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Understanding biomolecular frustration could help design better drugs

Knowing precisely where proteins are frustrated could go a long way toward making better drugs.

23 Nov 2020

FDA expands approved indication for influenza treatment to include post-exposure prevention

Today, the U.S. Food and Drug Administration expanded the approved indication for Xofluza (baloxavir marboxil) to include post-exposure prevention of influenza (flu) for patients 12 years of age and older after contact with an individual who has the flu.

23 Nov 2020

Reprogramming T cells into highly active 'super immune cells' can improve immunotherapy benefits

Immune-system T cells have been reprogrammed into regenerative stem cell-like memory (TSCM) cells that are long-lived, highly active "super immune cells" with strong antitumor activity, according to new research from Georgetown Lombardi Comprehensive Cancer Center.

23 Nov 2020

UNC scientists find brain cells that help drive arousal responses to strong emotions

Strong emotions such as fear and anxiety tend to be accompanied and reinforced by measurable bodily changes including increased blood pressure, heart rate and respiration, and dilation of the eyes' pupils. These so-called "physiological arousal responses" are often abnormally high or low in psychiatric illnesses such as anxiety disorders and depression.

23 Nov 2020

Targeting excessive calcium may provide a new way to improve outcomes in stroke patients

Excessive calcium contributes to harmful inflammation in ischemic stroke, and targeting it may provide doctors with a new way to improve patient outcomes, new research from the University of Virginia School of Medicine suggests.

23 Nov 2020

Scientists make breakthrough in studying the enzyme involved in fish odor syndrome

Fish odor syndrome (trimethylaminuria) is a debilitating disease, in which the liver cannot break down the smelly chemical trimethylamine which is produced by enzymes from bacteria residing in the gut leaving people with a fish like odor.

23 Nov 2020

Researchers develop recombinant SARS-CoV-2 model to aid vaccine and antiviral research

Researchers have developed a fluorescent reporter gene-bearing recombinant form of SARS-CoV-2, which is capable of replication.

23 Nov 2020

FDA schedules meeting to discuss emergency use authorization of COVID-19 vaccine from Pfizer

Today, the U.S. Food and Drug Administration issued an emergency use authorization (EUA) for casirivimab and imdevimab to be administered together for the treatment of mild to moderate COVID-19 in adults and pediatric patients (12 years of age or older weighing at least 40 kilograms [about 88 pounds]) with positive results of direct SARS-CoV-2 viral testing and who are at high risk for progressing to severe COVID-19.

23 Nov 2020

Signaling pathway promotes cancer growth by blocking pro-growth signals from second major cancer pathway

Sometimes, too much of a good thing can turn out to be bad. This is certainly the case for the excessive cell growth found in cancer. But when cancers try to grow too fast, this excessive speed can cause a type of cellular ageing that actually results in arrested growth.

23 Nov 2020

Researchers discover mechanism by which abnormal proteins unleash toxicity in neurodegenerative diseases

Thanks to modern medicine, humans tend to live much longer than before. Unfortunately, this also opens a wider window to develop chronic diseases with late onset, such as neurodegenerative diseases.

23 Nov 2020

FDA schedules meeting to discuss emergency use authorization of COVID-19 vaccine from Pfizer

The U.S. Food and Drug Administration has scheduled a meeting of its Vaccines and Related Biological Products Advisory Committee (VRBPAC) on Dec. 10 to discuss the request for emergency use authorization (EUA) of a COVID-19 vaccine from Pfizer, Inc. in partnership with BioNTech Manufacturing GmbH.

23 Nov 2020

Sage and perilla herbal teas could help to prevent or treat COVID-19

Researchers in Germany have conducted a study demonstrating the potential antiviral effects of commonly consumed herbal teas on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the pathogen that causes coronavirus disease 2019 (COVID-19).

22 Nov 2020

Sexual minorities who misuse alcohol or tobacco also have a co-occurring psychiatric disorder

More than half of lesbian, gay and bisexual individuals who misuse alcohol or tobacco also have a co-occurring psychiatric disorder, compared to one-third of heterosexuals, a new University of Michigan study finds.

20 Nov 2020

State-of-the-art technology provides high levels of accuracy in breast cancer diagnosis

State-of-the-art technology which helps doctors more accurately diagnose breast cancer has been hailed as a breakthrough by the US Food & Drugs Administration (FDA) for its exceptional potential clinical value in improving patient care.

20 Nov 2020

Research reveals T-cell abnormalities in severe COVID-19 cases

There is an idea within the coronavirus research field that there is some kind of T cell abnormality in critically ill COVID-19 patients, but specific details have not yet been clarified.

20 Nov 2020

UVA researchers discover gene responsible for the metastasis of triple-negative breast cancer

University of Virginia Cancer Center researchers have identified a gene responsible for the spread of triple-negative breast cancer to other parts of the body - a process called metastasis - and developed a potential way to stop it.

20 Nov 2020

KHN’s ‘What the Health?’: Transition troubles mount as COVID spreads

President-elect Joe Biden is still being blocked from launching his official transition while President Donald Trump contests the outcome of the election. That could be particularly dangerous for public health as COVID-19 spreads around the country at an alarming rate.

20 Nov 2020

Drugs News and Research

Understanding biomolecular frustration could help design better drugs

FDA expands approved indication for influenza treatment to include post-exposure prevention

Reprogramming T cells into highly active 'super immune cells' can improve immunotherapy benefits

UNC scientists find brain cells that help drive arousal responses to strong emotions

Targeting excessive calcium may provide a new way to improve outcomes in stroke patients

Scientists make breakthrough in studying the enzyme involved in fish odor syndrome

Researchers develop recombinant SARS-CoV-2 model to aid vaccine and antiviral research

FDA schedules meeting to discuss emergency use authorization of COVID-19 vaccine from Pfizer

Signaling pathway promotes cancer growth by blocking pro-growth signals from second major cancer pathway

Researchers discover mechanism by which abnormal proteins unleash toxicity in neurodegenerative diseases

FDA schedules meeting to discuss emergency use authorization of COVID-19 vaccine from Pfizer

Sage and perilla herbal teas could help to prevent or treat COVID-19

Sexual minorities who misuse alcohol or tobacco also have a co-occurring psychiatric disorder

State-of-the-art technology provides high levels of accuracy in breast cancer diagnosis

Research reveals T-cell abnormalities in severe COVID-19 cases

UVA researchers discover gene responsible for the metastasis of triple-negative breast cancer

KHN’s ‘What the Health?’: Transition troubles mount as COVID spreads

The Prospects of Semaglutide for Treatment of Type 2 Diabetes Patients

Scientists exploit 'trojan horse' feature in SARS-CoV-2 virus to create antivirals against COVID-19

Study addresses gap in the discovery of new antibiotics

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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