Receptor News and Research

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Researchers take major step forward in developing real ALS treatments

A series of studies begun by Harvard Stem Cell Institute scientists eight years ago has lead to a report published today that may be a major step forward in the quest to develop real treatments for amyotrophic lateral sclerosis, ALS, or Lou Gehrig's disease.

7 Aug 2014

New approach for understanding auditory localization in patients with hearing aids under background noise

Patients with implanted artificial cochlea often complain that they cannot recognize speech well in natural environments, especially if background of noise is present.

6 Aug 2014

Researchers receive $435K to study how environmental factors affect genes that cause autism

Over the last decade, autism research has been primarily focused on finding genes that may "cause" autism. However, little information exists on gene-environment interactions that may increase risk for autism.

5 Aug 2014

Researchers at NIH-FEI Living Lab for Structural Biology achieve breakthrough biological results

FEI is pleased to announce that researchers at the NIH-FEI Living Lab for Structural Biology have achieved breakthrough biological results, using FEI’s Titan Krios™ transmission electron microscope (TEM), to elucidate the structural mechanism by which glutamate receptors participate in the transmission of signals between neurons in the brain. Their work is described in Nature, “Structural Mechanism of Glutamate Receptor Activation and Desensitization,” by Meyerson, et al., (DOI: 10.1038/nature13603), http://www.nature.com/nature/journal/vaop/ncurrent/full/nature13603.html .

From Thermo Fisher Scientific – Electron Microscopy Solutions 4 Aug 2014

Bacteria that aid in digestion help keep intestinal lining intact

Scientists at Albert Einstein College of Medicine of Yeshiva University have found that bacteria that aid in digestion help keep the intestinal lining intact.

4 Aug 2014

Researchers uncover 3D structure of neuroreceptor

Neurons are the cells of our brain, spinal cord, and overall nervous system. They form complex networks to communicate with each other through electrical signals that are carried by chemicals.

4 Aug 2014

Study: Spicy capsaicin can reduce risk of colorectal tumors

Researchers at the University of California, San Diego School of Medicine report that dietary capsaicin - the active ingredient in chili peppers - produces chronic activation of a receptor on cells lining the intestines of mice, triggering a reaction that ultimately reduces the risk of colorectal tumors.

3 Aug 2014

Biologists identify signaling pathway that switches on calorie-burning process in brown fat cells

Biologists at The Scripps Research Institute (TSRI) have identified a signaling pathway that switches on a powerful calorie-burning process in brown fat cells.

1 Aug 2014

Researchers identify possible new drug target for treating childhood blood cancer

In what is believed to be the largest genetic analysis of what triggers and propels progression of tumor growth in a common childhood blood cancer, researchers at NYU Langone Medical Center report that they have identified a possible new drug target for treating the disease.

1 Aug 2014

Study provides platform for detailed study of nerve injury and repair during Wallerian degeneration

Wallerian degeneration is a subject of major interest in neuroscience. A large number of genes are differentially regulated during the distinct stages of Wallerian degeneration: transcription factor activation, immune response, myelin cell differentiation and dedifferentiation.

31 Jul 2014

No two single tumor cells in breast cancer patients have same genome

Just as no two people possess the same genetic makeup, a recent study has shown that no two single tumor cells in breast cancer patients have an identical genome.

31 Jul 2014

Acupuncture helps cut fatigue, anxiety and depression in breast cancer patients using aromatase inhibitors

Use of electroacupuncture (EA) - a form of acupuncture where a small electric current is passed between pairs of acupuncture needles - produces significant improvements in fatigue, anxiety and depression in as little as eight weeks for early stage breast cancer patients experiencing joint pain related to the use of aromatase inhibitors (AIs) to treat breast cancer.

31 Jul 2014

Obesity mutation MC4R can significantly contribute to weight gain at early age

People who have the most common genetic mutation linked to obesity respond differently to pictures of appetizing foods than overweight or obese people who do not have the genetic mutation, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

31 Jul 2014

Alterations to single gene could predict risk of suicide attempt

Johns Hopkins researchers say they have discovered a chemical alteration in a single human gene linked to stress reactions that, if confirmed in larger studies, could give doctors a simple blood test to reliably predict a person's risk of attempting suicide.

30 Jul 2014

EMD Serono begins MSB0010718C Phase II study in mMCC patients

EMD Serono, Inc., a subsidiary of Merck KGaA, Darmstadt, Germany, today announced the initiation of an international Phase II study designed to assess the efficacy and safety of MSB0010718C, an investigational fully human IgG1 monoclonal antibody that binds to programmed death-ligand 1 (PD-L1).

29 Jul 2014

GSK announces availability of once-weekly Tanzeum in pharmacies throughout the U.S.

GSK today announced that once-weekly Tanzeum (albiglutide), a prescription injectable treatment for type 2 diabetes in adults, as an adjunct to diet and exercise, is now available in pharmacies throughout the U.S.

29 Jul 2014

Neuroscientists shed new light on how the brain works

Neuroscientists in Bonn and Heidelberg have succeeded in providing new insights into how the brain works. Researchers at the DZNE and the German Cancer Research Center analyzed tissue samples from mice to identify how two specific proteins, ‘CKAMP44’ and ‘TARP Gamma-8’, act upon the brain’s memory center.

26 Jul 2014

UTHealth scientists identify inhibitory switch to prevent peripheral vascular disease

Millions of people in the United States have a circulatory problem of the legs called peripheral vascular disease. It can be painful and may even require surgery in serious cases. This disease can lead to severe skeletal muscle wasting and, in turn, limb amputation.

25 Jul 2014

Children who experience stress early in life have emotional, physical health problems

Children who have been abused or neglected early in life are at risk for developing both emotional and physical health problems.

25 Jul 2014

Research suggests effective role for natural steroid hormones in treating breast cancer

A new study supports a growing body of research suggesting a safe and effective role for natural steroid hormones in treating postmenopausal breast cancer, with fewer detrimental side effects and improved health profile than with standard anti-hormone therapies.

24 Jul 2014

Receptor News and Research

Researchers take major step forward in developing real ALS treatments

New approach for understanding auditory localization in patients with hearing aids under background noise

Researchers receive $435K to study how environmental factors affect genes that cause autism

Researchers at NIH-FEI Living Lab for Structural Biology achieve breakthrough biological results

Bacteria that aid in digestion help keep intestinal lining intact

Researchers uncover 3D structure of neuroreceptor

Study: Spicy capsaicin can reduce risk of colorectal tumors

Biologists identify signaling pathway that switches on calorie-burning process in brown fat cells

Researchers identify possible new drug target for treating childhood blood cancer

Study provides platform for detailed study of nerve injury and repair during Wallerian degeneration

No two single tumor cells in breast cancer patients have same genome

Acupuncture helps cut fatigue, anxiety and depression in breast cancer patients using aromatase inhibitors

Obesity mutation MC4R can significantly contribute to weight gain at early age

Alterations to single gene could predict risk of suicide attempt

EMD Serono begins MSB0010718C Phase II study in mMCC patients

GSK announces availability of once-weekly Tanzeum in pharmacies throughout the U.S.

Neuroscientists shed new light on how the brain works

UTHealth scientists identify inhibitory switch to prevent peripheral vascular disease

Children who experience stress early in life have emotional, physical health problems

Research suggests effective role for natural steroid hormones in treating breast cancer

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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