High Throughput News and Research

RSS

Rigaku Analytical Devices to present during Thai Industrial Pharmacist Association (TIPA) webinar

Rigaku Analytical Devices, the market leader in handheld 1064nm Raman technology, will present its solution for raw material identification during a webinar hosted by the Thai Industrial Pharmacist Association on July 16, 2020 at 9:30 am ICT / 8:30 pm EDT.

From Rigaku Analytical Devices 6 Jul 2020

Cell 'membrane on a chip' could help test potential drug candidates for COVID-19

Researchers have developed a human cell 'membrane on a chip' that allows continuous monitoring of how drugs and infectious agents interact with our cells, and may soon be used to test potential drug candidates for COVID-19.

6 Jul 2020

Diagnosis of COVID-19 by RT-LAMP assay in 25 minutes

Even as COVID-19 continues its inexorable march, taking hundreds of thousands of lives and causing nearly 11 million cases, the diagnosis of the infection is still not sensitive or specific enough. Now, a new study by scientists at the Francis Crick Institute and published on the preprint server medRxiv...

3 Jul 2020

Common asthma drug may offer potential as treatment for Alzheimer's disease

A new study reveals that the common asthma drug salbutamol may offer potential as a treatment for Alzheimer's disease.

1 Jul 2020

Irresistin: a ‘poison arrow’ to defeat antibiotic resistance

News-Medical speaks to Dr. James Martin and Dr. Zemer Gitai from Princeton University about their research which led to the discovery of a new antibiotic.

1 Jul 2020

New approach holds incredible potential for developing new therapeutics

Nearly every drug that is, or has ever been, used was derived from nature -- harnessing compounds created by organisms over eons to fight diseases. But decades ago, biochemists postulated that it might be possible to design a new drug from scratch by linking up amino acids in precise ways.

30 Jun 2020

Study identifies small molecule inhibitors of SARS-CoV-2 which block key cellular kinases

Antiviral drug screen of kinase inhibitors, which was done by researchers from the University of California and Cedars-Sinai Medical Center, identified cellular signaling pathways critical for SARS-CoV-2 replication and revealed an important mechanism of host-pathogen interaction vital for further drug research. Their results are available on the bioRxiv* preprint server.

28 Jun 2020

Genes associated with SARS-CoV-2 human lung cell infection

Now, a new study published on the preprint server bioRxiv in June 2020 attempts to make sense of this data to identify viral genes that are explicitly expressed in the cells infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This could help reveal new therapeutic targets.

26 Jun 2020

New assay rapidly tests SARS-CoV-2 neutralization and screens antivirals

Researchers at the University of Texas Medical Branch, Galveston, have developed a new platform that can rapidly test neutralizing antibody activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and perform high-throughput screening of potential antiviral agents.

24 Jun 2020

GlobalData: NGS technology most likely to provide relief for global backlog of COVID-19 testing

Illumina receiving emergency use authorization from the Food and Drug Administration for diagnosing COVID-19 using its next generation sequencing technology could not have come at a more critical period during this pandemic.

23 Jun 2020

Highly reproducible solid phase extraction

Porvair Sciences announce Microlute CP - a new generation of Solid Phase Extraction (SPE) 96-well microplates and cartridges that take SPE to a new level of performance by enhancing the reproducibility of analyte extraction and recovery from biological, environmental and chemical samples.

From Porvair Sciences Limited 22 Jun 2020

SARS-CoV-2 saliva testing that omits the RNA extraction step

Even as the COVID-19 pandemic progresses throughout the world, the lack of consistent diagnostic testing has been a bugbear, preventing public health control of the spread of infection. A new study by researchers at the University of Illinois Urbana-Champaign and published on the preprint server bioRxiv in June 2020 reports a new testing method that uses saliva, does not require RNA extraction, and can be scaled up quickly and inexpensively.

21 Jun 2020

Characterizing "re-positives" in recovered COVID-19 patients

The novel coronavirus pandemic has been spreading silently or explosively in almost every country of the world, causing almost half a million deaths and nearly 8.5 million reported cases in just six months. While much is known about the virus and the illness by now, far more remains unclear. One such is the prevalence and persistence of antiviral immunity following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

19 Jun 2020

Novel SARS-CoV-2 antibody cocktail impeccably mimics human antibody response

By using both humanized mice and convalescent patients, the researchers from the US and Singapore successfully generated non-competing and highly potent monoclonal antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein that could potentially be combined to form antibody cocktails. Their groundbreaking paper is published in the leading research journal Science.

18 Jun 2020

Coastal Genomics automates DNA purification process using 3D printing – accelerating cancer research, prenatal screening and numerous other fields by partnering with Sculpteo

Coastal Genomics, experts in life sciences automation, selected Sculpteo, a leader in online 3D printing and digital manufacturing, to develop unique components for an automated DNA purification process.

18 Jun 2020

Scientists isolate powerful SARS-CoV-2 -neutralizing antibodies from COVID-19 patients

A new study has shown that potent antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) could help protect against COVID-19 infection. Preliminary results in animal studies have so far proven successful. The study titled, "Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model," was published in the latest issue of the journal Science.

17 Jun 2020

Accelerating the Diagnosis and Treatment of Cancer with Mass-Spectrometry Based Techniques

An interview with Livia Eberlin, Assistant Professor at the University of Texas at Austin, discussing the development of mass-spectrometry based techniques for cancer diagnosis and improved clinical outcomes.

From Pittcon 16 Jun 2020

Trio of studies identifies new human antibodies that target SARS-CoV-2 virus

A trio of papers describes several newly discovered human antibodies that target the SARS-CoV-2 virus, isolated from survivors of SARS-CoV-2 and SARS-CoV infection.

15 Jun 2020

Dante Labs, Cambridge Cancer Genomics and Nonacus collaborate to provide precision oncology at scale

Dante Labs, Cambridge Cancer Genomics, and Nonacus, today announced that they have signed a collaboration agreement.