Antidepressant News and Research

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Antidepressants are medicines that treat depression. Your doctor can prescribe them for you. They can improve your mood, sleep, appetite and concentration. It may take several weeks for them to help. There are several types of antidepressants. You and your doctor may have to try several before finding what works best for you.

New study shows antidepressant use increases among people with no psychiatric diagnosis

Americans are no strangers to antidepressants. During the last 20 years the use of antidepressants has grown significantly making them one of the most costly and the third most commonly prescribed class of medications in the U. S.

6 Aug 2011

Risperidone does not appear to reduce military-related PTSD symptoms

Patients with military-related, chronic posttraumatic stress disorder (PTSD) and symptoms that were not improved with use of an antidepressant medication did not experience a reduction in PTSD symptoms with use of the antipsychotic medication risperidone, according to a study in the August 3 issue of JAMA, a theme issue on violence and human rights.

3 Aug 2011

New generation antidepressants may increase risk of adverse outcomes in elderly

Older people taking new generation antidepressants are at more risk of dying or suffering from a range of serious health conditions including stroke, falls, fractures and epilepsy, a study involving researchers at The University of Nottingham has found.

3 Aug 2011

Post-traumatic stress disorder drug risperidone not working: Study

According to a new study a medication commonly used to treat post-traumatic stress disorder in combat veterans may not be effective in reducing overall PTSD severity.

3 Aug 2011

Antidepressants ineffective in Alzheimer’s: Study

According to a new study published in the medical journal The Lancet on Tuesday, two antidepressants that are commonly given to Alzheimer's disease patients appear not only to be ineffective but may give side effects such as nausea and drowsiness. Researchers urged doctors to think twice before prescribing these drugs to Alzheimer's patients with depression.

20 Jul 2011

Patients who use anti-depressants more likely to suffer relapses

Patients who use anti-depressants are much more likely to suffer relapses of major depression than those who use no medication at all, concludes a McMaster researcher.

20 Jul 2011

Positive results from levomilnacipran Phase III study for major depressive disorder

Forest Laboratories, Inc. and Pierre Fabre Medicament today announced preliminary top-line results from a Phase III study of levomilnacipran for the treatment of adults with major depressive disorder (MDD).

18 Jul 2011

New antidepressant prescription linked to increased risk of falls in nursing home residents

Nursing home residents taking certain antidepressant medications are at an increased risk of falling in the days following the start of a new prescription or a dose increase of their current drug, according to a new study by the Institute for Aging Research of Hebrew SeniorLife, an affiliate of Harvard Medical School.

16 Jul 2011

Regular exercise may help prevent panic and related disorders

Regular exercise may be a useful strategy for helping prevent the development of panic and related disorders, a new study suggests.

13 Jul 2011

Research roundup: Rural hospitals have poorer quality; Cost-effective migraine relief; Doctors still take Medicare

Quality Of Care And Patient Outcomes In Critical Access Rural Hospitals -- This study looks at the quality of care provided by patterns of care at "critical access hospitals," a federal designation for hospitals that serve rural populations and thus have been granted special incentives under Medicare.

8 Jul 2011

Antidepressants during first trimester linked to increased risk of autism

Prenatal exposure to selective serotonin reuptake inhibitors, especially during the first trimester, is associated with a modest increase the risk of developing an autism spectrum disorder, according to a report published Online First in the Archives of General Psychiatry, one of the JAMA/Archives journals.

5 Jul 2011

Some drug mixtures may be fatal for elderly: study

British scientists warn that well known brands of hay fever tablets, painkillers and sleeping pills pose a previously unknown threat to elderly people’s health when taken together. Many are available over the counter at pharmacies as well as being prescribed by GPs, nurses and chemists they said.

23 Jun 2011

Enrollment complete in Rexahn's Serdaxin Phase IIb clinical trial for major depressive disorder

Rexahn Pharmaceuticals, Inc., a clinical stage pharmaceutical company developing and commercializing potential best in class oncology and CNS therapeutics, today announced that it has completed enrollment in its Phase IIb clinical trial of Serdaxin to treat major depressive disorder (MDD).

