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Study sheds new light on how diabetes contributes to the development of Alzheimer’s disease

New research from the University of Eastern Finland explores the role of diabetes in the cellular and molecular changes underlying Alzheimer's disease.

18 Nov 2020

Certain regions in the retina are more affected by Alzheimer's disease, shows study

A study led by the Cedars-Sinai Department of Neurosurgery has identified certain regions in the retina - the lining found in the back of the eye - that are more affected by Alzheimer's disease than other areas.

18 Nov 2020

Affinity-Bead Assisted Mass Spectrometry for Proteomics

In this interview, Ghaith Hamza from AstraZeneca talks to News-Medical Life Sciences about the basic principles of Affinity-Bead Assisted Mass Spectrometry (Affi-BAMS) and how Affi-BAMS can help target specific proteins for proteomic applications.

From Bruker Daltonics 16 Nov 2020

Research provides insight into how Alzheimer’s plaques form

We are beginning to better understand how 'amyloid-β' protein plaques form, which are implicated in degenerative brain diseases including Alzheimer's and Parkinson's diseases.

16 Nov 2020

Study could pave the way for potential urine test to diagnose liver fibrosis

Fifty fragments of proteins, termed peptides, have been identified in the urine of liver fibrosis patients in a new study that could pave the way for a potential diagnostic urine test for the condition if further validated.

16 Nov 2020

Consumption of teff grain boosts the composition, function of stomach microbiome

The seeds of a teff plant - which look similar to wheat - are tiny in stature, but they pack a nutritional wallop.

16 Nov 2020

Drugs targeting neutrophils could reduce ARDS in severe COVID-19

Scientists in Taiwan recently published a report on their use of anti-neutrophil strategies to treat acute respiratory distress syndrome (ARDS) – a life-threatening condition that can arise in critical COVID-19 cases – in the journal Frontiers in Pediatrics.

15 Nov 2020

Harnessing proteomics could improve therapeutic approaches to COVID-19

A research group in India has recently described how the field of proteomics could be pivotal in helping to tackle the current coronavirus disease 2019 (COVID-19) pandemic.

15 Nov 2020

Promising SARS-CoV-2 N epitope for more accurate diagnostic and surveillance antibody testing

A new study published on the preprint server bioRxiv in November 2020 describes the virus's N protein as a promising epitope for serology.

12 Nov 2020

New process helps preserve viral vaccines without refrigeration

Ever receive a vaccination that seemed to burn a lot while it was injected? The vaccine solution likely contained a lot of salt or sugar - natural preservatives that help keep it stable, in addition to the cold temperature at which it was kept.

12 Nov 2020

PhoreMost and Oxford Biomedica collaborate to develop next-generation CAR-T cell therapies

PhoreMost Limited, the UK-based biopharmaceutical company dedicated to developing drugs against intractable disease targets, and Oxford Biomedica plc, a leading gene and cell therapy group, today announced that they have entered into a discovery collaboration to develop next-generation CAR-T cell therapies.

From PhoreMost 10 Nov 2020

Lateral flow test enables faster, accurate diagnosis of periprosthetic joint infection

The recently FDA-authorized alpha-defensin lateral flow test is a highly accurate, ten-minute test for diagnosis of periprosthetic joint infection (PJI) - a serious and costly complication of total joint replacement, reports a study in The Journal of Bone & Joint Surgery.

9 Nov 2020

Majority of population likely has pre-existing immunity to SARS-CoV-2, claim researchers

A team of researchers has conducted a study suggesting that the majority of the global population is likely to have pre-existing T-cell immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent responsible for the coronavirus disease 2019 (COVID-19) pandemic.

9 Nov 2020

Study describes the effects of a DPP3-knockout on the renin-angiotensin system

The role of the enzyme dipeptidyl peptidase 3 in the blood pressure-regulating renin-angiotensin system was investigated in the inter-university cooperation project BioTechMed-Graz. The results could pave the way for new therapies for cardio-renal diseases.

5 Nov 2020

Study shows brilacidin strongly inhibits SARS-CoV-2 in laboratory cell lines

A recent study by US researchers reveals that brilacidin, a small synthetic molecule with peptide-like properties, exerts potent in vitro antiviral activity against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – both as a standalone treatment and in combination with FDA-approved remdesivir. The study is currently available on the bioRxiv preprint server.

4 Nov 2020

Researchers use new approach to study the mechanisms of cellular uptake of amyloid beta

One of the hallmarks of Alzheimer's disease is the formation of amyloid plaques--sticky clumps of a protein called amyloid beta--that collect between neurons in the brain.

3 Nov 2020

Beetroot peptide may be a good candidate for development of a drug to treat inflammatory diseases

In a recent study, a research group led by Christian Gruber at MedUni Vienna's Institute of Pharmacology isolated a peptide (small protein molecule) from beetroot.

30 Oct 2020

Lung biomarkers may predict severe COVID-19

Two University of New Mexico researchers postulate certain specific biomarkers' relevance in predicting the potential for progression to severe COVID-19 in a paper published on the preprint server bioRxiv*

27 Oct 2020

New peptide derivatives that target the SARS-CoV-2 spike protein

In a new study published in the journal Cellular and Molecular Bioengineering, researchers report peptide derivatives, or peptidomimetics, based on the circle residues involved in the interaction of the spike protein and ACE2.

26 Oct 2020

NRP-1 receptor potentiates SARS-CoV-2 infectivity

The COVID-19 pandemic is still actively spreading in many parts of the world, causing redoubled efforts to develop antivirals and vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A recent study explores the role of a second type of cell surface receptor, called neuropilin, in the virus's entry into the host cell and its subsequent replication.

26 Oct 2020

Peptides News and Research

Study sheds new light on how diabetes contributes to the development of Alzheimer’s disease

Certain regions in the retina are more affected by Alzheimer's disease, shows study

Affinity-Bead Assisted Mass Spectrometry for Proteomics

Research provides insight into how Alzheimer’s plaques form

Study could pave the way for potential urine test to diagnose liver fibrosis

Consumption of teff grain boosts the composition, function of stomach microbiome

Drugs targeting neutrophils could reduce ARDS in severe COVID-19

Harnessing proteomics could improve therapeutic approaches to COVID-19

Promising SARS-CoV-2 N epitope for more accurate diagnostic and surveillance antibody testing

New process helps preserve viral vaccines without refrigeration

PhoreMost and Oxford Biomedica collaborate to develop next-generation CAR-T cell therapies

Lateral flow test enables faster, accurate diagnosis of periprosthetic joint infection

Majority of population likely has pre-existing immunity to SARS-CoV-2, claim researchers

Study describes the effects of a DPP3-knockout on the renin-angiotensin system

Study shows brilacidin strongly inhibits SARS-CoV-2 in laboratory cell lines

Researchers use new approach to study the mechanisms of cellular uptake of amyloid beta

Beetroot peptide may be a good candidate for development of a drug to treat inflammatory diseases

Lung biomarkers may predict severe COVID-19

New peptide derivatives that target the SARS-CoV-2 spike protein

NRP-1 receptor potentiates SARS-CoV-2 infectivity

Editorial Focus eBook - Peptides and Oligonucleotides (2nd edition) eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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