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The intranasal route of immunization may offer effective protection against SARS-CoV-2

Researchers at the School of Medicine, Washington University in Saint Louis, USA, showed that the intranasal route of immunization could provide a more efficient protection against SARS-CoV-2 compared to the intramuscular route (i.e. through ‘jabs’).

7 Dec 2020

Potential SARS-CoV-2 Mpro inhibitors identified by in silico screening

The search for effective inhibitors of SARS-CoV-2 is assuming new urgency as the fall/winter resurgence of the infection appears.

7 Dec 2020

Targeting senescent 'zombie' cells may improve survival in women with cervical cancer

How well women with cervical cancer respond to treatment and survive correlates with the level of 10 proteins in their blood that also are associated with a "zombie" cell state called senescence, Medical College of Georgia scientists report.

7 Dec 2020

Study reveals genetic abnormalities that cause brain aneurysms

Nearly three percent of the world's population is at risk of developing an intracranial aneurysm, a localized dilation of a blood vessel forming a fragile pocket. Rupture of this aneurysm results in extremely severe, and, in one-third of cases, fatal hemorrhage.

7 Dec 2020

Molecular simulations reveal that remdesivir targets two SARS-CoV-2 enzymes

Remdesivir has been shown to target both RNA-dependent RNA polymerase and main protease of SARS-CoV-2 – resulting in a ‘double whammy’ effect.

7 Dec 2020

Topoisomerase 1 inhibition prevents SARS-CoV-2-induced inflammation and death in animal models

A new study indicates that the topoisomerase 1 (Top1) is intimately related to the lethal inflammation associated with SARS-CoV-2 infection in a large proportion of cases.

7 Dec 2020

FDA authorizes first COVID-19 test to detect COVID-19, influenza A and B

Today, the U.S. Food and Drug Administration authorized the first diagnostic test for at home collection of patient samples to detect both COVID-19 and influenza A and B (flu).

7 Dec 2020

Clinical investigators present abstracts on hematological malignancies at ASH Annual Meeting and Exposition

Clinical investigators from Hackensack Meridian Health John Theurer Cancer Center (JTCC), a member of the Georgetown Lombardi Comprehensive Cancer Center consortium, are to present updates on treatment advances in multiple myeloma (MM), mantle cell lymphoma (MCL), and other types of B-cell lymphoma (BCL) as well as leukemia at the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition, to be held virtually from December 5-8, 2020.

7 Dec 2020

Combination of venetoclax and standard therapies shows promise in high-risk myeloid blood cancers

The novel oral drug venetoclax can be safely added to standard therapies for some high-risk myeloid blood cancers and in early studies the combination shows promise of improved outcomes, say scientists from Dana-Farber Cancer Institute.

7 Dec 2020

Researchers identify potential drug combination to treat uveal melanoma

Researchers at Huntsman Cancer Institute (HCI) at the University of Utah (U of U) have identified a potential drug combination to treat uveal melanoma, a type of eye cancer.

7 Dec 2020

Study: CAR T-cell therapy reduced cancer cells in patients with advanced non-Hodgkin lymphoma

A CAR T-cell therapy known as axicabtagene ciloleucel (axi-cel) drove cancer cells to undetectable levels in nearly 80% of patients with advanced non-Hodgkin lymphoma (NHL) in a phase 2 clinical trial.

6 Dec 2020

Study proposes new plan to help reduce financial hardships for cancer patients

Until you or a loved one are facing treatment for a cancer diagnosis, you may not realize the cost associated with treatment and doctor visits.

6 Dec 2020

Lung tissue analysis reveals promising molecular target to ameliorate pulmonary fibrosis

An analysis of lung tissues from patients with different types of pulmonary fibrosis - including cases triggered by COVID-19 - has revealed a promising molecular target to ameliorate the chronic and irreversible disease.

5 Dec 2020

Researchers develop wound-healing gel based on a substance produced by Trichoderma fungi

Researchers from the Department of Biochemistry of RUDN University developed a wound-healing gel based on a substance that is produced by Trichoderma fungi.

5 Dec 2020

Missing link between stress and infertility found

Otago researchers have found the "missing link between stress and infertility".

5 Dec 2020

Biochemical cascade in the brain leads to the destruction of synapses in Alzheimer's

A new study on Alzheimer's disease by Scripps Research scientists has revealed a previously unknown biochemical cascade in the brain that leads to the destruction of synapses, the connections between nerve cells that are responsible for memory and cognition.

5 Dec 2020

Drugs News and Research

The intranasal route of immunization may offer effective protection against SARS-CoV-2

Potential SARS-CoV-2 Mpro inhibitors identified by in silico screening

Targeting senescent 'zombie' cells may improve survival in women with cervical cancer

Study reveals genetic abnormalities that cause brain aneurysms

Molecular simulations reveal that remdesivir targets two SARS-CoV-2 enzymes

Topoisomerase 1 inhibition prevents SARS-CoV-2-induced inflammation and death in animal models

FDA authorizes first COVID-19 test to detect COVID-19, influenza A and B

Clinical investigators present abstracts on hematological malignancies at ASH Annual Meeting and Exposition

Combination of venetoclax and standard therapies shows promise in high-risk myeloid blood cancers

Researchers identify potential drug combination to treat uveal melanoma

Study: CAR T-cell therapy reduced cancer cells in patients with advanced non-Hodgkin lymphoma

Study proposes new plan to help reduce financial hardships for cancer patients

Lung tissue analysis reveals promising molecular target to ameliorate pulmonary fibrosis

Researchers develop wound-healing gel based on a substance produced by Trichoderma fungi

Missing link between stress and infertility found

Biochemical cascade in the brain leads to the destruction of synapses in Alzheimer's

Is mask-wearing effective in preventing SARS-CoV-2 transmission?

TSK Laboratory’s Low Dead Space needles can help vaccinate millions more against COVID-19

FUJIFILM Irvine Scientific launches Sterile Express Media Service

Study shows how minerals come together at molecular level to form bones, hard tissues

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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