 May 2020

Study: New biopsy methods can help improve benefit-harm ratio of PSA screening

The benefit of population-based PSA screening for men with an average risk of prostate cancer does not outweigh the harm caused.

29 May 2020

New device allows rapid disease analysis in kidneys affected by diabetes

The amount of scarring in damaged kidneys as a result of diabetes or acute injury, is a key factor in determining treatment. But it has not been possible, using traditional techniques, to quickly and accurately assess how widespread this kind of wounding extends within the organ.

28 May 2020

Study shows children and adults have a comparable expression of SARS-CoV-2 entry-related genes

A recent paper by researchers from China demonstrated comparable expression levels of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cell entry mediators in adults and children, suggesting that previously implied difference in viral-entry associated genes is likely not responsible for milder symptoms in children. The study is currently available on the medRxiv preprint server.

27 May 2020

New technique offers high-resolution 3D view inside tumors

Malignant tumors consume nutrients and oxygen faster than healthy cells. To do so, they recruit blood vessels in their environment. Depending on tumor type and genetic profile, there are differences on how tumors look internally.

26 May 2020

ACE2 receptors for SARS-CoV-2 in human eye

Since its emergence in Wuhan, China, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread rapidly over most of the world’s inhabited regions, causing millions of cases and hundreds of thousands of deaths. The primary symptoms of COVID-19, the disease caused by SARS-CoV-2, are fever, dry cough, and tiredness.

25 May 2020

New technique reveals potentially treatable mutations in subset of prostate cancer patients

Prostate cancer patients who do not respond well to PSMA-targeted therapy often have potentially treatable mutations in their DNA damage-repair genes, according to research published in the May issue of The Journal of Nuclear Medicine.

20 May 2020

Doctoral candidate receives NIH fellowship to study how adenovirus affects heart function

A dose of adenovirus hits most people like a common cold - a cough, a fever, maybe a sore throat. But for an unfortunate few, the usually benign bug hacks the heart's cellular electrical communication system and sometimes proves fatal.

20 May 2020

Multi-institutional clinical trial sheds new light on non-responsive tumors

Over the last decade, enzalutamide and similar drugs have led to significant tumor control and increased survival time for men who have metastatic prostate cancer that continues to grow despite treatments to reduce male hormone levels.

19 May 2020

Novel microRNA biomarker could help detect lymph node metastases in pancreatic cancer patients

For years, surgeons have operated on pancreatic cancer patients to remove what they thought was a localized tumor only to discover that the disease had spread to other, inoperable parts of the body. Now, a City of Hope molecular scientist thinks he may have found a way to prevent ineffective surgeries and prolong the lives of these patients.

18 May 2020

Fibroblasts of different pancreatic diseases exhibit distinct properties, study reveals

Fibroblasts present in different pancreatic diseases are genetically distinct and their functions are 'programmed' by the unique environment of each disease, according to new research from the University of Liverpool (UK).

18 May 2020

New noninvasive ultrasound neuromodulation technique for epilepsy treatment

Epilepsy is a central nervous system disorder characterized by recurrent seizures resulting from excessive excitation or inadequate inhibition of neurons.

15 May 2020

UOC develops new method to improve quality of CT scan imagery

Computerized tomography (CT) is one of the most effective medical tests for analyzing the effects of many illnesses, including COVID-19, on the lungs.

9 May 2020

Using photoacoustic imaging to visualize scarring in donor kidneys before transplant

When kidney transplants first came into practice in the 1950s, patients with chronic kidney disease could finally picture freedom from the unrelenting routine of blood-cleansing dialysis treatments. Just over a half-century later, demand has completely outstripped supply.

2 May 2020

Biopsy News and Research

Further Reading

Blood test may predict a patient’s response to prostate cancer treatment

Genetic screening could be effective at detecting undiagnosed cases of prostate cancer

Targeted therapy tepotinib shows durable response in NSCLC patients with METex14 skipping mutation

New tool may predict best treatment for multiple myeloma

Study: New biopsy methods can help improve benefit-harm ratio of PSA screening

New device allows rapid disease analysis in kidneys affected by diabetes

Study shows children and adults have a comparable expression of SARS-CoV-2 entry-related genes

New technique offers high-resolution 3D view inside tumors

ACE2 receptors for SARS-CoV-2 in human eye

New technique reveals potentially treatable mutations in subset of prostate cancer patients

Doctoral candidate receives NIH fellowship to study how adenovirus affects heart function

Multi-institutional clinical trial sheds new light on non-responsive tumors

Novel microRNA biomarker could help detect lymph node metastases in pancreatic cancer patients

Fibroblasts of different pancreatic diseases exhibit distinct properties, study reveals

New noninvasive ultrasound neuromodulation technique for epilepsy treatment

UOC develops new method to improve quality of CT scan imagery

Using photoacoustic imaging to visualize scarring in donor kidneys before transplant

Innovative approach offers kidney-sparing treatment option for upper tract urothelial cancer

Breakthrough study shows liquid biopsy test can safely detect 26 undiagnosed cancers

Horizon Discovery extends coverage of OncoSpan reference standards to FFPE and Liquid Biopsy

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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