22 Jun 2011

Naurex commences GLYX-13 Phase II trial in treatment-resistant depression

Naurex Inc., a clinical-stage company developing innovative treatments to address unmet needs in psychiatry and neurology, today announced that it has initiated a Phase II clinical trial of its lead compound GLYX-13.

22 Jun 2011

One in ten Europe's middle-aged citizens took antidepressants during 2010

New research from the University of Warwick and the IZA Institute in Bonn shows that 10% of middle-aged Europeans took antidepressants in 2010. The researchers looked in detail at the lives of a randomly selected sample of nearly 30,000 Europeans. The study covered 27 countries.

20 Jun 2011

Fast-acting antidepressant effect of ketamine

UT Southwestern Medical Center scientists are shedding new light on why the anesthetic drug ketamine produces a fast-acting antidepressant response in patients with treatment-resistant depression.

17 Jun 2011

Study finds no link between anxiety, depression and weight loss after bariatric surgery

Depression and anxiety do not seem to interfere with the amount of weight loss or the improvement of obesity-related conditions after bariatric surgery, according to a new study of more than 25,000 patients presented here at the 28th Annual Meeting of the American Society for Metabolic & Bariatric Surgery.

16 Jun 2011

Brain research funds crisis: Report

According to the European College of Neuropsychopharmacology there is a dramatic drop in private and public funding for research in brain diseases that has led to a “withdrawal of hope” for millions of sufferers and could delay the search for treatments and cures by 30 years.

16 Jun 2011

Alkermes commences ALKS 5461 phase 1/2 study for treatment-resistant depression

Alkermes, Inc. today announced the initiation of a phase 1/2 study of ALKS 5461 for treatment-resistant depression (TRD). ALKS 5461 is the combination of ALKS 33, a proprietary opioid modulator, and buprenorphine. TRD, which is also known as refractory depression, refers to depressive episodes that are not adequately controlled by standard antidepressant therapy.

15 Jun 2011

New findings from Deplin clinical trial on major depressive disorder presented at NCDEU

New findings from a multi-center, randomized, placebo-controlled clinical study of Deplin 15mg added to commonly prescribed antidepressants known as selective serotonin reuptake inhibitors showed that all patients who achieved remission at 30 days using Deplin 15mg adjuvant therapy, and who chose to enter a 12 month maintenance phase, maintained their remission after a year of treatment.

14 Jun 2011

Antidepressant News and Research

Further Reading

New study shows antidepressant use increases among people with no psychiatric diagnosis

Risperidone does not appear to reduce military-related PTSD symptoms

New generation antidepressants may increase risk of adverse outcomes in elderly

Post-traumatic stress disorder drug risperidone not working: Study

Antidepressants ineffective in Alzheimer’s: Study

Patients who use anti-depressants more likely to suffer relapses

Positive results from levomilnacipran Phase III study for major depressive disorder

New antidepressant prescription linked to increased risk of falls in nursing home residents

Regular exercise may help prevent panic and related disorders

Research roundup: Rural hospitals have poorer quality; Cost-effective migraine relief; Doctors still take Medicare

Antidepressants during first trimester linked to increased risk of autism

Some drug mixtures may be fatal for elderly: study

Enrollment complete in Rexahn's Serdaxin Phase IIb clinical trial for major depressive disorder

Naurex commences GLYX-13 Phase II trial in treatment-resistant depression

One in ten Europe's middle-aged citizens took antidepressants during 2010

Fast-acting antidepressant effect of ketamine

Study finds no link between anxiety, depression and weight loss after bariatric surgery

Brain research funds crisis: Report

Alkermes commences ALKS 5461 phase 1/2 study for treatment-resistant depression

New findings from Deplin clinical trial on major depressive disorder presented at NCDEU

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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